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dr. H.A. (Richard) van Wijk

dr. H.A. (Richard) van Wijk

Associate Professor

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Research Output (129)

AG-348 (Mitapivat), an allosteric activator of red blood cell pyruvate kinase, increases enzymatic activity, protein stability, and ATP levels over a broad range of PKLR genotypes

Rab Minke A E, van Oirschot Brigitte A, Kosinski Penelope A, Hixon Jeffrey, Johnson Kendall, Chubukov Victor, Dang Lenny, Pasterkamp Gerard, van Straaten Stephanie, van Solinge Wouter W, van Beers Eduard J, Kung Charles, van Wijk Richard 23 Jan 2020, In: Haematologica. 106 , p. 238-249 12 p.

Methodological aspects of the oxygenscan in sickle cell disease:A need for standardization

Rab MAE, Kanne Celeste K., Bos Jennifer, Boisson Camille, van Oirschot Brigitte A., Nader Elie, Renoux Céline, Joly Philippe, Fort Romain, van Beers Eduard J., Sheehan Vivien A., van Wijk Richard, Connes Philippe Jan 2020, In: American Journal of Hematology. 95 , p. E5-E8

Chapter 48: Erythrocyte Enzyme Disorders

Bartels M, van Beers Eduard, van Wijk Richard 2020, p. 749-784 35 p.

Characterization of Sickling During Controlled Automated Deoxygenation with Oxygen Gradient Ektacytometry

Rab Minke A E, van Oirschot Brigitte A, Bos Jennifer, Kanne Celeste K, Sheehan Vivien A, van Beers Eduard J, van Wijk Richard 5 Nov 2019, In: Journal of visualized experiments : JoVE. 2019

The Complexity of Genotype-Phenotype Correlations in Hereditary Spherocytosis:A Cohort of 95 Patients: Genotype-Phenotype Correlation in Hereditary Spherocytosis

van Vuren Annelies, van der Zwaag Bert, Huisjes Rick, Lak Nathalie, Bierings Marc, Gerritsen Egbert, van Beers Eduard, Bartels Marije, van Wijk Richard Aug 2019, In: HemaSphere. 3

Red Blood Cells:Chasing Interactions

Pretini Virginia, Koenen Mischa H, Kaestner Lars, Fens Marcel H A M, Schiffelers Raymond M, Bartels Marije, Van Wijk Richard 31 Jul 2019, In: Frontiers in Physiology. 10

The EPO-FGF23 Signaling Pathway in Erythroid Progenitor Cells:Opening a New Area of Research

Van Vuren Annelies J., Gaillard Carlo A.J.M., Eisenga Michele F., Van Wijk Richard, Van Beers Eduard J. 26 Mar 2019, In: Frontiers in Physiology. 10

Rapid and reproducible characterization of sickling during automated deoxygenation in sickle cell disease patients

Rab Minke A.E., van Oirschot Brigitte A., Bos Jennifer, Merkx Tesy H., van Wesel Annet C.W., Abdulmalik Osheiza, Safo Martin K., Versluijs Birgitta A., Houwing Maite E., Cnossen Marjon H., Riedl Jurgen, Schutgens Roger E.G., Pasterkamp Gerard, Bartels Marije, van Beers Eduard J., van Wijk Richard 19 Feb 2019, In: American Journal of Hematology. 94 , p. 575-584 10 p.

Addressing the diagnostic gaps in pyruvate kinase deficiency:Consensus recommendations on the diagnosis of pyruvate kinase deficiency

Bianchi Paola, Fermo Elisa, Glader Bertil, Kanno Hitoshi, Agarwal Archana, Barcellini Wilma, Eber Stefan, Hoyer James D., Kuter David J., Maia Tabita Magalhães, Mañu-Pereira Maria del Mar, Kalfa Theodosia A., Pissard Serge, Segovia José Carlos, van Beers Eduard, Gallagher Patrick G., Rees David C., van Wijk Richard, 1 Jan 2019, In: American Journal of Hematology. 94 , p. 149-161 13 p.

Density, heterogeneity and deformability of red cells as markers of clinical severity in hereditary spherocytosis

Huisjes Rick, Mahkro A, Llaudet-Planas Esther, Hertz L, Petkova-Kirova P, Verhagen LP, Pignatelli Silvia, Rab MAE, Schiffelers Raymond, Seiler E, van Solinge W.W., Vives-Corrons J.-L., Mañu-Pereira Maria del Mar, Kaestner Lars, Bogdanova Anna, van Wijk Richard 2019, In: Haematologica. 105 , p. 338-347 10 p.

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