prof. dr. A.C.G. (Toine) Egberts

Full Professor

  • Clinical Pharmacy

prof. dr. A.C.G. (Toine) Egberts


Toine Egberts (1965) obtained his PharmD in 1990 at the University of Groningen, the Netherlands. Thereafter he was trained as a clinical pharmacist during four years in the hospitals of Tilburg and Delft. In 1994, he started his PhD project at the department of Pharmacoepidemiology & Clinical Pharmacology of Utrecht University in collaboration with the Netherlands Pharmacovigilance Foundation 'Lareb'. This resulted in 1997 in a thesis entitled 'Pharmacoepidemiologic approaches to the evaluation of antidepressant drugs'. During his PhD-project he obtained the Master of Science degree in clinical epidemiology at the Netherlands Institute of Health Sciences.

He was appointed in 2001 as professor of clinical pharmacoepidemiology at the department of Pharmacoepidemiology & Clinical Pharmacology. Since 2006 he is also a professor of clinical pharmacy at the medical faculty of Utrecht University. In these positions he tries to bridge the drug environment and the patient environment.

From 2006 - 2017 he was the chief pharmacist of the department of clinical pharmacy of the University Medical Center Utrecht.

Since november 2018 he is director of doctor education of the Graduate School of Life Sciences of the Utrecht University. The coaching of PhD students gives him energy as it nicely balances performing research into medical/pharmaceutical puzzles with the personal development of young academic professionals. He had the opportunity to guide over 60 PhD students towards the 'hora est'. He has always been deeply involved in education, especially the training of hospital pharmacists, for which he received in 2016 the 'Senior Jan Glerum Award'.

He is (co)author of over 450 international peer reviewed scientific publications and a reviewer for several scientific journals and international research funding organisations.

He is a member of the editorial board of the journal Drug Safety. He is member of several committees such as the CCMO, the Netherlands Expertcenter for Pharmacotherapy for older people (EPHOR), the scientific advisory board of the Mental Health Center of the University of Wurzburg.

His research activities focus on a) the clinical pharmacology / clinical pharmacoepidemiology of drugs used in the treatment of psychiatric and neurologic disorders, and b) on innovations in clinical pharmacy systems.

He is married to Karin, has two daughters (Bibi and Louisa) and one son (Kilian) and in his spare time he likes to (trail)run, bootcamp, climb mountains and to play / listen to music.

Side Activities

  • All mentioned activities are current:

    • professor of clinical pharmacy, department of pharmaceutical sciences Utrecht University
    • director of doctoral education Graduate School of Life Sciences Utrecht University
    • member CCMO
    • advisor clinical pharmacology group Jeroen Bossch Ziekenhuizen
    • member of the working group for a clinical guideline on deprescribing Quality Insitute Federation Medical Specialists
    • reviewer of project proposals for funding organizsations such as ZonMw
    • member of the editorial board of the journal Drug Safety
    • reviewer for several biomedical journals
    • board member of the Netherlands Expertcenter for Pharmacotherapy for older people (EPHOR)
    • chiar of the stichting KNMP fondsen
    • member scientific advisory board Zentrum fur Psychische Gesundheit, Uniklinikum Wurzburg, Germany

Fellowship and Awards

  • Huizinga Penning (2004)

    Senior Jan Glerum prijs (2016)

Research Output (496)

Psychotropic medication use in former ICU patients with mental health problems:A prospective observational follow-up study

Janssen Debbie G A, Jonker Joep, van Dijk Diederik, Heerdink Eibert R, Egberts Toine C G, Slooter Arjen J C okt 2020, In: Journal of Critical Care. 59 , p. 112-117 6 p.

Association between serum biomarkers CEA and LDH and response in advanced non-small cell lung cancer patients treated with platinum-based chemotherapy

de Jong Corine, Deneer Vera H M, Kelder Johannes C, Ruven Henk, Egberts Toine C G, Herder Gerarda J M jul 2020, In: Thoracic cancer. 11 , p. 1790-1800 11 p.

Experiences with medical cannabis in the treatment of veterans with PTSD:Results from a focus group discussion

Krediet Erwin, Janssen Debbie Ga, Heerdink Eibert R, Egberts Toine Cg, Vermetten Eric jul 2020, In: European Neuropsychopharmacology. 36 , p. 244-254 11 p.

Adverse events related to biologicals used for patients with multiple sclerosis:a comparison between information originating from regulators and information originating from the scientific community

Minnema L. A., Giezen T. J., Egberts T. C.G., Leufkens H. G.M., Gardarsdottir H. jul 2020, In: European Journal of Neurology. 27 , p. 1250-1256 7 p.

Clinical rule-guided pharmacists' intervention in hospitalized patients with hypokalaemia:A time series analysis

Wasylewicz Arthur T.M., Korsten Erik H.M., Egberts Toine C.G., Grouls Rene J.E. jun 2020, In: Journal of Clinical Pharmacy and Therapeutics. 45 , p. 520-529 10 p.

Reporting Patterns of Sialorrhea Comparing Users of Clozapine to Users of Other Antipsychotics:A Disproportionality Analysis Using VigiBase

Man Wai Hong, Wilting Ingeborg, Souverein Patrick, Meyboom Ronald, Egberts Toine, Heerdink Eibert R. 1 mei 2020, In: Journal of clinical psychopharmacology. 40 , p. 283-286 4 p.

A semi-mechanistic model based on glutathione depletion to describe intra-individual reduction in busulfan clearance

Langenhorst J B, Boss J, van Kesteren C, Lalmohamed A, Kuball J, Egberts A C G, Boelens J J, Huitema A D R, van Maarseveen E M 18 feb 2020, In: British Journal of Clinical Pharmacology. 86 , p. 1499-1509 11 p.

The association between receptor binding affinity and metabolic side effect profile of antipsychotics and major cardio- and cerebrovascular events:A case/non-case study using VigiBase

Aguiar João Pedro, Alves da Costa Filipa, Egberts Toine, Leufkens Hubert, Souverein Patrick 1 jan 2020, In: European Neuropsychopharmacology. 35 , p. 30-38 9 p.

Discontinuation Rates of Antidepressant Use by Dutch Soldiers

Janssen Debbie G.A., Vermetten Eric, Egberts Toine C.G., Heerdink Eibert R. 1 dec 2019, In: Military Medicine. 184 , p. 868-874 7 p.

Associations between personality traits and adequate home storage of drugs in older patients

Vlieland N. D., van den Bemt B. J.F., Wouters H., Egberts A. C.G., Bouvy Marcel, Gardarsdottir H. 26 nov 2019, In: Psychology, Health and Medicine. 24 , p. 1255-1266 12 p.

All Research Output (496)