dr. L.B. Creemers
dr. L.B. Creemers
- Department of Orthopaedics
Research Programs
Biography
Biography
Dr Creemers studied Biomedical Sciences in Leiden and has worked in several research areas, including spermatogenic stem cells, (periodontal) ligament, tendon and bone. Since 2005 her focus is on cartilage and intervertebral disc research with a special interest in biomaterials-based local delivery approaches for regeneration and treatment of inflammation. Delivery includes small molecules, proteins, peptides and nucleic acids, research approaches involve biological effects, pharmacokinetics and imaging,using in vitro and in vivo models, the latter in close collaboration with the dept of Companion Animals at the Fac Veterinary Medicine. She is author on over 90 peer-reviewed publications and has in the past years been involved in several projects on local delivery, including BMM IdiDAS (9.2 M€; PI) targeting disc degeneration, BMM-OAcontrol on osteoarthritis and LSH –ArIADNE (1.2 M€;PI), where local delivery of anti-inflammatory mediators in osteoarthritis and intervertebral disc degeneration is further being taken towards clinical translation. In addition she is involved in H2020 ITN-TargetCaRe on targeted delivery in intervertebral disc and cartilage regeneration.
Side Activities
Chair Science and Research Committee (Wetenschapscommissie) Division Surgical Specialties UMCU, member International Reviewer panel eCM, member several research organisations (AO, ICRS, OARSI, NVMB, NBTE)
Fellowship and Awards
Co-awardee ‘Mathijsen award’ to R Custers (2011) and KG Auw Yang (2009) by the Dutch Orthopaedic Society for the best PhD thesis
Research Output (154)
Tellegen Anna R, Rudnik-Jansen Imke, Utomo Lizette, Versteeg Sabine, Beukers Martijn, Maarschalkerweerd Roelof, van Zuilen Dick, van Klaveren Nicoline J, Houben Kaat, Teske Erik, René van Weeren P, Karssemakers-Degen Nina, Mihov George, Thies Jens, Eijkelkamp Niels, Creemers Laura B, Meij Björn P, Tryfonidou Marianna A 5 Dec 2022, In: Osteoarthritis and Cartilage. 31 , p. 351-362 12 p.
Pontes Adriano P., Welting Tim J.M., Rip Jaap, Creemers Laura B. Dec 2022, In: Pharmaceutics. 14 , p. 1-25
Du Jie, Garcia João P., Bach Frances C., Tellegen Anna R., Grad Sibylle, Li Zhen, Castelein René M., Meij Björn P., Tryfonidou Marianna A., Creemers Laura B. Nov 2022, In: Journal of Orthopaedic Translation. 37 , p. 23-36 14 p.
Laagland Lisanne T., Bach Frances C., Creemers Laura B., Le Maitre Christine L., Poramba-Liyanage Deepani W., Tryfonidou Marianna A. Sep 2022, In: JOR spine. 5 , p. 1-13
Zerrillo Luana, Gigliobianco Maria Rosa, D’atri Domenico, Garcia Joao Pedro, Baldazzi Fabio, Ridwan Yanto, Fuentes Gastón, Chan Alan, Creemers Laura B., Censi Roberta, Martino Piera Di, Cruz Luis J. 1 Jul 2022, In: Nanomaterials. 12 , p. 1-17
Jorquera-Cordero Carla, Lara Pablo, Cruz Luis J., Schomann Timo, van Hofslot Anna, de Carvalho Thaís Gomes, Guedes Paulo Marcos Da Matta, Creemers Laura, Koning Roman I., Chan Alan B., Junior Raimundo Fernandes de Araujo 17 May 2022, In: Pharmaceutics. 14 , p. 1-17
Wesdorp Marinus A., Capar Serdar, Bastiaansen-Jenniskens Yvonne M., Kops Nicole, Creemers Laura B., Verhaar Jan A.N., Van Osch Gerjo J.V.M., Wei Wu May 2022, In: American Journal of Sports Medicine. 50 , p. 1668-1678 11 p.
Muenzebrock Katrin Agnes, Kersten Valerie, Alblas Jacqueline, Creemers Laura B 3 Mar 2022, In: Frontiers in bioengineering and biotechnology. 10 , p. 1-17
Wiersema Tijn, Tellegen Anna R., Beukers Martijn, van Stralen Marijn, Wouters Erik, van de Vooren Mandy, Woike Nina, Mihov George, Thies Jens C., Creemers Laura B., Tryfonidou Marianna A., Meij Björn P. Aug 2021, In: Pharmaceutics. 13 , p. 1-17
D'Atri D., Zerrillo L., Garcia J., Oieni J., Lupu-Haber Y., Schomann T., Chan A., Cruz L. J., Creemers L. B., Machluf Marcelle 17 May 2021, In: Journal of controlled release : official journal of the Controlled Release Society. 337 , p. 472-481 10 p.