dr. J.J.C. (Joost) Verhoeff
Associate Professor - medical
- Radiotherapy (research)
- Department of Radiotherapy
Contact
Biography
My lab's mission is to redefine Standard Radiotherapy
As radiation oncologists, we treat cancer patients with high precision radiotherapy. The UMC Utrecht has the right caring team and right machinery for this (2x MRI-linac, 10x CT-linac). My lab's goal is providing the best cancer treatment for each patient. Some patients want to live as long as possible regardless of treatment side effects, others want quality of life. To find balance is key.
The UMC Utrecht department of radiation oncology is a terrific place to do clinical research, as it is even the birthplace of the MRI-linac. Next, the Radiation Oncology department harbours 2 1.5T MRI systems, a 3.0T MRI and soon a 7.0T MRI and a PET-MRI.
Joost subspecialized in treatment of brain tumors and lung cancer. About half of his time he spends on research as associate professor.
Brain tumors:
- Increasing quality of life by shorter but better focused radiation treatment
- Increasing overall survival by combining better treatment modalities
Brain metastases:
- Finding best treatments for each specific patient: personalized medicine.
- Increasing quality of life by incorporating MR-guided treatment post operative (MRI-linac)
- Coimbra brain metastasis prospective cohort
Lung cancer:
- Better predicting patient survival and toxicity by deep learning
- Increasing quality of life by incorporating MR-guided treatment (MR-Linac)
- U-color prospective cohort
Cardiac Ablative SBRT:
- In collaboration with 30 other European hospitals we develop strategies to treat Ventricular Tachycardia in the STOPSTORM.eu framework.
Postdocs:
- Szabolcs David PhD (brain tumors)
- Jacqueline Pomp MD PhD (lung cancer and deep learning)
PhD students:
- Steven Nagtegaal MD (brain tumors)
- Wouter van Amsterdam MD (deep learning, lung cancer)
- Eva van Grinsven MSc (brain tumors)
- Arthur van der Boog BS (brain tumors)
- Belle van Duin MD (melanoma)
Residents radiation oncology performing research:Marnix Rasing MD (lung cancer)
- Laura Merckel MD PhD (MRI-linac lung cancer)
- Joyce Lodeweges MD (lung cancer)
- Max Peters MD PhD (epidemiology, lung cancer)
- Peter van Rossum MD PhD (MRI-linac, epidemiology, lung cancer)
- Pim Damen MD (immunotherapies)
- Janneke van der Stap MANP (lung cancer)
Students (medical, biomedical, informatics):
- Alexander van Hulsbergen BS (brain tumors)
- Daniel Versnel (brain tumors)
- Myra van Laar (lung cancer)
- Sjors Witteveen (lung cancer)
- Marc Pijper (lung cancer)
- Bas Arends (deep learning for spine tumor treatment)
- Anouk Steennis (brain metastases)
- Hajo Boersma (psychiatric disorders and radiotherapy)
- Eliza van Wulfften Palthe (brain metastases)
Full list of publications on PubMed: click here (automatic list is incomplete)
Research Output (53)
Impact of body fat distribution and sarcopenia on the overall survival in patients with spinal metastases receiving radiotherapy treatment:a prospective cohort study
Pielkenrood B J, van Urk P R, van der Velden J M, Kasperts N, Verhoeff J J C, Bol G H, Verkooijen H M, Verlaan J J mrt 2020, In: Acta Oncologica. 59 , p. 291-297 7 p.
Eliminating biasing signals in lung cancer images for prognosis predictions with deep learning
van Amsterdam W. A. C., Verhoeff J. J. C., de Jong P. A., Leiner T., Eijkemans M. J. C. 10 dec 2019, In: NPJ DIGITAL MEDICINE. 2 , p. 122
Preoperative Prediction of Incomplete Resection in Non-Small Cell Lung Cancer: An Externally Validated Clinical Nomogram
Rasing M., Peters M., Moreno A., Hofman E., Herder J., Welvaart P., Schramel Franz M N H, Lodeweges J., Lin Steven H, Verhoeff J., Van Rossum P. okt 2019, In: Journal of Thoracic Oncology. 14 , p. S623-S623
Significance of Programmed Death Receptor Ligand One Expression in Brain Metastases of Non-Small Cell Lung Carcinoma
Hulsbergen A., Mammi M., Nagtegaal S., Verhoeff J., Smith T., Phillips J. 1 sep 2019, In: International Journal of Radiation Oncology Biology Physics. 105 , p. E78-E78
A Multi-Institutional Estimation of Interobserver Variability in Glioblastoma Delineation in the EORTC-1709-BTG /CCTG CE.8 Trial
Kaidar-Person O., Saez J., Andratschke N., de Abrunhosa Branquinho A. N., Clementel E., Corning C., Hurkmans C., Monti A. F., Roth P., Verhoeff J., Dhermain F. 1 sep 2019, In: International Journal of Radiation Oncology Biology Physics. 105 , p. E617-E618
Comparing survival predicted by the diagnosis-specific Graded Prognostic Assessment (DS-GPA) to actual survival in patients with 1-10 brain metastases treated with stereotactic radiosurgery
Nagtegaal Steven, Claes An, Suijkerbuijk Karijn, Schramel Franz, Snijders Tom, Verhoeff Joost 1 sep 2019, In: Radiotherapy & Oncology. 138 , p. 173-179 7 p.
A Multi-Institutional Estimation of Interobserver Variability in Glioblastoma Treatment Planning in the EORTC-1709-BTG / CCTG CE.8 trial
Monti A. F., de Abrunhosa Branquinho A. N., Andratschke N., Clementel E., Corning C., Dhermain F., Hurkmans C., Kaidar-Person O., Roth P., Saez J., Verhoeff J. 1 sep 2019, In: International Journal of Radiation Oncology Biology Physics. 105 , p. E619-E619
Any Radiation Dose to the Hippocampus Leads to Local Volume Loss in a Dose-Time-Dependent Way
Nagtegaal S., David S., Philippens M., Leemans A., Verhoeff J. 1 sep 2019, In: International Journal of Radiation Oncology Biology Physics. 105 , p. E104-E105
Occurrence of an Abscopal Radiation Recall Phenomenon in a Glioblastoma Patient Treated with Nivolumab and Re-Irradiation
Van Seggelen Wouter O., De Vos Filip Y., Röckmann Heike, Van Dijk Marijke R., Verhoeff Joost J.C. 1 sep 2019, In: Case Reports in Oncology. 12 , p. 896-900 5 p.
Brain and Head-and-Neck MRI in Immobilization Mask:A Practical Solution for MR-Only Radiotherapy
Mandija Stefano, D'Agata Federico, Navest Robin J M, Sbrizzi Alessandro, Tijssen Rob H N, Philippens Marielle E P, Raaijmakers Cornelis P J, Seravalli Enrica, Verhoeff Joost J C, Lagendijk Jan J W, van den Berg Cornelis A T 17 jul 2019, In: Frontiers in oncology. 9