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dr. G. Rozhnova

dr. G. Rozhnova

Associate Professor
dr. G. Rozhnova
  • Julius Center, dept. Epidemiology & Health Economics

Research Programs

Infection & Immunity

Biography

Biography

Dr. Ganna Rozhnova is an Associate Professor in Infectious Disease Modeling at the University Medical Center Utrecht in the Netherlands and the Faculty of Sciences at the University of Lisbon in Portugal. She is a group leader at the BioISI—Biosystems & Integrative Sciences Institute in Lisbon. Her research focuses on applying infectious disease modeling to address questions and support evidence-based policymaking in public health. Her mission as a researcher is to contribute to improving people’s health by providing guidance to stakeholders on the implementation of public health measures. She concentrates on highly relevant emerging and established infectious diseases that require massive control efforts and have a large societal impact. Dr. Rozhnova is interested in understanding the emergence, evolution, and spatio-temporal dynamics of infectious diseases on various scales (e.g., host, hospital/school, or population) and evaluating the impact of interventions on disease transmission. Her most recent research aims to explore the prospects of HIV elimination, promising HIV cure strategies, and the (post-)pandemic dynamics of SARS-CoV-2. Other applications include influenza, CMV, and childhood infections. 

Dr Rozhnova is a recipient of highly competitive awards (PhD and postdoctoral fellowships from the Portuguese Foundation for Science and Technology, Award "Stimulus for Research" from Calouste Gulbenkian Foundation), institutional excellence programs (Research Career Development Program) and grants (list below). She held official appointments as an invited visiting scientist at the University of California (Santa Barbara, USA), the Newton Institute for Mathematical Sciences (Cambridge, UK), the Gladstone Institute of Immunology and Virology (San Francisco, USA), and the MRC Biostatistics Unit (Cambridge, UK). The main funders of her current research are Aidsfonds, FCT, NWO, ZonMw and European Commission. 

Selected recent scientific publications:

  • Boldea O, Alipoor A, Pei S, Shaman J, Rozhnova G. Age-specific transmission dynamics of SARS-CoV-2 during the first 2 years of the pandemic. PNAS Nexus 3(2), pgae024 (2024). https://doi.org/10.1093/pnasnexus/pgae024 [OA]
  • Rouzine IM, Rozhnova G. Evolutionary implications of SARS-CoV-2 vaccination for the future design of vaccination strategies. Communications Medicine 3(1), 86 (2023). https://doi.org/10.1038/s43856-023-00320-x [OA]
  • Romijnders K, de Groot L, Vervoort S, Basten M, van Welzen B, Kretzschmar M, Reiss P, Davidovich U, Rozhnova G. The perceived impact of an HIV cure by people living with HIV and key populations vulnerable to HIV in the Netherlands: A qualitative study. Journal of Virus Eradication 8(1), 100066 (2022). https://doi.org/10.1016/j.jve.2022.100066 [OA]
  • Viana J, van Dorp CH, Nunes A, Gomes MC, van Boven M, Kretzschmar ME, Veldhoen M, Rozhnova G. Controlling the pandemic during the SARS-CoV-2 vaccination rollout. Nature Communications 12, 3674 (2021). https://doi.org/10.1038/s41467-021-23938-8 [OA]
  • Rozhnova G, van Dorp CH, Bruijning-Verhagen P, Bootsma MCJ, van de Wijgert JHHM, Bonten MJM, Kretzschmar ME. Model-based evaluation of school- and non-school-related measures to control the COVID-19 pandemic. Nature Communications 12, 1614 (2021). https://doi.org/10.1038/s41467-021-21899-6 [OA]
  • Teslya A, Pham TM, Godijk NG, Kretzschmar ME, Bootsma MCJ, Rozhnova G. Impact of self-imposed prevention measures and short-term government-imposed social distancing on mitigating and delaying a COVID-19 epidemic: A modelling study. PLoS Medicine 17(7), e1003166 (2020). https://doi.org/10.1371/journal.pmed.1003166 [OA]
  • Rouzine IM, Rozhnova G. Antigenic evolution of viruses in host populations. PLoS Pathogens 14(9), e1007291 (2018). https://doi.org/10.1371/journal.ppat.1007291 [OA]

