prof. dr. K.P.J. (Kees) Braun

prof. dr. K.P.J. (Kees) Braun

Full Professor
prof. dr. K.P.J. (Kees) Braun
  • Neurologen

Research Programs




Kees Braun obtained his Medical Degree at Utrecht University in January 1992. He specialized in Neurology (registered in 2000) and Paediatric Neurology (registered in 2002) in the UMC Utrecht. In 2000 he obtained his PhD degree on a thesis entitled “Magnetic Resonance Spectroscopy in Hydrocephalus. He was appointed as staff neurologist in 2000 and paediatric neurologist in 2002. Since 2011 he is head of Paediatric Neurology/Neurosurgery.  In May 2012 he was appointed as a full professor of Paediatric Neurology.

His clinical and scientific areas of expertise are: refractory paediatric epilepsy, epilepsy surgery,  imaging in epilepsy, and childhood arteriopathic stroke, in particular moyamoya treatment.

He coordinates epilepsy research in the  UMCU Brain center. The epilepsy research projects he is personally involved in  focus on the effects of focal epilepsy on the brain in animal models and patients (structural and functional integrity and network analysis); seizure- and cognitive outcome after paediatric epilepsy surgery; postoperative antiepileptic drug withdrawal; ESES treatment; stress and epilepsy; and epileptic focus detection in surgical candidates.

Kees Braun currently is president of the Dutch Society of Paediatric Neurology and of the organizing committee of the 2016 world congress of child neurology (ICNC) in Amsterdam. He is member of the European Task Force for Epilepsy Surgery in Children (U-Task), the European Network for Epilepsy Research (ENER), and work-package leader of the EU-funded E-PILEPSY project.

Research line

Refractory epilepsy

Most recent key publications

1: Boshuisen K, Arzimanoglou A, Cross JH, Uiterwaal CS, Polster T, van Nieuwenhuizen O, Braun KP; for the TimeToStop study Group. Timing of antiepileptic drug withdrawal and long-term seizure outcome after paediatric epilepsy surgery (TimeToStop): a retrospective observational study. Lancet Neurol 2012:11:784-791
2: Van Campen JS, Jansen FE, Pet MA, Otte WM, Hillegers MH, Joels M, Braun KP. Relation between stress-precipitated seizures and the stress response in childhood epilepsy. Brain 2015;138:2234-2248
3: Lamberink HJ, Boshuisen K, van Rijen PC, Gosselaar PH, Braun KP. Changing profiles of pediatric epilepsy surgery candidates over time: a nationwide single-center experience from 1990 to 2011. Epilepsia 215;56:717-725
4: Boshuisen K, van Schooneveld MM, Uiterwaal CS, Cross JH, Harrison S, Polster T, Daehn M, Djimjadi S, Yalnizoglu D, Turanli G, Sassen R, Hoppe C, Kuczaty S, Barba C, Kahane P, Schubert-Bast S, Reuner G, Bast T, Strobl K, Mayer H, de Saint-Martin A, Seegmuller C, Laurent A, Arzimanoglou A, Braun KP, for the TimeToStop cognitive outcome study group. Intelligence quotient improves after antiepileptic drug withdrawal following pediatric epilepsy surgery. Ann Neurol 2015;78:104-114
5: Braun KPJ, Bulder MMM, Chabrier S, Kirkham FJ, Uiterwaal CSP, Tardieu M, Sebire G. Longitudinal vascular imaging in 79 children with ischemic stroke and unilateral intracranial arteriopathy. Brain 2009;132:544-557

Side Activities

As mentioned in the Biography.

Fellowship and Awards

1: Recipient of the first “Patrick Hanlo Award”, March 17 2009
2: Personal investment grant for epilepsy research by the Dutch National Epilepsy Fund
3: Recipient of the “Gerlach Cerfontaine Fellowship” of the Catharijne Foundation, UMCU, 1998-2000, for the PhD project “Magnetic Resonance Spectroscopy in Hydrocephalus”
4: Recipient of several research grants from e.g. the Dutch Epilepsy Fund, Johanna Children’s Fund, and Wilhelmina Research Fund.

Research Output (279)

Gastrointestinal and eating problems in SCN1A-related seizure disorders

Minderhoud C A, Postma A, Jansen F E, Verhoeven J S, Schrijver J J, Goudswaard J, Andreae G, Otte W M, Braun K P J, Brilstra E H 29 Jul 2023, In: Epilepsy & Behavior. 146 8 p.

