dr. S.G. (Sjoerd) Elias

dr. S.G. (Sjoerd) Elias

Associate Professor
dr. S.G. (Sjoerd) Elias
  • Epi Kanker Team C
  • Julius Center Research Program Cancer
  • Julius Center Research Program Cancer

Research Programs

Strategic Program Cancer



I obtained my MSc in Clinical Epidemiology at the Netherlands Institute for Health Sciences (2002), and my PhD at Utrecht University (2003). Following graduation from Medical School in 2005 I worked as a resident in radiology (Gelre Ziekenhuizen Apeldoorn, the Netherlands, 2006-2007). A personal Dutch Cancer Society Research Fellowship (2009-2013) enabled me to work as a visiting scientist at the Molecular Imaging Program at Stanford (professor SS Gambhir), the Department of Radiology and Biomedical Imaging at the University of California San Francisco (professor NM Hylton), and the Department of Molecular Pathology at the Netherlands Cancer Institute (professor LJ van't Veer). Since 2008, I work as a Clinical Epidemiologist in the research programs Cancer and Methodology at the Julius Center for Health Sciences and Primary Care, since 2018 as Associate Professor. Furthermore, I have more than ten years of experience in teaching and coordinating courses in clinical epidemiology, both nationally as well as internationally. Since 2020 I am coordinator of the PhD program Clinical and Translational Oncology, and since 2021 I am coordinator of the Research Program Cancer and management team member of the Epidemiology department of the Julius Center, as well as board member of the UMC Utrecht Strategic Program Cancer.

Interests and Focus

My main research focus is on the clinical evaluation and translation of biomarkers, particularly for cancer classification (i.e. diagnostic, prognostic, and predictive markers). These markers include emerging imaging technologies such as molecular imaging, omics-based tests, and organoids. I have both experience in preclinical research as well as applied clinical science, and have expertise and experience in the design and analysis of studies spanning all (translation) phases of biomarker development, as well as treatment studies (from phase I through phase III).

Side Activities

- Board member of the UMC Utrecht Strategic Program Cancer.

- Coordinator of the Research Program Cancer of the Julius Center.

- Coordinator of the PhD program Clinical and Translational Oncology.

- Coordinator of the SUMMA course "Wetenschappelijke Vorming - Onderzoeksmethodologie" ("applied clinical research").

- Coordinator of the MSc Epidemiology course "Advanced Topics in Causal Research: Confounding and Effect-Modification".

- Member of the Internal Review Committee Exploration of the Dutch Cancer Society.

- Member of the Dutch Association for Epidemiology (Vereniging voor Epidemiologie), Registration as Senior Epidemiologist (B) (SMBWO, 2006).

Fellowship and Awards

2016-2017: Jury member of the Talma Eykman award, UMC Utrecht.

2016-2017: Jury member of the Frits de Waard Penning, UMC Utrecht.

2014: Epidemiology teacher of the year, Epidemiology department, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht.

2014: Voted best lecturer of the year by the Selective Utrecht Medical Master program students, Utrecht University.

2013-2016: Methodologist of the Medical Ethical Review Board of the UMC Utrecht.

2013: UMC Utrecht Research Talent Program.

2012: Invitee, 2nd Inspire2Live annual conference at the Royal Netherlands Academy of Arts and Sciences (meeting of talented young international cancer scientists).

2011: René Vogels Foundation travel grant.

2009: Dutch Cancer Society Research Fellowship (four year personal grant).

Research Output (169)

Contralateral parenchymal enhancement on MRI is associated with tumor proteasome pathway gene expression and overall survival of early ER+/HER2-breast cancer patients

Ragusi Max A A, Bismeijer Tycho, van der Velden Bas H M, Loo Claudette E, Canisius Sander, Wesseling Jelle, Wessels Lodewyk F A, Elias Sjoerd G, Gilhuijs Kenneth G A 2 nov 2021, In: The Breast. 60 , p. 230-237 8 p.

