dr. J.J.C. (Joost) Verhoeff
- Radiotherapy (research)
- Department of Radiotherapy
Research Programs
Biography
Biography
My lab's mission is to redefine Standard Radiotherapy
As radiation oncologists, we want to treat cancer patients with high precision radiotherapy. The UMC Utrecht has the right caring team and right machinery for this (2x MRI-linac, 10x CT-linac). My lab's goal is providing the best cancer treatment for each patient. Some patients want to live as long as possible regardless of treatment side effects, others want quality of life. To find balance is key.
The UMC Utrecht department of radiation oncology is a terrific place to do clinical research, as it is even the birthplace of the MRI-linac. Next, the Radiation Oncology department harbours 2 1.5T MRI systems, a 3.0T MRI. a 7.0T MRI and a MRI/PET scanner.
Joost Verhoeff subspecialized in treatment of brain tumors and lung cancer. About half of his time he spends on research as associate professor.
Brain tumors:
- Increasing quality of life by shorter but better focused radiation treatment
- Increasing overall survival by combining better treatment modalities
- Principal Investigator of ZonMW funded GOLD trial (dutch info), 30x2Gy+TMZ versus 6x6Gy+TMZ for primary GBM
- Principal Investigator of KWF funded RISinG trial (Dutch info), 10x3.4Gy versus 4x7.5Gy for recurrent GBM
Brain metastases:
- Finding best treatments for each specific patient: personalized medicine.
- Increasing quality of life by incorporating MR-guided treatment post operative (MRI-linac)
- Coimbra brain metastasis prospective cohort (website)
Lung cancer:
- Better predicting patient survival and toxicity by smart analyses
- Increasing quality of life by incorporating MR-guided treatment (MR-Linac)
- U-color prospective cohort, for all lung cancer patients that receive radiotherapy
Cardiac Ablative SBRT:
- In collaboration with 30 other European hospitals we develop strategies to treat Ventricular Tachycardia in the STOPSTORM.eu framework (Principal Investigator, EU H2020 grant).
Postdocs:
- Szabolcs David PhD (brain tumors, imaging)
- Jacqueline Pomp MD PhD, radiation oncologist, (lung cancer and deep learning)
- Peter van Rossum MD PhD MSc, resident radiation oncologist (MRI-linac, epidemiology, lung cancer)
PhD students:
- Steven Nagtegaal MD (brain tumors, cognitive changes)
- Wouter van Amsterdam MD (deep learning, lung cancer)
- Eva van Grinsven MSc (neuro-psychology, brain tumors)
- Arthur van der Boog BS (brain tumors, clinical trials)
- Belle van Duin MD (melanoma, imaging, pathology)
Residents radiation oncology performing research:
- Laura Merckel MD PhD (MRI-linac lung cancer)
- Marnix Rading MD (lung cancer)
- Joyce Lodeweges MD (lung cancer)
- Max Peters MD PhD MSc (epidemiology, lung cancer)- Pim Damen MD (immunotherapies)
- Janneke van der Stap MANP (lung cancer)
Students (medical, biomedical, informatics):
- Eliza van Wulfften Palthe (brain metastases)
- Anouk Steennis (brain tumors)
- Victor Wasser (brain tumor imaging)
- Salah Gasle (brain tumor imaging)
- Michelle Sierts (brain tumors)
- Karlijn Smitt (brain tumors)
- Mathijs Tomassen (lung cancer)
- Hugo van Joolingen (lung cancer)
- Céline Bogers (lung cancer)
- Anne van der Tuin (lung cancer)
- Eva Swinkels (lung cancer)
- Lucie Egberink (lung cancer)
- Bas Arends (deep learning for spine tumor treatment)
- Jasper Hennecken (spinal imaging)
- Hajo Boersma (psychiatric disorders and radiotherapy)
Former group members (medical, biomedical, informatics):
- Ali Ghannam (brain metastases cohort)
- Emma Nessen (brain metastases)
- Marc Pijper (lung cancer)
- Cathalijne Post (brain tumors)
- Robin Schuijlenburg (brain tumors)
- Merel Kraak (lung cancer)
- Suzanne Vellinga (lung cancer)
- Netanja Harlianto (lung cancer)
- Yannic Hanekamp (Covid treatment)
- Sjors Wagemakers (pain meassurement)
- Max van Essen (brain tumors)
- Chris Hammerstein (survival analyses)
Full list of publications on PubMed: click here (automatic list is incomplete)
Research Output (66)
Bartels Marcia M T J, Verpalen Inez M, Ferrer Cyril J, Slotman Derk J, Phernambucq Erik C J, Verhoeff Joost J C, Eppinga Wietse S C, Braat Manon N G J A, van den Hoed Rolf D, van 't Veer-Ten Kate Miranda, de Boer Erwin, Naber Harry R, Nijholt Ingrid M, Bartels Lambertus W, Bos Clemens, Moonen Chrit T W, Boomsma Martijn F, Verkooijen Helena M mrt 2021, In: Clinical and translational radiation oncology. 27 , p. 57-63 7 p.
