prof. dr. J.H.H.M. (Janneke) van de Wijgert

prof. dr. J.H.H.M. (Janneke) van de Wijgert

Full Professor
prof. dr. J.H.H.M. (Janneke) van de Wijgert
  • Julius Center, dept. Epidemiology & Health Economics
  • Julius Center Research Program Infectious Diseases

Research Programs

Infection & Immunity



Prof. Janneke van de Wijgert, MD PhD MPH, is a translational infectious disease researcher, educated in biomedical sciences and medicine (Utrecht University, Netherlands), and public health epidemiology (University of California at Berkeley, USA). Her work experience includes clinical epidemiological and public health research, laboratory research, and product development in various European, African, Asian, and American countries. Former employers include the University of California at San Francisco (5 years of which as Director of the UZ-UCSF Collaborative HIV Research Program in Harare, Zimbabwe), the Population Council in New York, the Amsterdam University Medical Center, and the University of Liverpool, UK. She was appointed Full Professor in the Julius Center for Health Sciences and Primary Care of the University Medical Center (UMC) Utrecht in 2017, and as Chief Science Officer at the Dutch Institute of Public Health and the Environment (RIVM) in 2022. She currently divides her time between the UMC Utrecht and the RIVM. She has supervised/is supervising multiple PhD, Master’s and Bachelor students, and has published more than 200 peer-reviewed papers. 
Janneke van de Wijgert’s main areas of research and teaching include 1) general infectious and immune-mediated disease epidemiology (including COVID-19); 2) the role of the human microbiome in health and disease; 3) the role of the cervicovaginal microbiome in reproductive and neonatal health and disease, and in prevention of HIV transmission; and 4) evaluation of diagnostics, treatments, and prevention interventions in these areas. In addition to traditional epidemiological approaches, she has specialised in incorporating ‘-omics’ and other complex biological data into epidemiological models. During the COVID-19 epidemic, she has worked with eHealth applications to control epidemic spread.

A complete list of publications can be found on ORCID:



Side Activities

Chief Science Officer, Dutch Institute of Public Health and the Environment (RIVM; as of 1 March 2022).

Member of the "Begeleidingscommissie Digitale Ondersteuning Bestrijding Covid-19" of the Dutch Ministry of Health and Sports (May 2020-Feb 2022).

Regular peer reviewer for journals and funding agencies (ongoing).

Regular invited speaker, session chair, or Scientific Advisory Committee member at scientific meetings and conferences (ongoing).

Unpaid advisor of biotech companies in infectious disease diagnostics and therapeutics (ongoing).

Research Output (98)

BCG Vaccination of Health Care Workers Does Not Reduce SARS-CoV-2 Infections nor Infection Severity or Duration:a Randomized Placebo-Controlled Trial

Claus Juana, Ten Doesschate Thijs, Gumbs Cheyenne, van Werkhoven Cornelis H, van der Vaart Thomas W, Janssen Axel B, Smits Gaby, van Binnendijk Rob, van der Klis Fiona, van Baarle Debbie, Paganelli Fernanda L, Leavis Helen, Verhagen Lilly M, Joosten Simone A, Bonten Marc J M, Netea Mihai G, van de Wijgert Janneke H H M, 28 Mar 2023, In: mBio. 14 16 p.

Vulvovaginal yeast infections during pregnancy and perinatal outcomes:systematic review and meta-analysis

Gigi Ranjana M S, Buitrago-Garcia Diana, Taghavi Katayoun, Dunaiski Cara-Mia, van de Wijgert Janneke H H M, Peters Remco P H, Low Nicola 21 Mar 2023, In: BMC Women's Health. 23

The endometrial microbiota of women with or without a live birth within 12 months after a first failed IVF/ICSI cycle

Bui Bich Ngoc, van Hoogenhuijze Nienke, Viveen Marco, Mol Femke, Teklenburg Gijs, de Bruin Jan Peter, Besselink Dagmar, Brentjens Linda Stevens, Mackens Shari, Rogers Malbert R.C., Steba Gaby S., Broekmans Frank, Paganelli Fernanda L., van de Wijgert Janneke H.H.M. 1 Mar 2023, In: Scientific Reports. 13 , p. 1-11

Effectiveness of bivalent mRNA booster vaccination against SARS-CoV-2 Omicron infection, the Netherlands, September to December 2022

Huiberts Anne J, de Gier Brechje, Hoeve Christina E, de Melker Hester E, Hahné Susan Jm, center Radboud, van de Wijgert Janneke Hhm, van den Hof Susan, Knol Mirjam J 16 Feb 2023, In: Eurosurveillance. 28

Urine and vaginal microbiota compositions of postmenopausal and premenopausal women differ regardless of recurrent urinary tract infection and renal transplant status

