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prof. dr. K.P.J. (Kees) Braun

prof. dr. K.P.J. (Kees) Braun

Full Professor
prof. dr. K.P.J. (Kees) Braun
  • Neurologen

Research Programs

Brain

Biography

Biography

Kees Braun obtained his Medical Degree at Utrecht University in January 1992. He specialized in Neurology (registered in 2000) and Paediatric Neurology (registered in 2002) in the UMC Utrecht. In 2000 he obtained his PhD degree on a thesis entitled “Magnetic Resonance Spectroscopy in Hydrocephalus. He was appointed as staff neurologist in 2000 and paediatric neurologist in 2002. Since 2011 he is head of Paediatric Neurology/Neurosurgery.  In May 2012 he was appointed as a full professor of Paediatric Neurology.

His clinical and scientific areas of expertise are: refractory paediatric epilepsy, epilepsy surgery,  imaging in epilepsy, and childhood arteriopathic stroke, in particular moyamoya treatment.

He coordinates epilepsy research in the  UMCU Brain center. The epilepsy research projects he is personally involved in  focus on the effects of focal epilepsy on the brain in animal models and patients (structural and functional integrity and network analysis); seizure- and cognitive outcome after paediatric epilepsy surgery; postoperative antiepileptic drug withdrawal; ESES treatment; stress and epilepsy; and epileptic focus detection in surgical candidates.

Kees Braun currently is president of the Dutch Society of Paediatric Neurology and of the organizing committee of the 2016 world congress of child neurology (ICNC) in Amsterdam. He is member of the European Task Force for Epilepsy Surgery in Children (U-Task), the European Network for Epilepsy Research (ENER), and work-package leader of the EU-funded E-PILEPSY project.

Research line

Refractory epilepsy

Most recent key publications

1: Boshuisen K, Arzimanoglou A, Cross JH, Uiterwaal CS, Polster T, van Nieuwenhuizen O, Braun KP; for the TimeToStop study Group. Timing of antiepileptic drug withdrawal and long-term seizure outcome after paediatric epilepsy surgery (TimeToStop): a retrospective observational study. Lancet Neurol 2012:11:784-791
2: Van Campen JS, Jansen FE, Pet MA, Otte WM, Hillegers MH, Joels M, Braun KP. Relation between stress-precipitated seizures and the stress response in childhood epilepsy. Brain 2015;138:2234-2248
3: Lamberink HJ, Boshuisen K, van Rijen PC, Gosselaar PH, Braun KP. Changing profiles of pediatric epilepsy surgery candidates over time: a nationwide single-center experience from 1990 to 2011. Epilepsia 215;56:717-725
4: Boshuisen K, van Schooneveld MM, Uiterwaal CS, Cross JH, Harrison S, Polster T, Daehn M, Djimjadi S, Yalnizoglu D, Turanli G, Sassen R, Hoppe C, Kuczaty S, Barba C, Kahane P, Schubert-Bast S, Reuner G, Bast T, Strobl K, Mayer H, de Saint-Martin A, Seegmuller C, Laurent A, Arzimanoglou A, Braun KP, for the TimeToStop cognitive outcome study group. Intelligence quotient improves after antiepileptic drug withdrawal following pediatric epilepsy surgery. Ann Neurol 2015;78:104-114
5: Braun KPJ, Bulder MMM, Chabrier S, Kirkham FJ, Uiterwaal CSP, Tardieu M, Sebire G. Longitudinal vascular imaging in 79 children with ischemic stroke and unilateral intracranial arteriopathy. Brain 2009;132:544-557

Side Activities

As mentioned in the Biography.

Fellowship and Awards

1: Recipient of the first “Patrick Hanlo Award”, March 17 2009
2: Personal investment grant for epilepsy research by the Dutch National Epilepsy Fund
3: Recipient of the “Gerlach Cerfontaine Fellowship” of the Catharijne Foundation, UMCU, 1998-2000, for the PhD project “Magnetic Resonance Spectroscopy in Hydrocephalus”
4: Recipient of several research grants from e.g. the Dutch Epilepsy Fund, Johanna Children’s Fund, and Wilhelmina Research Fund.

Research Output (279)

Personality traits of children before and after epilepsy surgery

Braams Olga B., Schappin Renske, Meekes Joost, van Rijen Peter C, van Nieuwenhuizen Onno, Braun Kees P, Jennekens-Schinkel Aag Jul 2017, In: Epilepsy Research. 133 , p. 10-12 3 p.