Side Activities

  • Editorial Board Member, Communications Medicine, Nature Portfolio
  • Editorial Board Member, Mathematical Biosciences, Epidemiology and Public Health specialty section, Elsevier
  • Editorial Board Member, Frontiers in Epidemiology, Infectious Disease Epidemiology specialty section
  • Chair, Young Academy, University Medical Center Utrecht
  • Associate Member, Centre for Complex Systems Studies, Utrecht University
  • Member, European Women in Mathematics
  • Member, Institute of Physics
  • Member, Society for Industrial and Applied Mathematics

Fellowship and Awards

  • ZonMw grant (2023-2024). Role: Principal Investigator. €235k. Contract No. 10430362220002. "CoviChron: Covid-19 and Chronic illness interactions in transmission dynamics".
  • ZonMw-NCOH grant (2023-2025). Role: Task Lead in WP4 Risk Prediction Models. €2.5M (total), €450k (University Medical Center Utrecht). Contract No. 10710022210003. "NCOH Pandemic Preparedness Research Kickstarter".
  • Horizon Europe project (2022-2025). Role: Co-Applicant/University Medical Center Utrecht partner, co-chair Working Group on Transmission across all WPs, Task Lead in WP4 Model. €5M (total), €470k (University Medical Center Utrecht). Grant Agreement No. 10104598. VERDI Monkeypox Amendment.
  • Portuguese Foundation for Science and Technology grant (2023-2025). Role: Principal Investigator. €250k. Contract No. 2022.01448.PTDC. "Targeted control of COVID-19 post mass vaccination".
  • NORDITA Program (2023). Role: Principal Investigator, organizer. €44k. "Unifying the epidemiological and evolutionary dynamics of pathogens".
  • Horizon Europe project (2021-2025). Roles: Co-Applicant/University Medical Center Utrecht partner, co-chair Working Group on Transmission across all WPs, Task Lead in WP4 Model. €10M (total), €671k (University Medical Center Utrecht). Grant Agreement No. 10104598. "VERDI: SARS-coV2 variants Evaluation in pRegnancy and paeDIatrics cohorts".
  • Selected for Research Career Development Program for Assistant Professors, University Medical Center Utrecht (2021).
  • Aidsfonds grant (2020-2024). Role: Principal Investigator. €275k. Contract No. P-53902. "Prospects of HIV elimination among Dutch MSM by targeted screening for acute HIV infection and partner notification".
  • Aidsfonds grant (2020-2023). Role: Principal Investigator. €275k. Contract No. P-52901. "Making HIV cure work: impact on quality of life, risk behavior, and the Dutch epidemic".
  • RESEARCH 4 COVID-19 grant from the Portuguese Foundation for Science and Technology (2020). Role: Principal Investigator. €17,5k. Contract No. 131_596787873. "Making the way out: model-based evaluation of exit strategies from the COVID-19 lockdown in Portugal".
  • ZonMw grant (2019-2021). Role: Co-Applicant. €47k. Contract No. 522008010. "Gini in a bottle: Impact of PrEP on sexual behavior and sexually transmitted infections in the MSM population".
  • ZonMw grant (2018-2020). Role: Co-Applicant. €170k. Contract No. 522004009. "Risk underestimation, high-risk sexual behavior episodes and estimating the impact of tailored interventions".
  • Invited visiting scientist, MRC Biostatistics Unit, Cambridge, UK (2016-2017).
  • Invited visiting scientist, Cologne University, Cologne, Germany (2011–2014). Position funded by SFB 680, Molecular Basis of Evolutionary Innovations. 
  • Invited visiting scientist, Gladstone Institute of Immunology and Virology, San Francisco, CA, USA (2013).
  • Invited visiting scientist, Isaac Newton Institute for Mathematical Sciences, Cambridge, UK (2013). Program "Infectious Disease Dynamics".
  • CALSIMLAB scholarship from the Institut du Calcul et de la Simulation, Paris, France (2013).
  • CoSyDy grant from the Warwick University, Warwick, UK (2012).
  • Invited visiting scientist, University of California, Santa Barbara, CA, USA (2011). KITP Program "Microbial and Viral Evolution".
  • Postdoctoral Fellowship from the Portuguese Foundation for Science and Technology (2010-2013). Role: Principal Investigator. €90k. Contract No. SFRH/BPD/69137/2010. "Stochastic metapopulation models for infection dynamics and viral evolution".
  • Award "Stimulus for research" from the Calouste Gulbenkian Foundation (2007-2010). Role: Principal Investigator. €12,5k. "The physics of populations: the role of the contact network in the competition of species and in the propagation of diseases".
  • PhD Fellowship from the Portuguese Foundation for Science and Technology (2006-2010). Role: Principal Investigator. €60k. Contract No. SFRH/BD/32164/2006. "Spatio-temporal patterns on complex networks: the role of the structure of the interaction network".
  • Merit Scholarship from V. N. Karazin Kharkiv National University, Kharkiv, Ukraine (2000-2004).
  • Gold Medal "For a Marked Progress in Studies" from the Ministry of Education of Ukraine (2000).

