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prof. dr. J. Hendrikse

prof. dr. J. Hendrikse

Full Professor
prof. dr. J. Hendrikse
  • Researchgr. Neuroradiologie

Research Programs

Brain

Biography

Biography

The overall aim of prof. Hendrikse’s research is to understand the cause of ischemic stroke with a focus on the three P’s: Pipes (vessel and vessel walls), Perfusion (CBF and reserve capacity) and Parenchyma (brain tissue and tissue changes/infarcts). After his PhD in 2004 he has created a new research field with technical development and clinical applications of MR methods of cerebral perfusion (so called arterial spin labeling MRI) and intracranial vessel wall imaging. His original MR research is recognized by the international research field with European grants (FP7, Biocog; WP leader) and personal national excellence grants (ERC-StG, VIDI, VENI, Heart association, Technical Research Council), chairmanship of international (ISMRM) perfusion study group, steering committee member of Carotid Stenosis Triallists Collaboration (CSTC), invited lectures, reviews, white papers and book chapters. 22 of his publications are within international collaborations (including Johns Hopkins University and Vanderbilt University, USA). He has over 30 publications within the field of 7T MRI brain imaging method developments. In the radiology and neurovascular research arena ‘RADIOLOGY and ‘STROKE’ are leading journals: he has over 30 publications in these journals. He is the first radiologist awarded with a VIDI grant and an ERC-StG. The focus of his research group is to understand the relation between the ‘3Ps’: pipes (arterial vasculature), perfusion and parenchyma (brain tissue damage) by using innovative imaging methods. Early 2017 he was appointed Chairman of Radiology and Nuclear Medicine UMC Utrecht.

 

Research line

Brain MRI: Pipes, Perfusion, Parenchyma

Most recent key publications

1: Dieleman N, Van der Kolk AG. Hendrikse J. MR intracranial vessel wall imaging: current prospects and future directions. Circulation. 2014 Jul 8;130(2):192-201
2: De Vis JB, Petersen ET, Bhogal A, Hartkamp NS, Klijn CJ, Kappelle LJ, Hendrikse J. Calibrated MRI to evaluate cerebral hemodynamics in patients with an internal carotid artery occlusion. J Cereb Blood Flow Metab. 2015 Jun;35(6):1015-23
3: Van der Kolk AG, Zwanenburg JJ, Brundel M, Biessels GJ, Visser F, Luijten PR, Hendrikse J. Distribution and natural course of intracranial vessel wall lesions in patients with ischemic stroke or TIA at 7.0 Tesla MRI. Eur Radiol. 2015 Jun;25(6):1692-700
4: De Rotte AA, Truijman MT, van Dijk AC, Liem MI, Schreuder FH, van der Kolk AG, de Kruijk JR, Daemen MJ, van der Steen AF, de Borst GJ, Luijten PR, Nederkoorn PJ, Kooi ME, van der Lugt A, Hendrikse J. Plaque components in symptomatic moderately stenosed carotid arteries related to cerebral infarcts: the plaque at RISK study. Stroke. 2015 Feb;46(2):568-71
5: Hendrikse J, Van der Grond J, Lu H, Van Zijl PCM, Golay X. Flow territory mapping of the cerebral arteries with MRI. Stroke. 2004;35:882-887

Side Activities

ZonMW Veni-subsidiereviewer 2018, 2019 en 2020 

 

Fellowship and Awards

1: ERC-StG
2: VENI and VIDI
3: FP7-WP-Leader
4: Dutch Heart Association
5: STW/Technical Research Council

Research Output (312)

Dolichoarteriopathies of the extracranial internal carotid artery:The Plaque At RISK study

Dilba Kristine, van Dam-Nolen Dianne H K, Crombag Geneviève A J C, van der Kolk Anja G, Koudstaal Peter J, Nederkoorn Paul J, Hendrikse Jeroen, Kooi Marianne Eline, van der Steen Antonius F W, Wentzel Jolanda J, van der Lugt Aad, Bos Daniel sep 2021, In: European Journal of Neurology. 28 , p. 3133-3138 6 p.