Nagtegaal Steven H J, David Szabolcs, Philippens Marielle E P, Snijders Tom J, Leemans Alexander, Verhoeff Joost J C jan 2021, In: Clinical and translational radiation oncology. 26 , p. 35-41 7 p.
Hanekamp Yannic N, Giordano James, Hanekamp Jaap C, Khan Mohammad K, Limper Maarten, Venema Constantijn S, Vergunst Samuel D, Verhoeff Joost J C, Calabrese Edward J 22 sep 2020, In: Dose-response : a publication of International Hormesis Society. 18
Nagtegaal S H J, Hulsbergen A F C, van Dorst E B L, Kavouridis V K, Jessurun C A C, Broekman M L D, Smith T R, Verhoeff J J C sep 2020, In: Clinical and translational radiation oncology. 24 , p. 11-15 5 p.
Tseng Chia-Lin, Stewart James, Whitfield Gillian, Verhoeff Joost J C, Bovi Joseph, Soliman Hany, Chung Caroline, Myrehaug Sten, Campbell Mikki, Atenafu Eshetu G, Heyn Chinthaka, Das Sunit, Perry James, Ruschin Mark, Sahgal Arjun 29 aug 2020, In: Journal of Neuro-Oncology. 149 , p. 305-314 10 p.
Rasing Marnix J A, Peters Max, Moreno Amy C, Hofman Erik F N, Herder Gerarda J M, Welvaart Pim W N, Schramel Franz M N H, Lodeweges Joyce E, Lin Steven H, Verhoeff Joost J C, van Rossum Peter S N 31 jul 2020, In: Annals of Thoracic Surgery. 111 , p. 1052-1058 7 p.
van Laar Myra, van Amsterdam Wouter A C, van Lindert Anne S R, de Jong Pim A, Verhoeff Joost J C 22 jul 2020, In: Radiotherapy & Oncology. 151 , p. 152-175 24 p.
Nagtegaal Steven H J, David Szabolcs, Snijders Tom J, Philippens Marielle E P, Leemans Alexander, Verhoeff Joost J C 10 jul 2020, In: Neuro-oncology advances. 2 8 p.
Deroose Christophe M, Lecouvet Frédéric E, Collette Laurence, Oprea-Lager Daniela E, Kunz Wolfgang G, Bidaut Luc, Verhoeff Joost J C, Caramella Caroline, Lopci Egesta, Tombal Bertrand, de Geus-Oei Lioe-Fee, Fournier Laure, Smits Marion, deSouza Nandita M 12 jun 2020, In: European Journal of Nuclear Medicine and Molecular Imaging. 47 , p. 2054-2058 5 p.
Maspero Matteo, Houweling Antonetta C., Savenije Mark H.F., van Heijst Tristan C.F., Verhoeff Joost J.C., Kotte Alexis N.T.J., van den Berg Cornelis A.T. apr 2020, In: Physics and Imaging in Radiation Oncology. 14 , p. 24-31 8 p.