Jeroen Pasterkamp Group

Our research focuses on understanding 1) the molecular mechanisms involved in the development of neuronal connections, and 2) the disease mechanisms responsible for changes in or loss of neuronal connectivity during epilepsy and motor neuron disorders (ALS, SMA). RNA biology (RNA binding proteins, non-coding RNAs) and axon guidance proteins play a central role in many of our projects, as do mouse genetics, humanized cell models (iPSC, organoids), molecular cell biology, and (light sheet) microscopy.

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