Individualised prediction model of seizure recurrence and long-term outcomes after withdrawal of antiepileptic drugs in seizure-free patients:a systematic review and individual participant data meta-analysis

Lamberink Herm J, Otte Willem M, Geerts Ada T, Pavlovic Milen, Ramos-Lizana Julio, Marson Anthony G, Overweg Jan, Sauma Letícia, Specchio Luigi M, Tennison Michael, Cardoso Tania M O, Shinnar Shlomo, Schmidt Dieter, Geleijns Karin, Braun Kees P J Jul 2017, In: Lancet Neurology. 16 , p. 523-531 9 p.

Seven tesla MRI improves detection of focal cortical dysplasia in patients with refractory focal epilepsy

Veersema Tim J, Ferrier Cyrille H, van Eijsden Pieter, Gosselaar Peter H, Aronica Eleonora, Visser Fredy, Zwanenburg Jaco M, de Kort Gerard A P, Hendrikse Jeroen, Luijten Peter R, Braun Kees P J Jun 2017, In: Epilepsia Open. 2 , p. 162-171 10 p.

Genetic and phenotypic heterogeneity suggest therapeutic implications in SCN2A-related disorders

Wolff Markus et al. 1 May 2017, In: Brain. 140 , p. 1316-1336 21 p.

Cognitive and behavioral outcome after epilepsy surgery in children, part of Cognition and Behaviour in Childhood Epilepsy edited by Lieven Lagae

van Schooneveld MMJ, Braun KPJ, Cross J.H. May 2017, p. 172-186 15 p.

Current standards of neuropsychological assessment in epilepsy surgery centers across Europe

Vogt Viola Lara, Äikiä Marja, Del Barrio Antonio, Boon Paul, Borbély Csaba, Bran Ema, Braun Kees, Carette Evelien, Clark Maria, Cross Judith Helen, Dimova Petia, Fabo Daniel, Foroglou Nikolaos, Francione Stefano, Gersamia Anna, Gil-Nagel Antonio, Guekht Alla, Harrison Sue, Hecimovic Hrvoje, Heminghyt Einar, Hirsch Edouard, Javurkova Alena, Kälviäinen Reetta, Kavan Nicole, Kelemen Anna, Kimiskidis Vasilios K, Kirschner Margarita, Kleitz Catherine, Kobulashvili Teia, Kosmidis Mary H, Kurtish Selin Yagci, Lesourd Mathieu, Ljunggren Sofia, Lossius Morten Ingvar, Malmgren Kristina, Mameniskiené Ruta, Martin-Sanfilippo Patricia, Marusic Petr, Miatton Marijke, Özkara Çiğdem, Pelle Federica, Rubboli Guido, Rudebeck Sarah, Ryvlin Philippe, van Schooneveld Monique, Schmid Elisabeth, Schmidt Pia-Magdalena, Seeck Margitta, Steinhoff Bernhard J, Shavel-Jessop Sara, Mar 2017, In: Epilepsia. 58 , p. 343–355 13 p.

Punctate white matter lesions in full-term infants with neonatal seizures associated with SLC13A5 mutations

Weeke Lauren C, Brilstra Eva, Braun Kees P, Zonneveld-Huijssoon Evelien, Salomons Gajja S, Koeleman BPC, van Gassen Koen L, van Straaten Henrica L, Craiu Dana, de Vries Linda S Mar 2017, In: European Journal of Paediatric Neurology. 21 , p. 396-403 8 p.

Preventing cognitive impairment in children with epilepsy

Braun Kees P J 30 Jan 2017, In: Current Opinion in Neurology. 30 , p. 140-147 8 p.

Association of motor milestones, SMN2 copy and outcome in spinal muscular atrophy types 0-4

Wadman Renske I, Stam Marloes, Gijzen Marleen, Lemmink Henny H, Snoeck Irina N, Wijngaarde Camiel A, Braun Kees P J, Schoenmakers Marja A G C, van den Berg Leonard H, Dooijes Dennis, van der Pol W-Ludo 20 Jan 2017, In: Journal of Neurology, Neurosurgery and Psychiatry. 88 , p. 364-367 4 p.

Risks and Benefits of Rituximab in the Treatment of Hashimoto Encephalopathy in Children:Two Case Reports and a Mini Review

Maas Annemieke, Braun Kees P J, Geleijns Karin, Jansen Floor E., van Royen-Kerkhof Annet Jan 2017, In: Pediatric Neurology. 66 , p. 28-31 4 p.

All research output

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