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Group Stokroos
Group Stokroos

Tinnitus is a complex and heterogenous condition. The tinnitus research group focusses at the prevalence and characterization of tinnitus in adults and children.

About

Creating subtypes is one of the main goals to improve outcome of treatment by improving patient selection for specific treatments. Different experimental treatments are investigated in randomized controlled study designs to explore the effect of cochlear implants, psychological therapy and neurostimulation on tinnitus outcome. Thereby, studying and improving quality of research is of upmost importance to open up research outcomes for the patient and the physician and improve clinical care for these patients.   

Research topics

Tinnitus cochlear implants, subtyping, deep brain stimulation, vagus nerve stimulation, TMS, CBT, mindfulness, quality of reporting, publication bias, childhood tinnitus

Group members

  • Prof. dr. R.J. Stokroos, otologist, department of Otorhinolaryngology, Head and Neck Surgery, UMC Utrecht
  • Dr. A.L. Smit, otologist, department of Otorhinolaryngology, Head and Neck Surgery, UMC Utrecht
  • Dr. I. Stegeman, epidemiologist, department of Otorhinolaryngology, Head and Neck Surgery, UMC Utrecht
  • Drs. A.F. Lieftink, psychologist, department of Otorhinolaryngology, Head and Neck Surgery, UMC Utrecht
  • Drs. M. Rademaker, PhD-candidate, department of Otorhinolaryngology, Head and Neck Surgery, UMC Utrecht
  • Drs. K. Assouly, PhD-candidate, department of Otorhinolaryngology, Head and Neck Surgery, UMC Utrecht
  • Drs. J.P.M Peters, PhD-candidate, department of Otorhinolaryngology, Head and Neck Surgery, UMC Utrecht
  • Drs. A.W. Wendrich, PhD-candidate, department of Otorhinolaryngology, Head and Neck Surgery, UMC Utrecht
  • Drs. J. van Heteren, PhD-candidate, department of Otorhinolaryngology, Head and Neck Surgery, UMC Utrecht

Alumni / PhD theses

Key publications

Development and internal validation of a multivariable prediction model for tinnitus recovery following unilateral cochlear implantation: a cross-sectional retrospective study. Ramakers GGJ, van Zanten GA, Thomeer HGXM, Stokroos RJ, Heymans MW, Stegeman I. BMJ Open. 2018 Jun 11;8(6):e021068. doi: 10.1136/bmjopen-2017-021068.

Effect of unilateral and simultaneous bilateral cochlear implantation on tinnitus: A Prospective Study. van Zon A, Smulders YE, Ramakers GG, Stegeman I, Smit AL, Van Zanten GA, Stokroos RJ, Hendrice N, Free RH, Maat B, Frijns JH, Mylanus EA, Huinck WJ, Topsakal V, Tange RA, Grolman W. Laryngoscope. 2016 Apr;126(4):956-61. doi: 10.1002/lary.25493. Epub 2015 Aug 8. PMID: 26255618

Socio-demographic, health, and tinnitus related variables affecting tinnitus severity. Hoekstra CE, Wesdorp FM, van Zanten GA. Ear Hear. 2014 Sep-Oct;35(5):544-54. doi: 10.1097/AUD.0000000000000045. PMID: 25003528

Bilateral low-frequency repetitive transcranial magnetic stimulation of the auditory cortex in tinnitus patients is not effective: a randomised controlled trial. Hoekstra CE, Versnel H, Neggers SF, Niesten ME, van Zanten GA. Audiol Neurootol. 2013;18(6):362-73. doi: 10.1159/000354977. Epub 2013 Oct 19. PMID: 24157459

Measuring disease-specific health-related quality of life to evaluate treatment outcomes in tinnitus patients: a systematic review. Kamalski DM, Hoekstra CE, van Zanten BG, Grolman W, Rovers MM. Otolaryngol Head Neck Surg. 2010 Aug;143(2):181-5. doi: 10.1016/j.otohns.2010.03.026. Review. PMID: 20647116

The risk of bias in randomized controlled trials in otorhinolaryngology: hardly any improvement since 1950. Peters JPM, Stegeman I, Grolman W, Hooft L. BMC Ear Nose Throat Disord. 2017 Apr 18;17:3. doi: 10.1186/s12901-017-0036-x. eCollection 2017.

Related websites

Funding and grants

- 2018 Grant Revalidatiefonds Effectiveness Mindfulness Therapy for tinnitus

 - 2019 Cochlear Ltd Effectiveness of Tinnitus implant and subtyping of tinnitus patients

Collaborations

  • TIN-ACT partner
  • Stichting Hoormij
  • KNO vereniging