Lipoprotein(a) levels and atherosclerotic plaque characteristics in the carotid artery:The Plaque at RISK (PARISK) study

van Dam-Nolen Dianne H K, van Dijk Anouk C, Crombag Geneviève A J C, Lucci Carlo, Kooi M Eline, Hendrikse Jeroen, Nederkoorn Paul J, Daemen Mat J A P, van der Steen Antonius F W, Koudstaal Peter J, Kronenberg Florian, Roeters van Lennep Jeanine E, Mulder Monique T, van der Lugt Aad jul 2021, In: Atherosclerosis. 329 , p. 22-29 8 p.

Quantitative magnetic resonance imaging of the brachial plexus shows specific changes in nerve architecture in chronic inflammatory demyelinating polyneuropathy, multifocal motor neuropathy and motor neuron disease

van Rosmalen Marieke, Goedee H Stephan, Derks Rosina, Asselman Fay-Lynn, Verhamme Camiel, de Luca Alberto, Hendrikse J, van der Pol W Ludo, Froeling Martijn 27 mei 2021, In: European Journal of Neurology. 28 , p. 2716-2726 11 p.

Preoperative MRI brain phenotypes are related to postoperative delirium in older individuals

Kant Ilse M J, Slooter Arjen J C, Jaarsma-Coes Myriam, van Montfort Simone J T, Witkamp Theo D, Pasma Wietze, Hendrikse Jeroen, de Bresser Jeroen, mei 2021, In: Neurobiology of Aging. 101 , p. 247-255 9 p.

Genotype-phenotype correlation in pseudoxanthoma elasticum

Bartstra Jonas W., Risseeuw Sara, de Jong Pim A., van Os Bram, Kalsbeek Lianne, Mol Chris, Baas Annette F., Verschuere Shana, Vanakker Olivier, Florijn Ralph J., Hendrikse Jeroen, Mali Willem, Imhof Saskia, Ossewaarde-van Norel Jeannette, van Leeuwen Redmer, Spiering Wilko mei 2021, In: Atherosclerosis. 324 , p. 18-26 9 p.

Association of White Matter Hyperintensity Markers on MRI and Long-term Risk of Mortality and Ischemic Stroke:The SMART-MR Study

Ghaznawi Rashid, Geerlings Mirjam, Jaarsma-Coes Myriam, Hendrikse Jeroen, de Bresser Jeroen, 16 mrt 2021, In: Neurology. 96 , p. e2172-e2183

Absence of Consistent Sex Differences in Outcomes From Symptomatic Carotid Endarterectomy and Stenting Randomized Trials

Howard Virginia J, Algra Ale, Howard George, Bonati Leo H, de Borst Gert J, Bulbulia Richard, Calvet David, Eckstein Hans-Henning, Fraedrich Gustav, Greving Jacoba P, Halliday Alison, Hendrikse Jeroen, Jansen Olav, Brown Martin M, Mas Jean-Louis, Ringleb Peter A, Brott Thomas G, feb 2021, In: Stroke. 52 , p. 416-423 8 p.

Subvoxel vessel wall thickness measurements of the intracranial arteries using a convolutional neural network

van Hespen Kees M, Zwanenburg Jaco J M, Hendrikse Jeroen, Kuijf Hugo J jan 2021, In: Medical Image Analysis. 67 , p. 1-10

Arterial Remodeling of the Intracranial Arteries in Patients With Hypertension and Controls:A Postmortem Study

van Hespen Kees M, Mackaaij Claire, Waas Ingeborg S E, de Bree Marloes P, Zwanenburg Jaco J M, Kuijf Hugo J, Daemen Mat J A P, Hendrikse Jeroen, Hermkens Dorien M A jan 2021, In: Hypertension (Dallas, Tex. : 1979). 77 , p. 135-146 12 p.

Quantification of disease progression in spinal muscular atrophy with muscle MRI-a pilot study

Otto Louise A M, Froeling Martijn, van Eijk Ruben P A, Asselman Fay-Lynn, Wadman Renske, Cuppen Inge, Hendrikse Jeroen, van der Pol W-Ludo 2021, In: NMR in Biomedicine. 34

All research output

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