dr. M.I. (Mirjam) Geerlings

Associate Professor

  • Department of Epidemiology
  • Julius Center Research Program Cardiovascular Epidemiology

dr. M.I. (Mirjam) Geerlings

Research Programs


I received my MSc degree in Neuropsychology and PhD degree in Epidemiology from the VU medical center Amsterdam, the Netherlands. From 2000 until 2002, I worked as a post-doc at the Department of Epidemiology & Biostatistics of the Erasmus Medical Center, Rotterdam where I studied steroid hormones as risk factors for dementia using data from the Rotterdam Study. Since 2002, I work at the Julius Center for Health Sciences and Primary Care (University Medical Center Utrecht). I initiate, conduct, and supervise research within the department of Epidemiology and develop, coordinate and teach epidemiology courses within the Biomedical Sciences (BSc), Medicine (BSc and MSc), and MSc Epidemiology curriculum. I supervised around 40 MSc and BSc students during their research and completing their MSc or BSc thesis. Additionally, I have mentored a substantial number of research assistants, PhD candidates, and postdoctoral fellows. I am a PI of the research programs Circulatory Health (research theme Cerebrovascular disease) and Brain within the UMC Utrecht. 

Within the UMC Utrecht, I lead the SMART-MR study, a sub-study of the UCC-SMART study. The SMART-MR study is an ongoing prospective cohort study among 1309 non-demented, independently living middle-aged to older adults with manifest arterial disease, aimed to investigate determinants and consequences of brain changes on MRI, including depression and cognitive decline. Individuals were assessed at up to three visits: at baseline, 4 years, and 12 years follow-up. I amalso PI of the Medea 7T study, a cohort study in the UMC Utrecht, aimed to investigate determinants and consequences of microstructural brain abnormalities on 7 tesla brain MRI. With the UCC-SMART study and SMART-MR study I participate in national and international consortia, including the Netherlands Consortium for Dementia Cohorts (NCDC), the Psychosocial factors and cancer incidence (PSY-CA) consortium, and the CHARGE consortium.

Internationally, I have longstanding collaborations with the Laboratory of Epidemiology and Population Sciences, National Institute on Aging, USA (dr. Lenore Launer) where I published using data from the Honolulu Asia Aging Study and the AGES-Reykjavik Study.


Research line

Epidemiology of cerebrovascular disease and brain health.



Research Output (205)


Zwartbol M H T, van der Kolk A G, Geerlings M I 30 apr 2020, In: AJNR. American journal of neuroradiology. 41

Microbleeds colocalize with enlarged juxtacortical perivascular spaces in amnestic mild cognitive impairment and early Alzheimer's disease:A 7 Tesla MRI study

Bouvy Willem H, van Veluw Susanne J, Kuijf Hugo J, Zwanenburg Jaco Jm, Kappelle Jaap L, Luijten Peter R, Koek Huiberdina L, Geerlings Mirjam I, Biessels Geert J, apr 2020, In: Journal of Cerebral Blood Flow and Metabolism. 40 , p. 739-746 8 p.

Intracranial Atherosclerotic Burden on 7T MRI Is Associated with Markers of Extracranial Atherosclerosis:The SMART-MR Study

Zwartbol M. H. T., Geerlings M. I., Ghaznawi R., Hendrikse J., van der Kolk A. G., Asselbergs F. W., Nathoe H. M., de Borst G. J., Bots M. L., Emmelot M. H., de Jong P. A., Leiner T., Lely A. T., van der Kaaij N. P., Kappelle L. J., Ruigrok Y. M., Verhaar M. C., Visseren F. L. J., Westerink J., 5 dec 2019, In: American Journal of Neuroradiology. 40 , p. 2016-2022 7 p.

