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prof. dr. S.M.A. Lens

prof. dr. S.M.A. Lens

Full Professor

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Research Output (84)

The forkhead transcription Factor FocO regulates transcription of p27Kip1 and Bim in response to IL-2 1

Stahl M., Dijkers P.F., Kops G.J.P.L., Lens S.M.A., Coffer P.J, Burgering B.M.T., Medema R.H. 2002, In: Journal of Immunology. 168 , p. 5024-5031 8 p.

Maturation of marginal zone and follicular B cells requires B cell activating factor of the tumor necrosis factor family and is independent of B cell maturation antigen

Schneider P, Takatsuka H, Wilson A, Mackay F, Tardivel A, Lens S, Cachero TG, Finke D, Beermann F, Tschopp J 3 Dec 2001, In: Journal of Experimental Medicine. 194 , p. 1691-1697

NF-kappa B signals induce the expression of c-FLIP

Micheau O, Lens S, Gaide O, Alevizopoulos K, Tschopp J Aug 2001, In: Molecular and Cellular Biology. 21 , p. 5299-5305

Protein kinase A regulates expression of p27 (kip1) and cyclin D3 to suppress proliferation of leukemic T cell lines

van Oirschot - Hermans B.A., Stahl M., Lens S.M.A., Medema R.H. 2001, In: Journal of Biological Chemistry. 276 , p. 33854-33860 7 p.

Fas engagement induces the maturation of dendritic cells (DCs), the release of interleukin (IL)-1 beta, and the production of interferon gamma in the absence of IL-12 during DC-T cell cognate interaction: A new role for Fas ligand in inflammatory responses

Rescigno M, Piguet V, Valzasina B, Lens S, Zubler R, French L, Kindler V, Tschopp J, Ricciardi-Castagnoli P 4 Dec 2000, In: Journal of Experimental Medicine. 192 , p. 1661-1668

TGF-beta induces the expression of the FLICE-inhibitory protein and inhibits Fas-mediated apoptosis of microglia

Schlapbach R, Spanaus KS, Malipiero U, Lens S, Tasinato A, Tschopp J, Fontana A Dec 2000, In: European Journal of Immunology. 30 , p. 3680-3688

Cytolytic mechanisms and expression of activation-regulating receptors on effector-type CD8+CD45RA+CD27- human T cells

Baars P A, Ribeiro Do Couto L M, Leusen J H, Hooibrink B, Kuijpers T W, Lens S M, van Lier R A 15 Aug 2000, In: Journal of Immunology. 165 , p. 1910-7 8 p.

Aberrant expression and reverse signalling of CD70 on malignant B cells

Lens SMA, Drillenburg P, den Drijver BFA, van Schijndel G, Pals ST, van Lier RAW, van Oers MHJ Aug 1999, In: British Journal of Haematology. 106 , p. 491-503

Control of lymphocyte function through CD27-CD70 interactions

Lens SMA, Tesselaar K, van Oers MHJ, van Lier RAW Dec 1998, In: Semin Immunology. 10 , p. 491-499

Dissection of pathways leading to antigen receptor-induced and Fas/CD95-induced apoptosis in human B cells

Lens SMA, den Drijver BFA, Potgens AJG, Tesselaar K, van Oers MHJ, van Lier RAW 15 Jun 1998, In: Journal of Immunology. 160 , p. 6083-6092 10 p.

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