Anesthesia Depresses Cerebrovascular Reactivity to Acetazolamide in Pediatric Moyamoya Vasculopathy

Deckers Pieter T, Siero Jeroen CW, Mensink Maarten O, Kronenburg Annick, Braun Kees P J, van der Zwan Albert, Bhogal Alex A Jul 2023, In: Journal of Clinical medicine. 12

Toward responsible clinical n-of-1 strategies for rare diseases

Defelippe Victoria M, J M W van Thiel Ghislaine, Otte Willem M, Schutgens Roger E G, Stunnenberg Bas, Cross Helen J, O'Callaghan Finbar, De Giorgis Valentina, Jansen Floor E, Perucca Emilio, Brilstra Eva H, Braun Kees P J 24 Jun 2023, In: Drug Discovery Today. 28 9 p.

The importance of discriminative power rather than significance when evaluating potential clinical biomarkers in epilepsy research

Slinger Geertruida, Stevelink Remi, van Diessen Eric, Braun Kees P J, Otte Willem M Jun 2023, In: Epileptic Disorders. 25 , p. 285-296 12 p.

Antiseizure Medication Withdrawal Practice Patterns:A Survey among Members of the American Academy of Neurology and EpiCARE

Terman Samuel W., Slinger Geertruida, Rheaume Carol E., Haque Anisa S., Smith Shawna N., Van Griethuysen Renate, Van Asch Charlotte J.J., Otte Willem M., Burke James F., Braun Kees P.J. 13 Feb 2023, In: Neurology: Clinical Practice. 13

Antiseizure medication withdrawal risk estimation and recommendations:a survey of American Academy of Neurology and EpiCARE members

Terman Samuel W, van Griethuysen Renate, Rheaume Carole E, Slinger Geertruida, Haque Anisa S, Smith Shawna N, Kerr Wesley T, van Asch Charlotte, Otte Willem M, Ferreira-Atuesta Carolina, Galovic Marian, Burke James F, Braun Kees Pj 31 Jan 2023, In: Epilepsia Open. 8 , p. 386-398 13 p.

Frequency of and factors associated with antiseizure medication discontinuation discussions and decisions in patients with epilepsy:a multicenter retrospective chart review

Terman Samuel W, Slinger Geertruida, Koek Adriana, Skvarce Jeremy, Springer Mellanie V, Ziobro Julie M, Burke James F, Otte Willem M, Thijs Roland D, Braun Kees Pj 24 Jan 2023, In: Epilepsia Open. 8 , p. 371-385 15 p.

Assessment of aortic and cerebral haemodynamics and vascular brain injury with 3 and 7 T magnetic resonance imaging in patients with aortic coarctation

Meijs Timion A., Van Tuijl Rick J., Van Den Brink Hilde, Weaver Nick A., Siero Jeroen C.W., Van Der Worp H. Bart, Braun Kees P.J., Leiner Tim, De Jong Pim A., Zwanenburg Jaco J.M., Doevendans Pieter A., Voskuil Michiel, Grotenhuis Heynric B. 11 Jan 2023, In: European heart journal open. 3 10 p.

Not surgical technique, but etiology, contralateral MRI, prior surgery, and side of surgery determine seizure outcome after pediatric hemispherotomy

Ramantani Georgia, Bulteau Christine, Cserpan Dorottya, Otte Willem M., Dorfmüller Georg, Cross J. Helen, Zentner Josef, Tisdall Martin, Braun Kees P.J. 2023, In: Epilepsia. 64 , p. 1214-1224 11 p.

Clinical Outcome, Cognition, and Cerebrovascular Reactivity after Surgical Treatment for Moyamoya Vasculopathy:A Dutch Prospective, Single-Center Cohort Study

Deckers Pieter Thomas, Kronenburg Annick, van den Berg Esther, van Schooneveld Monique M., Vonken Evert Jan P.A., Otte Willem M., van Berckel Bart N.M., Yaqub Maqsood, Klijn Catharina J.M., van der Zwan Albert, Braun Kees P.J. 2 Dec 2022, In: Journal of Clinical medicine. 11 , p. 1-23

All research output

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