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prof. dr. ir. J. (Jos) Malda

prof. dr. ir. J. (Jos) Malda

Full Professor
prof. dr. ir. J. (Jos) Malda
  • Department of Orthopaedics

Biography

Biography

  1. Our research group focuses on biofabrication and biomaterials design, in particular for the regeneration of (osteo) chondral defects. We are developing novel biofabriaction strategies, as well and “bioinks” for 3D printing. These hydrogel-based “inks” are both designed to drive specific differentiation of the embedded and/or endogenous cells, as well as to allow fabrication with high shape fidelity in order to generate constructs that are a blueprint of the real tissue. In addition, we are adopting bioreactor technology to mature the generated tissue constructs. Finally, approaches towards the translation of the constructs in veterinary (equine) and human clinics are pursued, including its use as an in vitro platform for testing. 

    Areas of interest 
    - Joint regeneration 
    - Biofabrication 

    - Biomaterial development

    - Bioreactors

    - Extracellular matrix-derived scaffolds 

    - Nutrient limitation 

Side Activities

Hoogleraar Biofabrication in Translational Regenerative Medicine (0,7FTE), Afdeling Orthopaedie, UMC Utrecht
Secretary General van de International Cartilage Repair and Joint Restoration Society (ICRS; 2022-2023)
Voormalig President van de International Society for Biofabrication (ISBF; 2014-2018)
Board member International Society for Biofabrication (ISBF; 2014-2022)
Scientific Advisor, SentryX B.V.

Fellowship and Awards

Anna Prize 2017, Anna Foundation and Nederlandse Orthopaedische Vereniging

Nanonica Prize 2015 for the breakthrough of the year in the field of nanotechnology, Nanonica Europe

ERC Consolidator Grant ERC-2014-CoG_647426

NWO Veni FellowshipPrinten van levend kraakbeen 

Research Output (228)

Tissue-specific melt electrowritten polymeric scaffolds for coordinated regeneration of soft and hard periodontal tissues

Daghrery Arwa, Ferreira Jessica A., Xu Jinping, Golafshan Nasim, Kaigler Darnell, Bhaduri Sarit B., Malda Jos, Castilho Miguel, Bottino Marco C. Jan 2023, In: Bioactive Materials. 19 , p. 268-281 14 p.

Human adult, pediatric and microtia auricular cartilage harbor fibronectin-adhering progenitor cells with regenerative ear reconstruction potential

Otto Iris A., Bernal Paulina Nuñez, Rikkers Margot, van Rijen Mattie H.P., Mensinga Anneloes, Kon Moshe, Breugem Corstiaan C., Levato Riccardo, Malda Jos 16 Sep 2022, In: iScience. 25 , p. 1-21

Robust gelatin hydrogels for local sustained release of bupivacaine following spinal surgery

Steverink Jasper G., van Tol Floris R., Oosterman Bas J., Vermonden Tina, Verlaan Jorrit Jan, Malda Jos, Piluso Susanna 1 Jul 2022, In: Acta Biomaterialia. 146 , p. 145-158 14 p.

Bioink with cartilage-derived extracellular matrix microfibers enables spatial control of vascular capillary formation in bioprinted constructs

Terpstra Margo L., Li Jinyu, Mensinga Anneloes, de Ruijter Mylène, van Rijen Mattie H.P., Androulidakis Charalampos, Galiotis Costas, Papantoniou Ioannis, Matsusaki Michiya, Malda Jos, Levato Riccardo Jul 2022, In: Biofabrication. 14 , p. 1-20

SILK-BASED MATERIALS TO CREATE HIGH RESOLUTION THREE-DIMENSIONAL STRUCTURES USING ELECTROHYDRODYNAMIC PRINTING

Viola Martina, Piluso Susanna, Mihajlovic Marko, Malda Jos, Castilho Miguel, Vermonden Tina Apr 2022, In: Tissue Engineering. Part A. 28 , p. S110-S110

PROGENITOR CELLS DERIVED FROM HEALTHY AND OSTEOARTHRITIC HUMAN CARTILAGE SHOW POTENTIAL FOR CARTILAGE TISSUE ENGINEERING

Rikkers Margot, Korpershoek Jasmijn, Levato Riccardo, Malda Jos, Vonk Lucienne Apr 2022, In: Tissue Engineering. Part A. 28 , p. S104-S104

NEXT GENERATION BIOENGINEERED HUMAN MYOCARDIUM

van Mil Alain, Castilho Miguel, Chirico Nino, Ainsworth Madison J., Dokter Inge, Maas Renee G. C., Buikema Jan Willem, Malda Jos, Sluijter Joost P. G. Apr 2022, In: Tissue Engineering. Part A. 28 , p. S430-S431

HIGH-SPEED VOLUMETRIC BIOPRINTING APPROACH FOR BIOFABRICATION OF COMPLEX LIVING TISSUE STRUCTURES

Bernal Paulina Nunez, Delrot Paul, Loterie Damien, Li Yang, Malda Jos, Moser Christophe, Levato Riccardo Apr 2022, In: Tissue Engineering. Part A. 28 , p. S150-S150

DUAL-FUNCTIONALIZED VISIBLE-LIGHT RESPONSIVE GELATIN BIOINK AS CARTILAGE BINDING GLUE AND MATRIX FOR 3D CHONDRAL REGENERATION

Abinzano Florencia, Lim Khoon, Bernal Paulina Nunez, Roca Pau Atienza, Sanchez Ane Albillos, Otto Iris, Matsusaki Michiya, Woodfield Tim, Malda Jos, Levato Riccardo Apr 2022, In: Tissue Engineering. Part A. 28 , p. S222-S223

A 3D-PRINTED BONE IMPLANT FOR HIP DYSPLASIA TREATMENT: COMBINING SHAPE AND MECHANICAL FUNCTION IN A FULLY RESORBABLE IMPLANT

Golafshan Nasim, Willemsen Koen, Weinans Harrie, van der Wal Bart C. H., Malda Jos, Castilho Miguel Apr 2022, In: Tissue Engineering. Part A. 28 , p. S440-S440

All research output

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