dr. M.B. (Marc) Bierings

dr. M.B. (Marc) Bierings

Associate Professor - medical
dr. M.B. (Marc) Bierings
  • SCT patient care



Marc Bierings is a pediatric hematologist. He studied medicine at the University of Utrecht. He subsequently obtained his PhD in Rotterdam on transplacental iron transport (cum laude) and then trained as a pediatrician in Utrecht.

The Dutch Cancer Society then awarded him a fellowship in pediatric hemato-oncology. He worked in the University Hospitals of Tubingen, Germany and  Amsterdam to train as a pediatric hemato-oncologist. After finishing his fellowship he became a member of staff at the Utrecht University Children’s Hospital and has been head of the department of pediatric hematology since 2005.

He spent 6 months in the department of hematology at St Louis Hospital, Paris with prof Eliane Gluckman in 2005.

He is also program director of the pediatric stem cell transplantation program, one of 2 such teams in the Netherlands. Within the Dutch Childhood Oncology Group he holds positions as chair of the Fanconi and aplastic anemia groups, the stem cell group and is member of several ALL committees of the DCOG.

His main interests are in the role of allogeneic stem cell transplantation in pediatric malignancies and marrow failure syndromes.

He represents the pediatric oncologists in the Cooperation Board of the Princess Maxima Centre, as a board member of the DCOG.

Side Activities

  • Lid Cooperatiebestuur Prinses Maxima Centrum
  • Lid Raad van Toezicht SKION
  • SKION Protocolcommissie ALL11: lid
  • SKION Fanconi anemie commissie: voorzitter
  • SKION SAA commissie: voorzitter
  • SKION Taakgroep Stamceltransplantatie: voorzitter
  • SKION dagen commissie: lid
  • Lid redactie Ned Tijdschrift Hematologie
  • Bestuurslid Ned Ver Hematologie
  • Lid Medische adviesraad Stichting Zeldzame Bloedziekten

Fellowship and Awards

  • 1995 - 1997 KWF fellowship

Research Output (263)

ESTRO ACROP and SIOPE recommendations for myeloablative total body irradiation in children

Hoeben Bianca A W, Pazos Montserrat, Seravalli Enrica, Bosman Mirjam E, Losert Christoph, Albert Michael H, Boterberg Tom, Ospovat Inna, Mico Milla Soraya, Abakay Candan Demiroz, Engellau Jacob, Johansson Vilberg, Kos Gregor, Supiot Stéphane, Llagostera Camille, Bierings Marc, Scarzello Giovanni, Seiersen Klaus, Smith Ed, Ocanto Abrahams, Ferrer Carlos, Bentzen Søren M, Kobyzeva Daria A, Loginova Anna A, Janssens Geert O 31 May 2022, In: Radiotherapy & Oncology. 173 , p. 119-133 15 p.

Fludarabine exposure predicts outcome after CD19 CAR T-cell therapy in children and young adults with acute leukemia

Dekker Linde, Calkoen Friso G., Jiang Yilin, Blok Hilly, Veldkamp Saskia R., De Koning Coco, Spoon Maike, Admiraal Rick, Hoogerbrugge Peter, Vormoor Britta, Vormoor H. Josef, Visscher Henk, Bierings Marc, Van Der Vlugt Marieke, Van Tinteren Harm, Nijstad A. Laura, Huitema Alwin D.R., Van Der Elst Kim C.M., Pieters Rob, Lindemans Caroline A., Nierkens Stefan 12 Apr 2022, In: Blood Advances. 6 , p. 1969-1976 8 p.

Clofarabine-fludarabine-busulfan in HCT for pediatric leukemia:an effective, low toxicity, TBI-free conditioning regimen

Versluijs A. Birgitta, de Koning Coco C.H., Lankester Arjan C., Nierkens Stefan, Kollen Wouter J., Bresters Dorine, Lindemans Caroline A., Boelens Jaap Jan, Bierings Marc 22 Mar 2022, In: Blood Advances. 6 , p. 1719-1730 12 p.

