Department of Genetics - Research
The research section of the Department of Genetics uses genomics and bioinformatics approaches to understand the genetic basis of disease. Expertise and state-of-the-art infrastructure is available for next-generation DNA sequencing, single molecule sequencing, genotyping, metabolomics, bioinformatics and a broad range of model systems, including patient-derived primary cultures, iPS cells, zebrafish and organoid culturing.
Researchers in the section aim to identify and molecularly characterise novel disease-driving mechanisms and focus on orphan diseases, cardiogenetics, neurogenetics, nephrogenetics, congenital disease, metabolic disease, complex syndromal disorders, and cancer. Our research section consists of six pre-clinical and clinical research groups, which are strongly embedded within the UMC Utrecht strategic teams: Child Health, Brain Center, Circulatory Health, and Cancer.