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dr. S.M. (Stefan) Willems

dr. S.M. (Stefan) Willems

Associate Professor - medical
  • Department of Pathology

Research Programs

Strategic Program Cancer

Biography

Biography

Dr Stefan Willems was trained in medicin (2003 cum laude Catholic University Leuven) with a PhD in molecular pathology (2010, Leiden University) and specialized in pathology (2011, LUMC). After postdoc positions at Harvard Medical School (Gygilab) and NKI  (Bernardslab) he has been working as a pathologist with special interest in molecular pathology and diagnostics. He is co-director of the molecular pathology lab in the University Medical Center Utrecht. He is associate professor in pathology and head of the molecular head and neck cancer line within the UMC Utrecht (1 postdoc, 8 PhDs). He is also affiliated with the department of pathology of the NKI-AvL and performs here translational head and neck research. He is board member of the PALGA Foundation.

Research Output (176)

Association of histological features with laryngeal squamous cell carcinoma recurrences:a population-based study of 1502 patients in the Netherlands

Ruiter Lilian N, van Dijk Boukje A C, Bruggink Annette H, Doornaert Patricia A H, Philippens Marielle E P, de Bree Remco, van Gils Carla H, Willems Stefan M Dec 2022, In: BMC Cancer. 22 , p. 1-10

Assessing the prognostic value of tumor-infiltrating CD57+ cells in advanced stage head and neck cancer using QuPath digital image analysis

de Ruiter Emma J, Bisheshar Sangeeta K, de Roest Reinout H, Wesseling Frederik W R, Hoebers Frank J P, van den Hout Mari F C M, Leemans C René, Brakenhoff Ruud H, de Bree Remco, Terhaard Chris H J, Willems Stefan M 22 Apr 2022, In: Virchows Archives. 481 , p. 223-231 9 p.

Correlation and colocalization of HIF-1α and pimonidazole staining for hypoxia in laryngeal squamous cell carcinomas:A digital, single-cell-based analysis

Swartz Justin E, Smits Hilde J G, Philippens Marielle E P, de Bree Remco, H A M Kaanders Johannes, Willems Stefan M 18 Apr 2022, In: Oral Oncology. 128 , p. 1-8

Prognostic Value of Stromal Tumor-Infiltrating Lymphocytes in Young, Node-Negative, Triple-Negative Breast Cancer Patients Who Did Not Receive (neo)Adjuvant Systemic Therapy

de Jong Vincent M T, Wang Yuwei, Ter Hoeve Natalie D, Opdam Mark, Stathonikos Nikolas, Jóźwiak Katarzyna, Hauptmann Michael, Cornelissen Sten, Vreuls Willem, Rosenberg Efraim H, Koop Esther A, Varga Zsuzsanna, van Deurzen Carolien H M, Mooyaart Antien L, Córdoba Alicia, Groen Emma J, Bart Joost, Willems Stefan M, Zolota Vasiliki, Wesseling Jelle, Sapino Anna, Chmielik Ewa, Ryska Ales, Broeks Annegien, Voogd Adri C, Loi Sherene, Michiels Stefan, Sonke Gabe S, van der Wall Elsken, Siesling Sabine, van Diest Paul J, Schmidt Marjanka K, Kok Marleen, Dackus Gwen M H E, Salgado Roberto, Linn Sabine C 30 Mar 2022, In: Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 40 , p. 2361-2374 14 p.

Targeting Angiogenesis in Squamous Cell Carcinoma of the Head and Neck:Opportunities in the Immunotherapy Era

Saba Nabil F, Vijayvargiya Pooja, Vermorken Jan B, Rodrigo Juan P, Willems Stefan M, Zidar Nina, de Bree Remco, Mäkitie Antti, Wolf Greg T, Argiris Athanassios, Teng Yong, Ferlito Alfio 25 Feb 2022, In: Cancers. 14

Response to "Head and neck cancer diagnoses and faster treatment initiation during COVID-19 Correspondence"

Schoonbeek Rosanne C., de Jel Dominique V.C., van Dijk Boukje A.C., Willems Stefan M., Bloemena Elisabeth, Hoebers Frank J.P., van Meerten Esther, Verbist Berit M., Smeele Ludi E., Halmos György B., Merkx Matthias A.W., Siesling Sabine, De Bree Remco, Takes Robert P., 28 Jan 2022, In: Radiotherapy & Oncology. 169 , p. 146-147 2 p.

First experiences with 177Lu-PSMA-617 therapy for recurrent or metastatic salivary gland cancer

Klein Nulent Thomas J.W., van Es Robert J.J., Willems Stefan M., Braat Arthur J.A.T., Devriese Lot A., de Bree Remco, de Keizer Bart 14 Dec 2021, In: EJNMMI Research. 11 , p. 1-6

Accurate detection of circulating tumor DNA using nanopore consensus sequencing

Marcozzi Alessio, Jager Myrthe, Elferink Martin, Straver Roy, van Ginkel Joost H, Peltenburg Boris, Chen Li-Ting, Renkens Ivo, van Kuik Joyce, Terhaard Chris, de Bree Remco, Devriese Lot A, Willems Stefan M, Kloosterman Wigard P, de Ridder Jeroen 9 Dec 2021, In: npj Genomic Medicine. 6 , p. 1-11

De-escalation studies in HPV-positive oropharyngeal cancer:How should we proceed?

Golusinski Pawel, Corry June, Poorten Vincent Vander, Simo Ricard, Sjögren Elisabeth, Mäkitie Antti, Kowalski Luis Paulo, Langendijk Johannes, Braakhuis Boudewijn J M, Takes Robert P, Coca-Pelaz Andrés, Rodrigo Juan P, Willems Stefan M, Forastiere Arlene A, De Bree Remco, Saba Nabil F, Teng Yong, Sanabria Alvaro, Di Maio Pasquale, Szewczyk Mateusz, Ferlito Alfio 17 Nov 2021, In: Oral Oncology. 123 , p. 1-8

Considerable interlaboratory variation in PD-L1 positivity in a nationwide cohort of non-small cell lung cancer patients

Koomen Bregje M., Voorham Quirinus J.M., Epskamp-Kuijpers Chantal C.H.J., van Dooijeweert Carmen, van Lindert Anne S.R., Deckers Ivette A.G., Willems Stefan M. Sep 2021, In: Lung Cancer. 159 , p. 117-126 10 p.

All research output

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