prof. dr. N.F. Ramsey

prof. dr. N.F. Ramsey

Full Professor
prof. dr. N.F. Ramsey
  • Neurology & Neurosurgery

Research Programs




Nick Ramsey has a degree in Psychology and a PhD in neuro-psychopharmacology, both from the university of Utrecht (Netherlands). He became a specialist in cognitive neuroimaging in the US (National Institutes of Health), and applies modern techniques, including high-field (7 Tesla) fMRI and intracranial EEG, to questions on working memory, language, and sensorimotor function. His primary goal is to acquire and translate neuro-scientific insights to patients with neurological and psychiatric disorders, with a focus on brain-computer interfacing (BCI). He is full professor in cognitive neuroscience at the department of neurology and neurosurgery of the UMC Utrecht since 2007. He has been awarded several personal grants including a VIDI (NWO, 2002) for elucidating working memory, a VICI (NWO, 2006) and later a European ERC Advanced grant for developing intracranial BCI concepts for paralyzed people. The BCI research resulted in a world-wide first fully implanted BCI for home use, implanted in a locked-in patient with ALS in 2015. Current research aims to develop and implement the next generation BCI implants, for enabling people with communication disorders to speak again. He has co-founded, and is the current President of, the international brain-Computer Interface. He has also been awarded a STW Valorisation grant (phase 1 & 2) for starting a spin-off company (BrainCarta) to provide Clinical fMRI reports to clinicians. He has supervised over 20 PhD students and has (co)authored over 180 peer-reviewed publications.

Research line

Brain-Computer Interface, Human Brain Function, Neurotechnology, Translational Neuroscience

Key publications

 1: Ramsey NF, Salari E, Aarnoutse EJ, Vansteensel MJ, Bleichner MB and Freudenburg ZV (2017) Decoding spoken phonemes from sensorimotor cortex with High-Density ECoG grids. Neuroimage (in press)

2: Bruurmijn LCM, Pereboom IPL, Vansteensel MJ, Raemaekers MAH and Ramsey NF (2017) Preservation of hand movement representation in the sensorimotor areas of amputees. Brain 140(12):3166-3178

3: Berezutskaya J, Freudenburg ZV, Güçlü U, van Gerven MAJ, Ramsey NF (2017) Neural tuning to low-level features of speech throughout the perisylvian cortex. J Neurosci (in press)

4: Vansteensel MJ, Pels EGM, Bleichner MG, Branco MP, Denison T, Freudenburg ZV, Gosselaar P, Leinders S, Ottens TH, Van Den Boom MA, Van Rijen PC, Aarnoutse EJ, Ramsey NF (2016) Fully Implanted Brain–Computer Interface in a Locked-In Patient with ALS. N Engl J Med 375:2060-2066

5: Branco MP, Freudenburg ZV, Aarnoutse EJ, Bleichner MG, Vansteensel MJ, Ramsey NF (2016) Decoding hand gestures from primary somatosensory cortex using high-density ECoG. Neuroimage 147:130-142

6: Vansteensel MJ, Bleichner MG, Freudenburg ZV, Hermes D, Aarnoutse EJ, Leijten FS, Ferrier CH, Jansma JM, Ramsey NF (2014) Spatiotemporal characteristics of electrocortical brain activity during mental calculation. Hum Brain Mapp. 35(12):5903-20.

7: Ramsey NF, Aarnoutse EJ, Vansteensel MJ (2014) Brain implants for substituting lost motor function: state of the art and potential impact on lives of motor-impaired seniors. Gerontology 60(4): 366-72

Side Activities

CSO & Founder of startup (unpaid), Braincarta BV

Scientific Advisor to Wyss Center For Bio And Neuroengineering

Fellowship and Awards

Fogarty Fellowship at the National Institute in Alcohol abuse and Alcoholism (1992)

Fogarty Fellowship at the National Institute of Mental Health (1994)

SIGO Prize for interdisciplinary behavioral science (2018)

Research Output (266)

Direct speech reconstruction from sensorimotor brain activity with optimized deep learning models

Berezutskaya Julia, Freudenburg Zachary V, Vansteensel Mariska J, Aarnoutse Erik J, Ramsey Nick F, van Gerven Marcel A J 1 Oct 2023, In: Journal of Neural Engineering. 20 , p. 1-25 25 p.

