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Microbiome Center Utrecht
Microbiome Center Utrecht

About us

We are all continuously exposed to a vast number of bacteria that colonize many body sites including our intestinal tract, skin and upper respiratory tract. The Microbiome Center Utrecht studies how the interactions between the microbiota and the human host affect health and disease. By using state of the art technology, including 16S rRNA profiling, metagenomic and meta-transcriptomic sequencing, anaerobic microbiota culturomics, in vitro and in vivo models of disease, tissue culture, organoids and, we aim to understand the mechanisms behind the complex relationships between the microbiota and the host. Our main mission is to use this knowledge to predict and prevent the development of disease, and pave the road for novel therapeutics approaches.
Our Microbiome Facility, which is an integral part of the Utrecht Exposome Hub, provides support for various types of microbiome profiling and analysis to various (clinical) research groups within and outside the UMC Utrecht.

Team

Prof. Rob Willems


Population Genetics of Antibiotic Resistance

Dr. Fernanda Paganelli



Microbiomics, intestinal organoid-bacterial interactions

Dr. Marcel de Zoete



Molecular and cellular host-microbiota interactions, culturomics, pathobionts

Dr. Anita Schürch



Pathogen genomics, microbiome

Dr. Helen Leavis



Clinical Immunology, primary immunodeficiency, autoinflammatory diseases

Prof. Janneke van de Wijgert



Public health epidemiology, vaginal microbiome

Expertise, Equipment & Facilities

16s rRNA
Metagenomic
Whole Genome Sequencing 
Analysis
Culturomics
Anaerobic culturing
Organoids bacteria interactions