dr. J.J.C. (Joost) Verhoeff Assistant Professor - medical

Radiotherapy (research)

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Research Output

Biography

I want to redefine Standard Radiotherapy

As a radiation oncologist, I treat cancer patients with radio-active beams. My focus is providing the best cancer treatment. Some patients want to live as long as possible regardless of treatment side effects, others want quality of life. To find balance is key.

The UMC Utrecht department of radiation oncology is a terrific place to spend my days, as it is the birthplace of the MRI-linac.

I subspecialized in treatment of brain tumors and lung cancer. About half of my time I spend on research.

Brain tumors:

Increasing quality of life by shorter but better focused radiation treatment
Increasing overall survival by combining better treatment modalities

Brain metastases:

Finding best treatments for each specific patient: personalized medicine.
Increasing quality of life by incorporating MR-guided treatment post operative (MRI-linac)

Lung cancer:

Better predicting patient survival by deep learning
Increasing quality of life by incorporating MR-guided treatment (MR-Linac)

Cardiac Ablative SBRT:

In collaboration with other hospitals we develop strategies to treat Ventricular Tachycardia

PhD students:

Steven Nagtegaal MD (brain tumors)
Wouter van Amsterdam MD (deep learning, lung cancer)
Eva van Grinsven MSc (brain tumors)
Louis van Harten MS (deep learning, brain tumors)

Residents radiation oncology performing research:

Marnix Rasing MD (lung cancer)
Laura Merckel MD PhD (MRI-linac lung cancer)
Joyce Lodeweges MD (lung cancer)
Max Peters MD PhD (epidemiology, lung cancer)
Peter van Rossum MD PhD (MRI-linac, epidemiology, lung cancer)
Pim Damen MD (immunotherapies)
Christa Gadella MD (brain tumors)
Jonna van Vulpen MD PhD (cardiac ablative SBRT)

Students:

Arthur van der Boog BS (brain tumors)
Alexander van Hulsbergen BS (brain tumors)
Daniel Versnel (brain tumors)
Myra van Laar (lung cancer)
Robin Schuijlenburg (brain tumors)

Research Output

A Systematic Review of Devices and Techniques that Objectively Measure Patients' Pain

Wagemakers Sjors H., van der Velden Joanne M., Gerlich A. Sophie, Hindriks-Keegstra Alinde W., van Dijk Jacqueline F.M., Verhoeff Joost J.C. 1 Jan 2019 In: Pain Physician. 22, p. 1-13 13 p.

MR-Only Brain Radiation Therapy: Dosimetric Evaluation of Synthetic CTs Generated by a Dilated Convolutional Neural Network

Dinkla Anna M., Wolterink Jelmer M., Maspero Matteo, Savenije Mark H.F., Verhoeff Joost J.C., Seravalli Enrica, Išgum Ivana, Seevinck Peter R., van den Berg Cornelis A.T. 22 May 2018 In: International Journal of Radiation Oncology Biology Physics. 102, p. 801-812

Survival after whole brain radiotherapy for brain metastases from lung cancer and breast cancer is poor in 6325 Dutch patients treated between 2000 and 2014

Jeene Paul M, de Vries Kim C, van Nes Johanna G H, Kwakman Johannes J M, Wester Gerda, Rozema Tom, Braam Pètra M, Zindler Jaap D, Koper Peter, Nuyttens Joost J, Vos-Westerman Hanneke A, Schmeets Ilona, Niël Charles G H J, Hutschemaekers Stefan, Van Der Linden Yvette M., Verhoeff Joost J C, Stalpers Lukas J A May 2018 In: Acta Oncologica. 57, p. 637-643

OC-0293: Dosimetric evaluation of deep learning based synthetic-CT generation for MR-only brain radiotherapy

Dinkla A. M., Wolterink J. M., Maspero M., Savenije M. H. F., Verhoeff J. J. C., Isgum I., Seevinck P. R., Lagendijk J. J. W., Van den Berg C. A. T. Apr 2018 In: Radiotherapy & Oncology. 127, p. S151-S151

Ischemic stroke after radiation therapy for pituitary adenomas: a systematic review

van Westrhenen A., Muskens I. S., Verhoeff J. J.C., Smith T. R.S., Broekman M. L.D. 1 Oct 2017 In: Journal of Neuro-Oncology. 135, p. 1-11

Stereotactic radiosurgery versus whole-brain radiotherapy after intracranial metastasis resection: A systematic review and meta-analysis

Lamba Nayan, Muskens Ivo S, DiRisio Aislyn C, Meijer Louise, Briceno Vanessa, Edrees Heba, Aslam Bilal, Minhas Sadia, Verhoeff Joost J.C., Kleynen Catharina E. , Smith Timothy R, Mekary Rania A, Broekman Marike L. 24 Jun 2017 In: Radiation Oncology [E]. 12

In vivo phage display screening for tumor vascular targets in glioblastoma identifies a llama nanobody against dynactin-1-p150^Glued

van Lith Sanne A M, Roodink Ilse, Verhoeff Joost J C, Mäkinen Petri I., Lappalainen Jari P., Ylä-Herttuala Seppo, Raats Jos, van Wijk Erwin, Roepman Ronald, Letteboer Stef J., Verrijp Kiek, Leenders William P J 2016 In: Oncotarget. 7, p. 71594-71607 14 p.

A 43-year-old female with multifocal cerebral lesions

Nieuwenhuis Marieke B B, Van Der Salm Sandra M A, Verhoeff Joost J C, Van Der Kooi Anneke J., Slavujecvic-Letic Ivana, Pals Steven T., Vos Josephine M I 1 May 2015 In: Brain Pathology. 25, p. 371-372 2 p.

Bevacizumab in combination with radiotherapy and temozolomide for patients with newly diagnosed glioblastomamultiforme

Van Linde Myra E., Verhoeff Joost J C, Richel Dirk J., Van Furth Wouter R., Reijneveld Jaap C., Verheul Henk M W, Stalpers Lukas J A 12 Jan 2015 In: Oncologist. 20, p. 107-108 2 p.

All Research Output (9)

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Research Output

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