Sixty-Day Mortality of Patients With Metastatic Colorectal Cancer Randomized to Systemic Treatment vs Primary Tumor Resection Followed by Systemic Treatment:The CAIRO4 Phase 3 Randomized Clinical Trial

van der Kruijssen Dave E W, Elias Sjoerd G, Vink Geraldine R, van Rooijen Karlijn L, 't Lam-Boer Jorine, Mol Linda, Punt Cornelis J A, de Wilt Johannes H W, Koopman Miriam, 6 okt 2021, In: JAMA Surgery. 156 , p. 1093-1101 9 p.

Role of Up-Front Primary Tumor Resection and Tumor Sidedness in the Survival of Synchronous Metastatic Colon Cancer Patients

van der Kruijssen Dave E W, van Rooijen Karlijn L, Kurk Sophie A, de Wilt Johannes HW, Punt Cornelis J A, Vink Geraldine R, Elias Sjoerd G, Koopman Miriam 28 jul 2021, In: Digestive Surgery. 38 , p. 283-289 7 p.

Interaction Between Primary Tumor Resection, Primary Tumor Location, and Survival in Synchronous Metastatic Colorectal Cancer:A Population-Based Study

van der Kruijssen Dave E W, Brouwer Nelleke PM, van der Kuil Auke J S, Verhoeven Rob H A, Elias Sjoerd G, Vink Geraldine R, Punt Cornelis J A, de Wilt Johannes H W, Koopman Miriam 1 jul 2021, In: American Journal of Clinical Oncology. 44 , p. 315-324 10 p.

Prognostic value of breast MRI characteristics before and during neoadjuvant endocrine therapy in patients with ER+/HER2- breast cancer

Ragusi Max Aa, Winter-Warnars Gonneke Ao, Wesseling Jelle, Linn Sabine C., Beets-Tan Regina G., van der Velden Bas Hm, Elias Sjoerd G., Gilhuijs Kenneth Ga, Loo Claudette E. 1 jul 2021, In: The British journal of radiology. 94 , p. 1-10 10 p.

Specialized nutrition improves muscle function and physical activity without affecting chemotherapy efficacy in C26 tumour-bearing mice

Wijler Liza A, Raats Danielle A E, Elias Sjoerd G, Dijk Francina J, Quirindongo Hanil, May Anne M, Furber Matthew J W, Dorresteijn Bram, van Dijk Miriam, Kranenburg Onno 6 mei 2021, In: Journal of Cachexia, Sarcopenia and Muscle. 12 , p. 796-810 15 p.

Patient-derived organoids as a predictive biomarker for treatment response in cancer patients

Wensink G Emerens, Elias Sjoerd G, Mullenders Jasper, Koopman Miriam, Boj Sylvia F, Kranenburg Onno W, Roodhart Jeanine M L 12 apr 2021, In: NPJ precision oncology. 5

Development and Validation of Nomograms to Predict Local, Regional, and Distant Recurrence in Patients With Thin (T1) Melanomas

El Sharouni Mary Ann, Ahmed Tasnia, Varey Alexander H.R., Elias Sjoerd G., Witkamp Arjen J., Sigurdsson Vigfús, Suijkerbuijk Karijn P.M., van Diest Paul J., Scolyer Richard A., van Gils Carla H., Thompson John F., Blokx Willeke A.M., Lo Serigne N. 18 feb 2021, In: Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 39 , p. 1243-1252 10 p.

Prognostic factors for advanced colorectal neoplasia in inflammatory bowel disease:systematic review and meta-analysis

Wijnands Anouk M, de Jong Michiel E, Lutgens Maurice W M D, Hoentjen Frank, Elias Sjoerd G, Oldenburg Bas, 29 dec 2020, In: Gastroenterology. 160 , p. 1584-1598 15 p.

Mode of progression after radioembolization in patients with colorectal cancer liver metastases

van Roekel Caren, Jongen Jennifer M J, Smits Maarten L J, Elias Sjoerd G, Koopman Miriam, Kranenburg Onno, Borel Rinkes Inne H M, Lam Marnix G E H 22 sep 2020, In: EJNMMI Research. 10

All research output

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