Associate Professor P.M. van Hasselt
Associate Professor - medical
- Cluster C
- Metabolic diseases patient care
Contact
Biography
2019-present Associate Professor (Universitair hoofddocent (UHD))
2018-present Head of subspecialty Metabolic diseases (from August 2018)
2017-present Head of Cluster C (subspecialties Endocrinology, Metabolic diseases, MDL, Nephrology) at WKZ
2015-present 'Opleider' at department of Metabolic Diseases
2010-present Staff member at department of Metabolic Diseases
2007-present Pediatrician for Metabolic Diseases, Wilhelmina Children’s Hospital, Utrecht.
2004-2009: PhD “Vitamin K prophylaxis revisited – focus on risk factors”. Utrecht University. Promotors: Prof.Dr. R. Berger and Prof.dr. J.J.L. Kimpen
2004-2007: Subspecialty training (fellowship) for Metabolic Diseases, Wilhelmina Children’s Hospital. Head: Dr. T.J. de Koning
1999-2004: Pediatric specialty training. Wilhelmina Children’s Hospital, Utrecht and Isala Clinics, Zwolle. Head: Prof.dr. J.J.L. Kimpen
1998-1999: Physician-researcher at Netherlands Institute of Neuroscience, Amsterdam. Head: Prof R. Buis;
1997-1998: Physician at Department of Neonatology, Wilhelmina Children’s Hospital, Utrecht
1994-1997: Artsexamen (MD), University of Groningen
1989-1994: Doctoral Medicine (MSc), University of Groningen
1988-1989: Freshman-year at Wittenburg University, Springfield OH, USA (supported by scholarship through NACEE, now known as Fulbright Center)
Research Output (130)
Untargeted metabolomics for metabolic diagnostic screening with automated data interpretation using a knowledge-based algorithm
Haijes Hanneke A., van der Ham Maria, Prinsen Hubertus C.M.T., Broeks Melissa H., van Hasselt Peter M., de Sain-Van der Velden Monique G.M., Verhoeven-Duif Nanda M., Jans Judith J.M. 1 feb 2020, In: International journal of molecular sciences. 21 12 p.
Metachromatic leukodystrophy and transplantation:remyelination, no cross-correction
Wolf Nicole I., Breur Marjolein, Plug Bonnie, Beerepoot Shanice, Westerveld Aimee S.R., van Rappard Diane F., de Vries Sharon I., Kole Maarten H.P., Vanderver Adeline, van der Knaap Marjo S., Lindemans Caroline A., van Hasselt Peter M., Boelens Jaap J., Matzner Ulrich, Gieselmann Volkmar, Bugiani Marianna 22 jan 2020, In: Annals of Clinical and Translational Neurology. 7 , p. 169-180 12 p.
Synapse alterations precede neuronal damage and storage pathology in a human cerebral organoid model of CLN3-juvenile neuronal ceroid lipofuscinosis
Gomez-Giro Gemma, Arias-Fuenzalida Jonathan, Jarazo Javier, Zeuschner Dagmar, Ali Muhammad, Possemis Nina, Bolognin Silvia, Halder Rashi, Jäger Christian, Kuper Willemijn F.E., Van Hasselt Peter M., Zaehres Holm, Del Sol Antonio, Van Der Putten Herman, Schöler Hans R., Schwamborn Jens C. 30 dec 2019, In: Acta neuropathologica communications. 7
Emotional and behavioral problems, quality of life and metabolic control in NTBC-treated Tyrosinemia type 1 patients
van Vliet Kimber, van Ginkel Willem G., Jahja Rianne, Daly Anne, MacDonald Anita, De Laet Corinne, Vara Roshni, Rahman Yusof, Cassiman David, Eyskens Francois, Timmer Corrie, Mumford Nicky, Bierau Jörgen, van Hasselt Peter M., Gissen Paul, Goyens Philippe J., McKiernan Patrick J., Wilcox Gisela, Morris Andrew A.M., Jameson Elisabeth A., Huijbregts Stephan C.J., van Spronsen Francjan J. 4 dec 2019, In: Orphanet Journal of Rare Diseases. 14 9 p.
