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Associate Professor P.M. van Hasselt

Associate Professor - medical
Associate Professor P.M. van Hasselt
  • Metabolic diseases patient care

Biography

Biography

2020-present       Research Manager WKZ

2019-present       Associate Professor (Universitair hoofddocent UHD)

2017-present       Head of subspecialty Metabolic diseases (from August 2018)

2017-2020          Head of Cluster C (subspecialties Endocrinology, Metabolic diseases, MDL, Nephrology) at WKZ  

2015-present       'Opleider' at department of Metabolic Diseases     

2009-present       Staff member at department of Metabolic Diseases

2007-present       Pediatrician for Metabolic Diseases, Wilhelmina Children’s Hospital, Utrecht.

2004-2009           PhD “Vitamin K prophylaxis revisited – focus on risk factors”. Utrecht University. Promotors: Prof.Dr. R. Berger and Prof.dr. J.J.L. Kimpen

2004-2007           Subspecialty training (fellowship) for Metabolic Diseases, Wilhelmina Children’s Hospital. Head: Dr. T.J. de Koning

1999-2004           Pediatric specialty training. Wilhelmina Children’s Hospital, Utrecht and Isala Clinics, Zwolle. Head: Prof.dr. J.J.L. Kimpen

1998-1999           Physician-researcher at Netherlands Institute of Neuroscience, Amsterdam. Head: Prof R. Buis;

1997-1998           Physician at Department of Neonatology, Wilhelmina Children’s Hospital, Utrecht

1994-1997           Artsexamen (MD), University of Groningen

1989-1994           Doctoral Medicine (MSc), University of Groningen

1988-1989           Freshman-year at Wittenburg University, Springfield OH, USA (supported by scholarship through NACEE, now known as Fulbright Center)

Research Output (146)

Prime editing for functional repair in patient-derived disease models

Schene Imre F, Joore Indi P, Oka Rurika, Mokry Michal, van Vugt Anke H M, van Boxtel Ruben, van der Doef Hubert P J, van der Laan Luc J W, Verstegen Monique M A, van Hasselt Peter M, Nieuwenhuis Edward E S, Fuchs Sabine A 1 dec 2020, In: Nature Communications. 11

Quantifying lymphocyte vacuolization serves as a measure of CLN3 disease severity

Kuper Willemijn F E, Oostendorp Marlies, van den Broek Brigitte T A, van Veghel Karin, Nonkes Lourens J P, Nieuwenhuis Edward E S, Fuchs Sabine A, Veenendaal Tineke, Klumperman Judith, Huisman Albert, Nierkens Stefan, van Hasselt Peter M jul 2020, In: JIMD Reports. 54 , p. 87-97 11 p.

HEARING LOSS IN PATIENTS WITH MUCOPOLYSACCHARIDOSES-1 AND -6 AFTER HEMATOPOIETIC CELL TRANSPLANTATION; a longitudinal analysis

van den Broek Brigitte T A, Smit Adriana L, Boelens Jaap Jan, van Hasselt Peter M 24 jun 2020, In: Journal of Inherited Metabolic Disease. 43 , p. 1279-1287 9 p.

Hurdles in treating Hurler disease:potential routes to achieve a "real" cure

van den Broek Brigitte T A, van Doorn Jaap, Hegeman Charlotte V, Nierkens Stefan, Lindemans Caroline A, Verhoeven-Duif Nanda, Boelens Jaap Jan, van Hasselt Peter M 23 jun 2020, In: Blood Advances. 4 , p. 2837-2849 13 p.

Cross-omics:Integrating genomics with metabolomics in clinical diagnostics

Kerkhofs Marten H.P.M., Haijes Hanneke A., Marcel Willemsen A., Van Gassen Koen L.I., Van Der Ham Maria, Gerrits Johan, De Sain-Van Der Velden Monique G.M., Prinsen Hubertus C.M.T., Van Deutekom Hanneke W.M., Van Hasselt Peter M., Verhoeven-Duif Nanda M., Jans Judith J.M. 18 mei 2020, In: Metabolites. 10 15 p.

Understanding acute metabolic decompensation in propionic and methylmalonic acidemias:a deep metabolic phenotyping approach

Haijes H A, Jans J J M, van der Ham M, van Hasselt P M, Verhoeven-Duif N M 6 mrt 2020, In: Orphanet Journal of Rare Diseases. 15 , p. 1-13

Metabolic fingerprinting reveals extensive consequences of GLS hyperactivity

Rumping Lynne, Pras-Raves Mia L, Gerrits Johan, Tang Yuen Fung, Willemsen Marcel A, Houwen Roderick H J, van Haaften Gijs, van Hasselt Peter M, Verhoeven-Duif Nanda M, Jans Judith J M 1 mrt 2020, In: Biochimica et biophysica acta-General subjects. 1864 , p. 1-7

Accurate discrimination of Hartnup disorder from other aminoacidurias using a diagnostic ratio

Haijes H. A., Prinsen Hubertus C.M.T., de Sain-van der Velden Monique G.M., Verhoeven-Duif Nanda M., van Hasselt Peter M., Jans Judith J.M. mrt 2020, In: Molecular Genetics and Metabolism Reports. 22 , p. 1-6

The c.1A > C start codon mutation in CLN3 is associated with a protracted disease course

Kuper Willemijn F E, van Alfen Claudia, van Eck Linda, de Man Stella A, Willemsen Marjolein H, van Gassen Koen L I, Losekoot Monique, van Hasselt Peter M mrt 2020, In: JIMD Reports. 52 , p. 23-27 5 p.

Untargeted metabolomics for metabolic diagnostic screening with automated data interpretation using a knowledge-based algorithm

Haijes Hanneke A., van der Ham Maria, Prinsen Hubertus C.M.T., Broeks Melissa H., van Hasselt Peter M., de Sain-Van der Velden Monique G.M., Verhoeven-Duif Nanda M., Jans Judith J.M. 1 feb 2020, In: International journal of molecular sciences. 21 12 p.

All research output