Epigenomics Facility

Epigenomics Facility

People involved uitklapper, klik om te openen

Michal Mokry

Noortje van den Dungen

Gerard Pasterkamp

Key Publications uitklapper, klik om te openen

1. Haitjema S, Meddens CA, Van Der Laan SW, Kofink D, Harakalova M, Tragante V, Foroughi Asl H, Van Setten J, Brandt MM, Bis JC, O'Donnell C, Cheng C, Hoefer IE, Waltenberger J, Biessen E, Jukema JW, Doevendans PAFM, Nieuwenhuis EES, Erdmann J, Björkegren JLM, Pasterkamp G, *Asselbergs FW, Den *Ruijter HM, *Mokry M. Additional Candidate Genes for Human Atherosclerotic Disease Identified Through Annotation Based on Chromatin Organization. Circulation: Cardiovascular Genetics 2017;10. *equal contribution

2. Petrelli A, Mijnheer G, Hoytema Van Konijnenburg DP, Van Der Wal MM, Giovannone B, Mocholi E, Vazirpanah N, Broen JC, Hijnen D, Oldenburg B, Coffer PJ, Vastert SJ, Prakken BJ, Spierings E, Pandit A, Mokry M, Van Wijk F. PD-1+CD8+ T cells are clonally expanding effectors in human chronic inflammation. Journal of Clinical Investigation 2018;128:4669-4681.

3. Pei J, Harakalova M, Treibel TA, Lumbers RT, Boukens BJ, Efimov IR, van Dinter JT, González A, López B, El Azzouzi H, van den Dungen N, van Dijk CGM, Krebber MM, den Ruijter HM, Pasterkamp G, Duncker DJ, Nieuwenhuis EES, de Weger R, Huibers MM, Vink A, Moore JH, Moon JC, Verhaar MC, Kararigas G, Mokry M*, Asselbergs FW*, Cheng C*. H3K27ac acetylome signatures reveal the epigenomic reorganization in remodeled non-failing human hearts. Clin Epigenetics. 2020 Jul 14;12(1):106. doi: 10.1186/s13148-020-00895-5. 

4. Meddens CA, Harakalova M, van den Dungen NA, Foroughi Asl H, Hijma HJ, Cuppen EP, Björkegren JL, Asselbergs FW, Nieuwenhuis EES, Mokry M. (2016) Systematic analysis of chromatin interactions at disease associated loci links novel candidate genes to inflammatory bowel disease. Genome Biology 2016 Nov 30;17(1):247.

Contact uitklapper, klik om te openen

Dr. Michal Mokry, m.mokry@umcutrecht.nl