Progress update from the hippocampal subfields group

Olsen Rosanna K, Carr Valerie A, Daugherty Ana M, La Joie Renaud, Amaral Robert S C, Amunts Katrin, Augustinack Jean C, Bakker Arnold, Bender Andrew R, Berron David, Boccardi Marina, Bocchetta Martina, Burggren Alison C, Chakravarty M Mallar, Chételat Gaël, de Flores Robin, DeKraker Jordan, Ding Song-Lin, Geerlings Mirjam I, Huang Yushan, Insausti Ricardo, Johnson Elliott G, Kanel Prabesh, Kedo Olga, Kennedy Kristen M, Keresztes Attila, Lee Joshua K, Lindenberger Ulman, Mueller Susanne G, Mulligan Elizabeth M, Ofen Noa, Palombo Daniela J, Pasquini Lorenzo, Pluta John, Raz Naftali, Rodrigue Karen M, Schlichting Margaret L, Lee Shing Yee, Stark Craig E L, Steve Trevor A, Suthana Nanthia A, Wang Lei, Werkle-Bergner Markus, Yushkevich Paul A, Yu Qijing, Wisse Laura E M, 1 dec 2019, In: Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 11 , p. 439-449 11 p.

Risk factors of mortality in older patients with dementia in psychiatric care

Goluke Nienke M S, Geerlings Mirjam I, van de Vorst Irene E, Vaartjes Ilonca H, de Jonghe Annemarieke, Bots Michiel L, Koek Huiberdina L 10 nov 2019, In: International Journal of Geriatric Psychiatry. 35 , p. 174-181 8 p.

Risk factors for in-hospital mortality in patients with dementia

Golüke Nienke M S, van de Vorst Irene E, Vaartjes Ilonca H, Geerlings Mirjam I, de Jonghe Annemarieke, Bots Michiel L, Koek Huiberdina L nov 2019, In: Maturitas. 129 , p. 57-61 5 p.

Hippocampal sulcal cavities prevalence, risk factors and association with cognitive performance. The SMART-Medea study and PREDICT-MR study

Blom Kim, Koek Huiberdina L, van der Graaf Yolanda, Zwartbol Maarten H T, Wisse Laura E M, Hendrikse Jeroen, Biessels Geert Jan, Geerlings Mirjam I, aug 2019, In: Brain Imaging and Behavior. 13 , p. 1093-1102 10 p.

Subjective cognitive decline, brain imaging biomarkers, and cognitive functioning in patients with a history of vascular disease:the SMART-Medea study

Blom Kim, Koek Huiberdina L, Zwartbol Maarten H T, van der Graaf Yolanda, Kesseler Lara, Biessels Geert Jan, Geerlings Mirjam I, 24 jul 2019, In: Neurobiology of Aging. 84 , p. 33-40 8 p.

The effect of computerized decision support systems on cardiovascular risk factors:A systematic review and meta-analysis

Groenhof T. Katrien J., Asselbergs Folkert W., Groenwold Rolf H. H., Grobbee Diederick E., Visseren Frank L. J., Bots Michiel L., Asselbergs Folkert W., Nathoe H. M., de Borst G. J., Bots Michiel L., Geerlings M. I., Emmelot M. H., de Jong P. A., Leiner T., Lely A. T., van der Kaaij N. P., Kappelle L. J., Ruigrok Y. M., Verhaar M. C., Visseren Frank L. J., Westerink J. 10 jun 2019, In: BMC Medical Informatics and Decision Making. 19 , p. 108

Effect of physical exercise on cognitive function and brain measures after chemotherapy in patients with breast cancer (PAM study):protocol of a randomised controlled trial

Witlox Lenja, Schagen Sanne B, de Ruiter Michiel B, Geerlings Mirjam I, Peeters Petra H M, Koevoets Emmie W, van der Wall Elsken, Stuiver Martijn, Sonke Gabe, Velthuis Miranda J, Palen Job A M van der, Jobsen Jan J, May Anne M, Monninkhof E M 1 jun 2019, In: BMJ Open. 9

All Research Output (205)