Enhanced hepatic clearance of hyposialylated platelets explains thrombocytopenia in GNE-related macrothrombocytopenia

Noordermeer Tessa, van Asten Ivar, Schutgens Roger E.G., Lakerveld Anke J., Koekman Cornelis A., Hage Kay Y., Sebastian Silvie A.E., Huisman Albert, van den Heuvel Dave J., Gerritsen Hans C., Korporaal Suzanne J.A., Bierings Marc, van der Smagt Jasper J., van Gijn Marielle E., Urbanus Rolf T. 7 Mar 2022, In: Blood Advances. 6 , p. 3347-3351 5 p.

Individualised dosing of anti-thymocyte globulin in paediatric unrelated allogeneic haematopoietic stem-cell transplantation (PARACHUTE):a single-arm, phase 2 clinical trial

Admiraal Rick, Nierkens Stefan, Bierings Marc B., Bredius Robbert G.M., van Vliet Ineke, Jiang Yilin, Lopez-Yurda Marta, Versluijs A. Birgitta, Zwaan C. Michel, Lindemans Caroline A., Boelens Jaap Jan Feb 2022, In: The Lancet Haematology. 9 , p. e111-e120

HEV infection in stem cell transplant recipients-retrospective study of EBMT Infectious Diseases Working Party

Mikulska Malgorzata, Penack Olaf, Wendel Lotus, Knelange Nina, Cornelissen Jan J, Blijlevens Nicole, Passweg Jakob, Kroger Nicolaus, Bruns Anke, Koenecke Christian, Bierings Marc, Piñana José Luis, Labussiere-Wallet Helene, Ghesquieres Herve, Diaz Miguel Angel, Sampol Antonia, Averbuch Diana, de la Camara Rafael, Styczynski Jan Feb 2022, In: Bone Marrow Transplantation. 57 , p. 167-175 9 p.

Allogenic Hematopoietic Stem Cell Transplantation Is Feasible in Pediatric Patients with an Active or Recently Diagnosed Invasive Fungal Infection

Rotte Laura G.Y., Loeffen Yvette G.T., Bierings Marc B., Wolfs Tom F.W., Lindemans Caroline A. Sep 2021, In: Transplantation and Cellular Therapy. 27 , p. 781.e1-781.e5

CD4+ T-cell reconstitution predicts survival outcomes after acute graft-versus-host-disease:a dual-center validation

de Koning Coco, Prockop Susan, van Roessel Ichelle, Kernan Nancy, Klein Elizabeth, Langenhorst Jurgen, Szanto Celina, Belderbos Mirjam, Bierings Marc, Boulad Farid, Bresters Dorine, Cancio Maria, Curran Kevin, Kollen Wouter, O'Reilly Richard, Scaradavou Andromachi, Spitzer Barbara, Versluijs Birgitta, Huitema Alwin, Lindemans Caroline, Nierkens Stefan, Boelens Jaap Jan 11 Feb 2021, In: Blood. 137 , p. 848-855 8 p.

Towards homogenization of total body irradiation practices in pediatric patients across SIOPE affiliated centers. A survey by the SIOPE radiation oncology working group

Hoeben Bianca A W, Pazos Montserrat, Albert Michael H, Seravalli Enrica, Bosman Mirjam E, Losert Christoph, Boterberg Tom, Manapov Farkhad, Ospovat Inna, Milla Soraya Mico, Abakay Candan Demiroz, Engellau Jacob, Kos Gregor, Supiot Stéphane, Bierings Marc, Janssens Geert Feb 2021, In: Radiotherapy & Oncology. 155 , p. 113-119 7 p.

Population pharmacokinetics of clofarabine for allogeneic hematopoietic cell transplantation in paediatric patients

Nijstad A Laura, Nierkens Stefan, Lindemans Caroline A, Boelens Jaap Jan, Bierings Marc, Versluys A Birgitta, van der Elst Kim C M, Huitema Alwin D R 2021, In: British Journal of Clinical Pharmacology. 87 , p. 3218-3226 9 p.

All research output

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