prof. dr. R. de Bree MD

Full Professor

  • Department of Head and Neck Oncology
  • MS Hoofd-Hals Chirurgische Oncologie

prof. dr. R. de Bree MD

Research Programs


Remco de Bree (1966) studied medicine in Utrecht, The Netherlands. His PhD research on the VU University Medical Center was about the clinical application of radiolabelled monoclonal antibodies in head and neck cancer patients. In 1999 he finished his training in otolaryngology. Thereafter, he was a fellow in head and neck surgery for 2 years at the same hospital, where he worked as a head and neck surgeon for 14 years and became full professor for clinical oncological research at the department of otolaryngology - head and neck surgery in 2006. Since 2015 he is full professor and head of the department of Head and Neck Surgical Oncology at the UMC Utrecht Cancer Center of the University Medical Center Utrecht, The Netherlands. His special interests are the clinical applications and improvements of diagnostic imaging techniques, sentinel node procedure, quality of life and reconstructive surgery in head and neck cancer patients. He has authored and co-authored over 200 articles in international peer-reviewed journals. He was the principal investigator and coordinator of several (inter)national multicenter trials, is a member of the Research steering committee of the Dutch Head and Neck Society (NWHHT), is a member of several editorial boards and member of the Cochrane Ear, Nose & Throat Disorders Group. 

Side Activities

  • Lid Clinical Audit Board van de Dutch Head and Neck Audit (DHNA)

    Lid Scientific Advisory Board Dutch Oncology Research Platform (DORP)

    Voorzitter Research stuurgroep Nederlandse  werkgroep Hoofd-Hals Tumoren (NWHHT)

    Voorzitter Herziening richtlijn Hoofd-Halsoncologie

    Lid kerngroep richtlijncommissie Nederlandse Werkgroep Hoofd-Hals Tumoren (NWHHT)

    Lid Algemeen Bestuur Patiëntenvereniging Hoofd-Hals (PVHH)

Fellowship and Awards

  • 1996 Best PhD thesis Dutch Otolaryngology Society

Research Output (273)

Considerations for environmentally sustainable head and neck surgical oncology practice

Sanabria Alvaro, Kowalski Luiz P, Nixon Iain J, Shaha Ashok, De Bree Remco, Mäkitie Antti A, Rinaldo Alessandra, Ferlito Alfio 12 sep 2020, In: American journal of otolaryngology. 41 , p. 102719

Predictive value of quantitative 18F-FDG-PET radiomics analysis in patients with head and neck squamous cell carcinoma

Martens Roland M, Koopman Thomas, Noij Daniel P, Pfaehler Elisabeth, Übelhör Caroline, Sharma Sughandi, Vergeer Marije R, Leemans C René, Hoekstra Otto S, Yaqub Maqsood, Zwezerijnen Gerben J, Heymans Martijn W, Peeters Carel F W, de Bree Remco, de Graaf Pim, Castelijns Jonas A, Boellaard Ronald 7 sep 2020, In: EJNMMI Research. 10 , p. 102

Sentinel lymph node detection in oral cancer: a within-patient comparison between [Tc-99m]Tc-tilmanocept and [Tc-99m]Tc-nanocolloid:a within-patient comparison between [99mTc]Tc-tilmanocept and [99mTc]Tc-nanocolloid

den Toom Inne J, Mahieu Rutger, van Rooij Rob, van Es Robert J J, Hobbelink Monique G G, Krijger Gerard C, Tijink Bernard M, de Keizer Bart, de Bree Remco 25 aug 2020, In: European Journal of Nuclear Medicine and Molecular Imaging.

Elective Neck Dissection or Sentinel Lymph Node Biopsy in Early Stage Oral Cavity Cancer Patients:The Dutch Experience

den Toom Inne J, Boeve Koos, Lobeek Daphne, Bloemena Elisabeth, Donswijk Maarten L, de Keizer Bart, Klop W Martin C, Leemans C René, Willems Stefan M, Takes Robert P, Witjes Max J H, de Bree Remco 3 jul 2020, In: Cancers. 12

Prostate-specific membrane antigen (PSMA) expression in adenoid cystic carcinoma of the head and neck

Klein Nulent Thomas J W, Valstar Matthijs H, Smit Laura A, Smeele Ludwig E, Zuithoff Nicolaas P A, de Keizer Bart, de Bree Remco, van Es Robert J J, Willems Stefan M 5 jun 2020, In: BMC Cancer. 20 9 p.

Staging and grading of oral squamous cell carcinoma:An update

Almangush Alhadi, Mäkitie Antti A, Triantafyllou Asterios, de Bree Remco, Strojan Primož, Rinaldo Alessandra, Hernandez-Prera Juan C, Suárez Carlos, Kowalski Luiz P, Ferlito Alfio, Leivo Ilmo 20 mei 2020, In: Oral Oncology. 107 6 p.

Incidence of Occult Lymph Node Metastasis in Primary Larynx Squamous Cell Carcinoma, by Subsite, T Classification and Neck Level:A Systematic Review

Sanabria Alvaro, Shah Jatin P, Medina Jesus E, Olsen Kerry D, Robbins K Thomas, Silver Carl E, Rodrigo Juan P, Suárez Carlos, Coca-Pelaz Andrés, Shaha Ashok R, Mäkitie Antti A, Rinaldo Alessandra, de Bree Remco, Strojan Primož, Hamoir Marc, Takes Robert P, Sjögren Elisabeth V, Cannon Trinitia, Kowalski Luiz P, Ferlito Alfio 24 apr 2020, In: Cancers. 12 16 p.

Detecting Bone Invasion of the Maxilla by Oral Squamous Cell Carcinoma:Diagnostic Accuracy of Preoperative Computed Tomography Versus Magnetic Resonance Imaging

Bernard Slieker Fons Joeri, Dankbaar Jan Willem, de Bree Remco, Van Cann Ellen Maria 23 apr 2020, In: Journal of Oral and Maxillofacial Surgery. 78 , p. 1645-1652 8 p.

COVID-19 pandemic:effects and evidence-based recommendations for otolaryngology and head and neck surgery practice

Kowalski Luiz P, Sanabria Alvaro, Ridge John A, Ng Wai Tong, de Bree Remco, Rinaldo Alessandra, Takes Robert P, Mäkitie Antti A, Carvalho Andre L, Bradford Carol R, Paleri Vinidh, Hartl Dana M, Poorten Vincent Vander, Nixon Iain J, Piazza Cesare, Lacy Peter, Rodrigo Juan P, Guntinas-Lichius Orlando, Mendenhall William M, D'Cruz Anil, Lee Anne W M, Ferlito Alfio 9 apr 2020, In: Head & neck. 42 , p. 1259-1267 9 p.

Humour and laughing in patients with prolonged incurable cancer:an ethnographic study in a comprehensive cancer centre

Buiting Hilde M, de Bree Remco, Brom Linda, Mack Jennifer W, van den Brekel Michiel W M 6 apr 2020, In: Quality of Life Research. 29 , p. 2425-2434 10 p.

All Research Output (273)