Disruptive variants of CSDE1 associate with autism and interfere with neuronal development and synaptic transmission
Guo Hui, Li Ying, Shen Lu, Wang Tianyun, Jia Xiangbin, Liu Lijuan, Xu Tao, Ou Mengzhu, Hoekzema Kendra, Wu Huidan, Gillentine Madelyn A., Liu Cenying, Ni Hailun, Peng Pengwei, Zhao Rongjuan, Zhang Yu, Phornphutkul Chanika, Stegmann Alexander P.A., Prada Carlos E., Hopkin Robert J., Shieh Joseph T., McWalter Kirsty, Monaghan Kristin G., van Hasselt Peter M., van Gassen Koen, Bai Ting, Long Min, Han Lin, Quan Yingting, Chen Meilin, Zhang Yaowen, Li Kuokuo, Zhang Qiumeng, Tan Jieqiong, Zhu Tengfei, Liu Yaning, Pang Nan, Peng Jing, Scott Daryl A., Lalani Seema R., Azamian Mahshid, Mancini Grazia M.S., Adams Darius J., Kvarnung Malin, Lindstrand Anna, Nordgren Ann, Pevsner Jonathan, Osei-Owusu Ikeoluwa A., Romano Corrado, Calabrese Giuseppe 25 sep 2019, In: Science advances. 5
Glutaminase deficiency caused by short tandem repeat expansion in GLS
Rumping Lynne, Jans Judith J., Van Hasselt Peter M. 19 sep 2019, In: New England Journal of Medicine. 381 , p. 1185-1185 1 p.
Biallelic Variants in ASNA1, Encoding a Cytosolic Targeting Factor of Tail-Anchored Proteins, Cause Rapidly Progressive Pediatric Cardiomyopathy
Verhagen Judith M.A., van den Born Myrthe, van der Linde Herma C., G J Nikkels Peter, Verdijk Rob M., Kivlen Maryann H., van Unen Leontine M.A., Baas Annette F., Ter Heide Henriette, van Osch-Gevers Lennie, Hoogeveen-Westerveld Marianne, Herkert Johanna C., Bertoli-Avella Aida M., van Slegtenhorst Marjon A., Wessels Marja W., Verheijen Frans W., Hassel David, Hofstra Robert M.W., Hegde Ramanujan S., van Hasselt Peter M., van Ham Tjakko J., van de Laar Ingrid M.B.H. 1 sep 2019, In: Circulation. Genomic and precision medicine. 12 , p. 397-406 10 p.
Pathophysiology of propionic and methylmalonic acidemias. Part 1:Complications
Haijes Hanneke A., Jans Judith J.M., Tas Simone Y., Verhoeven-Duif Nanda M., van Hasselt Peter M. sep 2019, In: Journal of Inherited Metabolic Disease. 42 , p. 730-744 15 p.
Pathophysiology of propionic and methylmalonic acidemias. Part 2:Treatment strategies
Haijes Hanneke A., van Hasselt Peter M., Jans Judith J.M., Verhoeven-Duif Nanda M. sep 2019, In: Journal of Inherited Metabolic Disease. 42 , p. 745-761 17 p.
De Novo Heterozygous POLR2A Variants Cause a Neurodevelopmental Syndrome with Profound Infantile-Onset Hypotonia
Haijes Hanneke A., Koster Maria J.E., Rehmann Holger, Li Dong, Hakonarson H., Cappuccio Gerarda, Hancarova Miroslava, Lehalle Daphne, Reardon Willie, Schaefer G. Bradley, Lehman Anna, van de Laar Ingrid M.B.H., Tesselaar Coranne D., Turner Clesson, Goldenberg A., Patrier Sophie, Thevenon Julien, Pinelli Michele, Brunetti-Pierri Nicola, Prchalová Darina, Havlovicová Markéta, Vlckova Markéta, Sedláček Zdeněk, Lopez E., Ragoussis Vassilis, Pagnamenta Alistair T., Kini Usha, Vos Harmjan R., van Es Robert M., van Schaik Richard F.M.A., van Essen Ton A.J., Kibaek M., Taylor Jenny C., Sullivan Jennifer, Shashi Vandana, Petrovski S., Fagerberg Christina, Martin Donna M., van Gassen Koen L.I., Pfundt R., Falk Marni J., McCormick Elizabeth M., Timmers H. T.Marc, van Hasselt Peter M. 1 aug 2019, In: American Journal of Human Genetics. 105 , p. 283-301 19 p.