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HEAL - Cardiomyocyte transplantation to induce myocardial regeneration

HEAL - Cardiomyocyte transplantation to induce myocardial regeneration

HEAL will focus on development of a potential new therapeutic treatment option for heart failure by using induced pluripotent stem cell-derived cardiomyocytes for cardiac repair. HLA-homozygous cell line derived cardiomyocyte aggregates offer the prospect of a restorative heart therapy applicable to large patient populations and to overcome economic barriers associated with autologous approaches. Within the consortium tools and knowledge to accelerate the development of advanced iPSC-based therapies will be developed, ultimately towards optimization of cell-product administration in terms of retention and engraftment in the UMCU.

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