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Infection and Immunity nieuws

May 29: Dutch hospitals start trial to improve care for people with systemic sclerosis

A new way of working, based on eHealth, should improve the care for people with systemic sclerosis. With an app, patients with systemic sclerosis and their practitioner can exchange data with national experts. University Medical Center (UMC) Utrecht is working together with other hospitals through this app, which helps to generate the best treatment plan.

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May 24: Micro-RNAs disrupt the immune system in both systemic sclerosis and Sjögren's syndrome

MicroRNAs disrupt the functioning of plasmacytoid dendritic cells and thereby play a role in the development of systemic autoimmune diseases such as systemic sclerosis and Sjögren's syndrome. This is the conclusion of Eleni Chouri in her dissertation, on which she was awarded a PhD in Utrecht on May 23.

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May 23: Infectious disease control research projects receive ZonMw grant

In a supplemental round of the Infectious Disease Control program of ZonMw (subsidy provider in the field of health research and care innovation), 12 projects with a duration of up to 18 months were approved. Three of these projects went to researchers who are connected to the strategic theme Infection & Immunity at UMC Utrecht.

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May 21: Research UMC Utrecht provides new insights into the in vivo dynamics of lymphocytes

PhD student Mariona Baliu-Piqué investigated the lifespan, the loss and the production rates as well as the circulation through the body of different types of lymphocytes.

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May 13: Tailor-made chemo reduces mortality risk from stem cell transplantation

More accurate dosing of fludarabine chemotherapy may lead to a better chance of survival after donor stem cell transplantation. This was concluded from the doctoral research at University Medical Center (UMC) Utrecht by Jurgen Langenhorst into mathematical models that can improve the results of stem cell transplantation.

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Apr 26: Immune cells behave differently in a joint than in the blood

Certain immune cells (the so-called T-cells) that inhibit harmful autoimmune reactions in the joints in healthy people appear to not work well in people with juvenile idiopathic arthritis (JIA), causing joint damage. This is one of the conclusions of the research by Gerdien Mijnheer who obtained her PhD on 18 April in Utrecht.

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Apr 17: Childhood infections and long-term health consequences

Adolescents who have had many infections as a child may have a greater risk of atherosclerosis. A possible causal relationship should be further investigated, according to Annemarijn Prins-van Ginkel who obtained her PhD on 16 April in Utrecht.

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Apr 13: Organizations Join Forces to Create Global Alliance Against Antibiotic Resistance

The U.S.-based Antibacterial Resistance Leadership Group (ARLG), part of the Duke Clinical Research Institute (DCRI) and the University Medical Center (UMC) Utrecht, the managing entity of the COMBACTE (Combatting Bacterial Resistance in Europe) consortium, will work together to solidify a comprehensive global community to combat the threat of antibiotic resistance around the world.

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Apr 5: Potential target for streptococcal vaccine identified

Researchers have identified a new modification - glycerol phosphate - on the surface of the Group A Streptococcus bacterium. This opens up possibilities for developing a vaccine against this pathogen.

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Apr 2: T-cell recovery is essential for survival after stem cell transplantation in children

The better and faster the population of certain immune cells (so-called T cells) recovers after a donor stem cell transplant in children, the lowe the risk of serious complications and the higher the chance of survival. These are the striking conclusions of Coco de Koning's research for which she was awarded a PhD in Utrecht last thursday.

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