prof. dr. L.J. (Jaap) Kappelle Full Professor

Neurology & Neurosurgery

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Research programs

Biography
Side Activities
Research Output

Biography

Jaap Kappelle was registered as a clinical neurologist in 1988. He obtained his PhD degree in Utrecht (1990) with Jan van Gijn. He carried out postdoctoral research at the University of Iowa, Iowa City, USA (1991) and the John P. Robarts Research Institute, London (Ontario) Canada (1998). He was appointed assistant professor at the University Utrecht in 1988, associate professor in 1994 and full professor in 2000. He is head of the department of cerebrovascular diseases of the University Medical Centre (UMC) Utrecht.

His research is embedded in the UMC Utrecht Stroke Centre in close collaboration with the departments of neurosurgery, radiology, vascular medicine, vascular surgery, rehabilitation, clinical epidemiology, primary health care and neuropsychology. The current line of research concerns stroke, in particular the diagnosis, treatment and prognosis of patients with TIA or ischaemic stroke. As part of his research activities he is member of steering committees of reserrch proframs embedded in 'Cardio-Vasculair Onderzoek Nederland'.

He is a member of the education committee if the Dutch Neurological Society and Dutch delegate for stroke of the European Association of Neurology. Besides his regular education duties in the UMC Utrecht, he is memeber of the board of supervisors of the Medical student Societÿ 'MSFU SAMS)

Jaap Kappelle is member elect of the European Stroke Council and premium professional silver heart memeber of the American Heart Associatiuon. He is member of the board of directors of the Dutch Vascular Society and member of the scientific committee of ‘CardioVasculair Onderzoek Nederland’ founder of the Dutch Neurovascular Society. He is also a member of the 'Nederlandse Vereniging voor Medsich Specialistische Rappoprtages and serves as neutral expert for different courts, insurance companies and health care organisations.

Research line

Cerebrovascular diseases

publications

https://www.ncbi.nlm.nih.gov/pubmed/?term=Kappelle+LJ

Side Activities

As mentioned in the Biography.

Research Output

Intracranial Atherosclerotic Burden on 7T MRI Is Associated with Markers of Extracranial Atherosclerosis: The SMART-MR Study

Zwartbol M. H. T., Geerlings M. I., Ghaznawi R., Hendrikse J., van der Kolk A. G., Asselbergs F. W., Nathoe H. M., de Borst G. J., Bots M. L., Emmelot M. H., de Jong P. A., Leiner T., Lely A. T., van der Kaaij N. P., Kappelle L. J., Ruigrok Y. M., Verhaar M. C., Visseren F. L. J., Westerink J., 5 Dec 2019 In: American Journal of Neuroradiology. 40, p. 2016-2022 7 p.

Frequent Cognitive Impairment in Patients With Disorders Along the Heart-Brain Axis

Hooghiemstra Astrid M, Leeuwis Anna E, Bertens Anne Suzannne, Biessels Geert Jan, Bots Michiel L, Brunner-La Rocca Hans-Peter, Greving Jacoba P, Kappelle L Jaap, van Oostenbrugge Robert J, van Rossum Albert C, van der Flier Wiesje M, 5 Nov 2019 In: Stroke. 50, p. 3369-3375 7 p.

Nonfocal Transient Neurological Attacks Are Associated With Cerebral Small Vessel Disease

Oudeman Eline A, Greving Jacoba P, Van den Berg-Vos Renske M, Biessels Geert Jan, Bron Esther E, van Oostenbrugge Robert, de Bresser Jeroen, Kappelle L Jaap, 22 Oct 2019 In: Stroke. 50, p. 3540-3544 5 p.

Response by Dolmans et al to Letter Regarding Article, "Diagnostic Accuracy of the Explicit Diagnostic Criteria for Transient Ischemic Attack: A Validation Study"

Dolmans L Servaas, Rutten Frans H, Kappelle L Jaap 18 Oct 2019 In: Stroke. 50, p. e336

Serum biomarkers in patients suspected of transient ischaemic attack in primary care: A diagnostic accuracy study

Dolmans Louis Servaas, Rutten Frans, Bartelink Marie Louise E.L., Van Dijk Ewoud J., Nederkoorn Paul J., Kappelle Jaap, Hoes Arno W. 17 Oct 2019 In: BMJ Open. 9 9 p.

Normal-range thyroid-stimulating hormone levels and cardiovascular events and mortality in type 2 diabetes

de Vries Tamar I., de Valk Harold W., van der Graaf Yolanda, de Borst Gert J., Cramer Maarten J.M., Jaap Kappelle L., Visseren Frank L.J., Westerink Jan 16 Oct 2019 In: Diabetes Research and Clinical Practice. 157

Transcranial Doppler 24 Hours after Carotid Endarterectomy Accurately Identifies Patients Not at Risk of Cerebral Hyperperfusion Syndrome

Fassaert Leonie M.M., Immink Rogier V., van Vriesland Daniël J., de Vries Jean Paul P.M., Toorop Raechel J., Kappelle L. Jaap, Westerink Jan, Tromp Selma C., de Borst Gert J. 1 Sep 2019 In: European Journal of Vascular and Endovascular Surgery. 58, p. 320-327 8 p.

Candidate Biomarkers for the Diagnosis of Transient Ischemic Attack: A Systematic Review

Dolmans L. Servaas, Rutten Frans H., Koenen Niels C.T., Bartelink Marie Louise E.L., Reitsma Johannes B., Kappelle L. Jaap, Hoes Arno W. 30 Aug 2019 In: Cerebrovascular Diseases. 47, p. 207-216 10 p.

The Dutch Parelsnoer Institute Cerebrovascular Disease Initiative: A retrospective study of the effects of integrating clinical care and research on costs and quality of care in patients with ischaemic stroke

Mensing Liselore A., Kappelle Jaap, Buijs Julie E., Luijckx Gert Jan, Koffijberg Hendrik, Zielhuis Gerhard A., Ruigrok Ynte M. 27 Aug 2019 In: BMJ Open. 9

Determinants of Patient Delay in Transient Ischemic Attack

Dolmans L. Servaas, Hoes Arno W., Bartelink Marie Louise E.L., Kappelle L. Jaap, Rutten Frans H. 1 Aug 2019 In: European Neurology. 81, p. 139-144 6 p.

All Research Output (813)