Hugenholtz Floor, van der Veer Charlotte, Terpstra Matty L, Borgdorff Hanneke, van Houdt Robin, Bruisten Sylvia, Geerlings Suzanne E, van de Wijgert Janneke H H M Dec 2022, In: Scientific Reports. 12

Head-to-head comparison of the accuracy of saliva and nasal rapid antigen SARS-CoV-2 self-testing:cross-sectional study

Schuit Ewoud, Venekamp Roderick P., Veldhuijzen Irene K., van den Bijllaardt Wouter, Pas Suzan D., Stohr Joep J.J.M., Lodder Esther B., Hellwich Marloes, Molenkamp Richard, Igloi Zsofia, Wijers Constantijn, Vroom Irene H., Nagel-Imming Carla R.S., Han Wanda G.H., Kluytmans Jan A.J.W., van den Hof Susan, van de Wijgert Janneke H.H.M., Moons Karel G.M. 24 Oct 2022, In: BMC Medicine. 20

Changes in concentrations of cervicovaginal immune mediators across the menstrual cycle:a systematic review and meta-analysis of individual patient data

Hughes Sean M, Levy Claire N, Katz Ronit, Lokken Erica M, Anahtar Melis N, Hall Melissa Barousse, Bradley Frideborg, Castle Philip E, Cortez Valerie, Doncel Gustavo F, Fichorova Raina, Fidel Paul L, Fowke Keith R, Francis Suzanna C, Ghosh Mimi, Hwang Loris Y, Jais Mariel, Jespers Vicky, Joag Vineet, Kaul Rupert, Kyongo Jordan, Lahey Timothy, Li Huiying, Makinde Julia, McKinnon Lyle R, Moscicki Anna-Barbara, Novak Richard M, Patel Mickey V, Sriprasert Intira, Thurman Andrea R, Yegorov Sergey, Mugo Nelly Rwamba, Roxby Alison C, Micks Elizabeth, Hladik Florian, , van de Wijgert Janneke H. 5 Oct 2022, In: BMC Medicine. 20

Diagnostic accuracy of covid-19 rapid antigen tests with unsupervised self-sampling in people with symptoms in the omicron period:cross sectional study

Schuit Ewoud, Venekamp Roderick P., Hooft Lotty, Veldhuijzen Irene K., van den Bijllaardt Wouter, Pas Suzan D., Zwart Vivian F., Lodder Esther B., Hellwich Marloes, Koppelman Marco, Molenkamp Richard, Wijers Constantijn J.H., Vroom Irene H., Smeets Leonard C., Nagel-Imming Carla R.S., Han Wanda G.H., van den Hof Susan, Kluytmans Jan A.J.W., van de Wijgert Janneke H.H.M., Moons Karel G.M. 14 Sep 2022, In: BMJ (Clinical research ed.). 378

Vaginal bacterium Prevotella timonensis turns protective Langerhans cells into HIV-1 reservoirs for virus dissemination

van Teijlingen Nienke H, Helgers Leanne C, Sarrami-Forooshani Ramin, Zijlstra-Willems Esther M, van Hamme John L, Segui-Perez Celia, van Smoorenburg Marleen Y, Borgdorff Hanneke, van de Wijgert Janneke Hhm, van Leeuwen Elisabeth, van der Post Joris Am, Strijbis Karin, Ribeiro Carla Ms, Geijtenbeek Teunis Bh 15 Aug 2022, In: EMBO Journal. 41

Thoracic imaging tests for the diagnosis of COVID-19

Ebrahimzadeh Sanam, Islam Nayaar, Dawit Haben, Salameh Jean Paul, Kazi Sakib, Fabiano Nicholas, Treanor Lee, Absi Marissa, Ahmad Faraz, Rooprai Paul, Al Khalil Ahmed, Harper Kelly, Kamra Neil, Leeflang Mariska M.G., Hooft Lotty, van der Pol Christian B., Prager Ross, Hare Samanjit S., Dennie Carole, Spijker René, Deeks Jonathan J., Dinnes Jacqueline, Jenniskens Kevin, Korevaar Daniël A., Cohen Jérémie F., Van den Bruel Ann, Takwoingi Yemisi, van de Wijgert Janneke, Wang Junfeng, Pena Elena, Sabongui Sandra, McInnes Matthew D.F., 16 May 2022, In: The Cochrane database of systematic reviews. 2022

All research output

Thank you for your review!

Has this information helped you?

Please tell us why, so that we can improve our website.

Working at UMC Utrecht





Practical maakt gebruik van cookies

Deze website maakt gebruik van cookies Deze website toont video’s van o.a. YouTube. Dergelijke partijen plaatsen cookies (third party cookies). Als u deze cookies niet wilt kunt u dat hier aangeven. Wij plaatsen zelf ook cookies om onze site te verbeteren.

Lees meer over het cookiebeleid

Akkoord Nee, liever niet