Research Output (40)

The impact of variant and vaccination on SARS-CoV-2 symptomatology; three prospective household cohorts

Westerhof Ilse, de Hoog Marieke, Ieven Margareta, Lammens Christine, van Beek Janko, Rozhnova Ganna, Eggink Dirk, Euser Sjoerd, Wildenbeest Joanne, Duijts Liesbeth, van Houten Marlies, Goossens Herman, Giaquinto Carlo, Bruijning-Verhagen Patricia Mar 2023, In: International Journal of Infectious Diseases. 128 , p. 140-147 8 p.

The experienced positive and negative influence of HIV on quality of life of people with HIV and vulnerable to HIV in the Netherlands

Romijnders Kim A.G.J., de Groot Laura, Vervoort Sigrid C.J.M., Basten Maartje, van Welzen Berend J., Kretzschmar Mirjam E., Reiss Peter, Davidovich Udi, van der Loeff Maarten F.Schim, Rozhnova Ganna 19 Dec 2022, In: Scientific Reports. 12

The importance of sustained compliance with physical distancing during COVID-19 vaccination rollout

Teslya Alexandra, Rozhnova Ganna, Pham Thi Mui, van Wees Daphne A, Nunner Hendrik, Godijk Noortje G, Bootsma Martin, Kretzschmar Mirjam E 19 Nov 2022, In: Communications medicine. 2

Challenges for modelling interventions for future pandemics

Kretzschmar Mirjam E., Ashby Ben, Fearon Elizabeth, Overton Christopher E., Panovska-Griffiths Jasmina, Pellis Lorenzo, Quaife Matthew, Rozhnova Ganna, Scarabel Francesca, Stage Helena B., Swallow Ben, Thompson Robin N., Tildesley Michael J., Villela Daniel Mar 2022, In: Epidemics. 38

The perceived impact of an HIV cure by people living with HIV and key populations vulnerable to HIV in the Netherlands:A qualitative study

Romijnders Kim A.G.J., de Groot Laura, Vervoort Sigrid C.J.M., Basten Maartje G.J., van Welzen Berend J., Kretzschmar Mirjam E., Reiss Peter, Davidovich Udi, Rozhnova Ganna Mar 2022, In: Journal of virus eradication. 8 , p. 1-7

Time for change: transitions between HIV risk levels and determinants of behavior change in men who have sex with men

Basten Maartje G J, van Wees Daphne A, Matser Amy, Boyd Anders, Rozhnova Ganna, den Daas Chantal, Kretzschmar Mirjam E E, Heijne Janneke C M Dec 2021, In: PLoS ONE. 16 , p. 1-13

Quantifying heterogeneity in sexual behaviour and distribution of STIs before and after pre-exposure prophylaxis among men who have sex with men

van Wees Daphne Amanda, Diexer Sophie, Rozhnova Ganna, Matser Amy, den Daas Chantal, Heijne Janneke, Kretzschmar Mirjam 28 Oct 2021, In: Sexually Transmitted Infections. 98 , p. 395-400 6 p.

Derde rapport modellering SARS-CoV-2 infecties in het voortgezet onderwijs

Pham Thi Mui, Westerhof Ilse, Rozhnova Ganna, Bootsma Martin, Kretzschmar Mirjam, Bruijning-Verhagen P. 7 Sep 2021, 32 p.

Modelling the impact of preventive measures on the transmission of SARS-CoV-2 in secondary schools in the Netherlands

Pham Thi Mui, Rozhnova Ganna, Westerhof Ilse, Bootsma Martin, Kretzschmar Mirjam, Bruijning-Verhagen P. 13 Aug 2021,

Tweede rapport modellering SARS-CoV-2 infecties in het voortgezet onderwijs

Pham Thi Mui, Westerhof Ilse, Rozhnova Ganna, Bootsma Martin, Kretzschmar Mirjam, Bruijning-Verhagen P. 7 Jul 2021, 28 p.

All research output

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