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prof. dr. L.J. Bont

Full Professor

  • Laboratory for Translational Immunology (LTI)
  • Infectious Diseases
  • Infectious Diseases Research 2

prof. dr. L.J. Bont

Biography

Louis Bont is a Paediatrician Infectiologist at the Wilhelmina Children’s Hospital in the University Medical Center Utrecht, The Netherlands. He leads the Utrecht RSV Research Group. He is the coordinator of the Interest Group on Respiratory Infections of the European Society of Pediatric Infectious Diseases (ESPID) Research Committee. Dr. Bont is the founder and chairman of ReSViNET, an international RSV Research consortium. He has a strong interest in education of young talented researchers and founded the successful Training of Upcoming Leaders in Pediatric Science (TULIPS) career training program in the Netherlands. Dr. Bont served as advisor of the World Health Organization (WHO), the European Center of Disease Control (ECDC) and the Europarliament.

Louis Bont did his medical training at the Academic Medical Center in Amsterdam (1989-1996). He performed his PhD under the supervision of professor Jan Kimpen and professor Cobi Heijnen at the Wilhelmina Children’s Hospital (1997-2000). He was a post-doc at the Garofalo lab in Galveston, Texas (2000-2001). After returning to Utrecht, he followed the pediatric residency program followed by a pediatric infectious diseases and immunology fellowship. He have led the RSV Research Group since 2003 and became full professor in 2015.

The vision of his research is to combine clinical and basic research to decrease the global burden of RSV infection. The mission of his research group is to improve knowledge of RSV epidemiology, and to develop safe and effective therapeutic and preventive interventions.

In his work collaborate with patients is of highest importance. His work is supported by the RSV Patient Advisory Board (PAB) since 2012. The PAB has reviewed every grant application by the RSV Research Group. PAB members have been interviewed for newspapers and national television on RSV-related subjects.

Louis Bont actively participates as a teacher in the SUMMA program. In addition, he founded the TULIPS program in 2008 to train colleagues and young clinician-scientists.

Side Activities

  • Coordinator of the Interest Group on Respiratory Infections of the European Society of Pediatric Infectious Diseases (ESPID) Research Committee

    Chairman of ReSViNET, an international RSV Research Network.

    Advisor of the Europarliament

    Advisor of the World Health Organization for RSV-related programs

Fellowship and Awards

  • Full Professor (“Stimuleringshoogleraarschap”), expected in May 2015

    International Congress of Pediatric Pulmunology (CIPP) Award for Contribution to Understanding Childhood Respiratory Disease and Global Medical Education (2013)

    Dirkzwager-Assink Fonds Award by Catharijne Stichting for research on RSV bronchiolitis (2010)

    Ter Meulen Fonds lecture: It is not all asthma that wheezes. 27e Congres Nederlandse Vereniging voor Kindergeneeskunde, Veldhoven (2005)

    ESPID Fellowship Award 2001 Immunopathogenetic mechanisms of RSV infection in the mouse model (2001)

    Royal Dutch Academy of Science (Ter Meulen Fonds Stipendium). Immunopathogenetic mechanisms of RSV infection in the mouse model (2000)

Research Output (209)

Assessing the strength of evidence for a causal effect of respiratory syncytial virus lower respiratory tract infections on subsequent wheezing illness:a systematic review and meta-analysis

Brunwasser Steven M, Snyder Brittney M, Driscoll Amanda J, Fell Deshayne B, Savitz David A, Feikin Daniel R, Skidmore Becky, Bhat Niranjan, Bont Louis J, Dupont William D, Wu Pingsheng, Gebretsadik Tebeb, Holt Patrick G, Zar Heather J, Ortiz Justin R, Hartert Tina V aug 2020, In: The Lancet Respiratory Medicine. 8 , p. 795-806 12 p.

Infant RSV prophylaxis, RSV infection, and nasopharyngeal microbiota at age six years

Man Wing Ho, Scheltema Nienke, Van Houten Marlies, Nibbelke Elisabeth, Achten Niek, Arp Kayleigh, Sanders Elisabeth, Bont Louis, Bogaert Debby 28 sep 2019, In: European Respiratory Journal. 54

Update of a clinical prediction model for serious bacterial infections in preschool children by adding a host-protein-based assay:A diagnostic study

Van Houten Chantal, Van De Maat Josephine Sophia, Naaktgeboren Christiana, Bont Louis, Oostenbrink R. 1 sep 2019, In: BMJ paediatrics open. 3

Comment on Transient Tachypnea of the Newborn Is Associated With an Increased Risk of Hospitalization Due to Respiratory Syncytial Virus Bronchiolitis

van de Kam Lieke W.P.C.G., Korsten Koos, Wildenbeest Joanne G., Bont Louis J. 1 sep 2019, In: The Pediatric infectious disease journal. 38 , p. e234-e235

Fail-fast in respiratory syncytial virus vaccine development

Besteman Sjanna B., Bont Louis J. 15 aug 2019, In: American Journal of Respiratory and Critical Care Medicine. 200 , p. 410-412 3 p.

External validation and update of a prognostic model to predict mortality in hospitalized adults with RSV:A retrospective Dutch cohort study

Vos Laura M., Oosterheert Jan Jelrik, Hoepelman Andy I.M., Bont Louis J., Coenjaerts Frank E.J., Naaktgeboren Christiana A. 14 aug 2019, In: Journal of Medical Virology. 91 , p. 2117-2124 8 p.

Expert panel diagnosis demonstrated high reproducibility as reference standard in infectious diseases

van Houten Chantal B., Naaktgeboren Christiana A., Ashkenazi-Hoffnung Liat, Ashkenazi Shai, Avis Wim, Chistyakov Irena, Corigliano Teresa, Galetto Annick, Gangoiti Iker, Gervaix Alain, Glikman Daniel, Ivaskeviciene Inga, Kuperman Amir A., Lacroix Laurence, Loeffen Yvette, Luterbacher Fanny, Meijssen Clemens B., Mintegi Santiago, Nasrallah Basheer, Papan Cihan, van Rossum Annemarie M.C., Rudolph Henriette, Stein Michal, Tal Roie, Tenenbaum Tobias, Usonis Vytautas, de Waal Wouter, Weichert Stefan, Wildenbeest Joanne G., de Winter-de Groot Karin M., Wolfs Tom F.W., Mastboim Niv, Gottlieb Tanya M., Cohen Asi, Oved Kfir, Eden Eran, Feigin Paul D., Shani Liran, Bont Louis J., 1 aug 2019, In: Journal of Clinical Epidemiology. 112 , p. 20-27 8 p.

An ethics framework and practical guidance for post-trial access to an RSV maternal vaccine

Mazur Natalie I., Bont Louis J., van Delden Johannes J. M., Omer Saad B. jun 2019, In: The Lancet Respiratory Medicine. 7 , p. 474-476 3 p.

Use of the moving epidemic method (MEM) to assess national surveillance data for respiratory syncytial virus (RSV) in the Netherlands, 2005 to 2017

Vos Laura M., Teirlinck Anne C., Lozano Jose E., Vega Tomas, Donker Ge A., Hoepelman Andy I. M., Bont Louis J., Oosterheert Jan Jelrik, Meijer Adam 16 mei 2019, In: Eurosurveillance. 24 , p. 34-44

Disease severity in respiratory syncytial virus infection:Role of host genetic variation

Tahamtan Alireza, Askari Fatemeh Sana, Bont Louis, Salimi Vahid 1 mrt 2019, In: Reviews in medical virology. 29

All Research Output (209)