Brain implants that enable speech pass performance milestones

Ramsey Nick F, Crone Nathan E 31 Aug 2023, In: Nature. 620 , p. 954-955 2 p.

Using fMRI to localize target regions for implanted brain-computer interfaces in locked-in syndrome

Leinders Sacha, Vansteensel Mariska J, Piantoni Giovanni, Branco Mariana P, Freudenburg Zac V, Gebbink Tineke A, Pels Elmar G M, Raemaekers Mathijs A H, Schippers Anouck, Aarnoutse Erik J, Ramsey Nick F 18 Aug 2023, In: Clinical Neurophysiology. 155 , p. 1-15 15 p.

Precise Spatial Tuning of Visually Driven Alpha Oscillations in Human Visual Cortex

Yuasa Kenichi, Groen Iris I A, Piantoni Giovanni, Montenegro Stephanie, Flinker Adeen, Devore Sasha, Devinsky Orrin, Doyle Werner, Dugan Patricia, Friedman Daniel, Ramsey Nick, Petridou Natalia, Winawer Jonathan 12 Jul 2023, p. 1-40

Reliability and validity of DTI-based indirect disconnection measures

Smits A R, van Zandvoort M J E, Ramsey N F, de Haan E H F, Raemaekers M Jan 2023, In: NeuroImage. Clinical. 39

The impact of etiology in lesion-symptom mapping - A direct comparison between tumor and stroke

van Grinsven E E, Smits A R, van Kessel E, Raemaekers M A H, de Haan E H F, Huenges Wajer I M C, Ruijters V J, Philippens M E P, Verhoeff J J C, Ramsey N F, Robe P A J T, Snijders T J, van Zandvoort M J E Jan 2023, In: NeuroImage. Clinical. 37

Nine decades of electrocorticography:A comparison between epidural and subdural recordings

Branco Mariana P, Geukes Simon H, Aarnoutse Erik J, Ramsey Nick F, Vansteensel Mariska J 2023, In: European Journal of Neuroscience. 57 , p. 1260-1288 29 p.

Advances in human intracranial electroencephalography research, guidelines and good practices

Mercier Manuel R, Dubarry Anne-Sophie, Tadel François, Avanzini Pietro, Axmacher Nikolai, Cellier Dillan, Vecchio Maria Del, Hamilton Liberty S, Hermes Dora, Kahana Michael J, Knight Robert T, Llorens Anais, Megevand Pierre, Melloni Lucia, Miller Kai J, Piai Vitória, Puce Aina, Ramsey Nick F, Schwiedrzik Caspar M, Smith Sydney E, Stolk Arjen, Swann Nicole C, Vansteensel Mariska J, Voytek Bradley, Wang Liang, Lachaux Jean-Philippe, Oostenveld Robert 15 Oct 2022, In: NeuroImage. 260


van Grinsven E. E., Smits A. R., van Kessel E., Raemaekers M., de Haan E. H. F., Huenges-Wajer I. M. C., Ruijters V. J., Philippens M. E. P., Verhoeff J. J. C., Ramsey N. F., Robe P. A. J. T., Snijders T. J., van Zandvoort M. J. E. 5 Sep 2022, In: Neuro-oncology. 24 , p. ii24

Temporal dynamics of neural responses in human visual cortex

Groen Iris I A, Piantoni Giovanni, Montenegro Stephanie, Flinker Adeen, Devore Sasha, Devinsky Orrin, Doyle Werner, Dugan Patricia, Friedman Daniel, Ramsey Nick, Petridou Natalia, Winawer Jonathan 19 Aug 2022, In: The Journal of neuroscience : the official journal of the Society for Neuroscience. 42 , p. 7562-7580 19 p.

All research output

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