dr. S.M. (Stefan) Willems

Associate Professor - medical
  • Department of Pathology

Research Programs

Strategic Program Cancer



Dr Stefan Willems was trained in medicin (2003 cum laude Catholic University Leuven) with a PhD in molecular pathology (2010, Leiden University) and specialized in pathology (2011, LUMC). After postdoc positions at Harvard Medical School (Gygilab) and NKI  (Bernardslab) he has been working as a pathologist with special interest in molecular pathology and diagnostics. He is co-director of the molecular pathology lab in the University Medical Center Utrecht. He is associate professor in pathology and head of the molecular head and neck cancer line within the UMC Utrecht (1 postdoc, 8 PhDs). He is also affiliated with the department of pathology of the NKI-AvL and performs here translational head and neck research. He is board member of the PALGA Foundation.

Research Output (155)

Elective Neck Dissection or Sentinel Lymph Node Biopsy in Early Stage Oral Cavity Cancer Patients:The Dutch Experience

den Toom Inne J, Boeve Koos, Lobeek Daphne, Bloemena Elisabeth, Donswijk Maarten L, de Keizer Bart, Klop W Martin C, Leemans C René, Willems Stefan M, Takes Robert P, Witjes Max J H, de Bree Remco 3 jul 2020, In: Cancers. 12 12 p.

Prostate-specific membrane antigen (PSMA) expression in adenoid cystic carcinoma of the head and neck

Klein Nulent Thomas J W, Valstar Matthijs H, Smit Laura A, Smeele Ludwig E, Zuithoff Nicolaas P A, de Keizer Bart, de Bree Remco, van Es Robert J J, Willems Stefan M 5 jun 2020, In: BMC Cancer. 20 9 p.

Digital pathology-aided assessment of tumor-infiltrating T lymphocytes in advanced stage, HPV-negative head and neck tumors

de Ruiter Emma J, de Roest Reinout H, Brakenhoff Ruud H, Leemans C René, de Bree Remco, Terhaard Chris H J, Willems Stefan M 24 jan 2020, In: Cancer Immunology, Immunotherapy. 69 , p. 581-591 11 p.

High CXCR4 expression in adenoid cystic carcinoma of the head and neck is associated with increased risk of locoregional recurrence

Klein Nulent Thomas J W, van Es Robert J J, Valstar Matthijs H, Smeele Ludwig E, Smit Laura A, Klein Gunnewiek Raquel, Zuithoff Nicolaas P A, de Keizer Bart, de Bree Remco, Willems Stefan 16 jan 2020, In: Journal of Clinical Pathology. 73 , p. 476-482 7 p.

The prognostic role of NK cells and their ligands in squamous cell carcinoma of the head and neck:a systematic review and meta-analysis

Bisheshar Sangeeta K., De Ruiter Emma J., Devriese Lot A., Willems Stefan M. 1 jan 2020, In: OncoImmunology. 9 10 p.

MET ectodomain shedding is associated with poor disease-free survival of patients diagnosed with oral squamous cell carcinoma

De Herdt Maria J, Koljenović Senada, van der Steen Berdine, Willems Stefan M, Noorlag Rob, Nieboer Daan, Hardillo Jose A, Gruver Aaron M, Zeng Wei, Liu Ling, de Jong Robert J Baatenburg, Looijenga Leendert H 19 dec 2019, In: Modern Pathology. 33 , p. 1015-1032 18 p.

Inflammatory pseudotumour of the alveolar process of the maxilla as clinical manifestation of IgG4-related disease:a case report and literature review

Kouwenberg W L, Dieleman F J, Willems S M, Rosenberg A J W P 18 dec 2019, In: International Journal of Oral and Maxillofacial Surgery. 49 , p. 722-725 4 p.

Skeletal muscle mass is an imaging biomarker for decreased survival in patients with oropharyngeal squamous cell carcinoma

Chargi N, Bril S I, Swartz J E, Wegner I, Willems S W, de Bree R 16 dec 2019, In: Oral Oncology. 101

Comparability of PD-L1 immunohistochemistry assays for non-small cell lung cancer:a systematic review

Koomen Bregje M, Badrising Sushil K, van den Heuvel Michel M, Willems Stefan M 2 dec 2019, In: Histopathology. 76 , p. 793-802 10 p.

Patient-Derived Head and Neck Cancer Organoids Recapitulate EGFR Expression Levels of Respective Tissues and Are Responsive to EGFR-Targeted Photodynamic Therapy

Driehuis Else, Spelier Sacha, Beltrán Hernández Irati, de Bree Remco, M Willems Stefan, Clevers Hans, Oliveira Sabrina 5 nov 2019, In: Journal of Clinical medicine. 8

All research output