dr. S.M. (Stefan) Willems

Associate Professor - medical
  • Department of Pathology

Research Programs

Strategic Program Cancer



Dr Stefan Willems was trained in medicin (2003 cum laude Catholic University Leuven) with a PhD in molecular pathology (2010, Leiden University) and specialized in pathology (2011, LUMC). After postdoc positions at Harvard Medical School (Gygilab) and NKI  (Bernardslab) he has been working as a pathologist with special interest in molecular pathology and diagnostics. He is co-director of the molecular pathology lab in the University Medical Center Utrecht. He is associate professor in pathology and head of the molecular head and neck cancer line within the UMC Utrecht (1 postdoc, 8 PhDs). He is also affiliated with the department of pathology of the NKI-AvL and performs here translational head and neck research. He is board member of the PALGA Foundation.

Research Output (158)

Presence of Human Papillomavirus and Epstein-Barr Virus, but Absence of Merkel Cell Polyomavirus, in Head and Neck Cancer of Non-Smokers and Non-Drinkers

Mulder Frans J, Klufah Faisal, Janssen Famke M E, Farshadpour Farzaneh, Willems Stefan M, de Bree Remco, Zur Hausen Axel, van den Hout Mari F C M, Kremer Bernd, Speel Ernst-Jan M 2021, In: Frontiers in oncology. 10 , p. 560434

Assessment of tumour depth in early tongue cancer:Accuracy of MRI and intraoral ultrasound

Noorlag Rob, Klein Nulent Thomas J W, Delwel Valerie E J, Pameijer Frank A, Willems Stefan M, de Bree Remco, van Es Robert J J 9 jul 2020, In: Oral Oncology. 110 , p. 1-5

Elective Neck Dissection or Sentinel Lymph Node Biopsy in Early Stage Oral Cavity Cancer Patients:The Dutch Experience

den Toom Inne J, Boeve Koos, Lobeek Daphne, Bloemena Elisabeth, Donswijk Maarten L, de Keizer Bart, Klop W Martin C, Leemans C René, Willems Stefan M, Takes Robert P, Witjes Max J H, de Bree Remco 3 jul 2020, In: Cancers. 12 12 p.

Prostate-specific membrane antigen (PSMA) expression in adenoid cystic carcinoma of the head and neck

Klein Nulent Thomas J W, Valstar Matthijs H, Smit Laura A, Smeele Ludwig E, Zuithoff Nicolaas P A, de Keizer Bart, de Bree Remco, van Es Robert J J, Willems Stefan M 5 jun 2020, In: BMC Cancer. 20 9 p.

Digital pathology-aided assessment of tumor-infiltrating T lymphocytes in advanced stage, HPV-negative head and neck tumors

de Ruiter Emma J, de Roest Reinout H, Brakenhoff Ruud H, Leemans C René, de Bree Remco, Terhaard Chris H J, Willems Stefan M 24 jan 2020, In: Cancer Immunology, Immunotherapy. 69 , p. 581-591 11 p.

High CXCR4 expression in adenoid cystic carcinoma of the head and neck is associated with increased risk of locoregional recurrence

Klein Nulent Thomas J W, van Es Robert J J, Valstar Matthijs H, Smeele Ludwig E, Smit Laura A, Klein Gunnewiek Raquel, Zuithoff Nicolaas P A, de Keizer Bart, de Bree Remco, Willems Stefan 16 jan 2020, In: Journal of Clinical Pathology. 73 , p. 476-482 7 p.

The prognostic role of NK cells and their ligands in squamous cell carcinoma of the head and neck:a systematic review and meta-analysis

Bisheshar Sangeeta K., De Ruiter Emma J., Devriese Lot A., Willems Stefan M. 1 jan 2020, In: OncoImmunology. 9 10 p.

HIF-1a expression and differential effects on survival in patients with oral cavity, larynx, and oropharynx squamous cell carcinomas

Swartz Justin E, Wegner Inge, Noorlag Rob, van Kempen Pauline M W, van Es Robert J J, de Bree Remco, Willems Stefan M W 2020, In: Head & neck. 43 , p. 745-756 12 p.

MET ectodomain shedding is associated with poor disease-free survival of patients diagnosed with oral squamous cell carcinoma

De Herdt Maria J, Koljenović Senada, van der Steen Berdine, Willems Stefan M, Noorlag Rob, Nieboer Daan, Hardillo Jose A, Gruver Aaron M, Zeng Wei, Liu Ling, de Jong Robert J Baatenburg, Looijenga Leendert H 19 dec 2019, In: Modern Pathology. 33 , p. 1015-1032 18 p.

Inflammatory pseudotumour of the alveolar process of the maxilla as clinical manifestation of IgG4-related disease:a case report and literature review

Kouwenberg W L, Dieleman F J, Willems S M, Rosenberg A J W P 18 dec 2019, In: International Journal of Oral and Maxillofacial Surgery. 49 , p. 722-725 4 p.

All research output

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