Back

prof. dr. J.H.E. Kuball

Full Professor
prof. dr. J.H.E. Kuball
  • Laboratory for Translational Immunology (LTI)
  • Department of Medical Oncology

Biography

Biography

Prof. Dr. Jürgen Kuball received his medical degree as hematologists at the University of Mainz, Germany, and was further trained at the Fred Hutchinson Cancer Center in Seattle, WA, USA. Prof. Kuball joined the Department of Hematology at the University Medical Center in Utrecht in The Netherlands in 2007 as hematologists and immunologist. He became a VIDI-laureate in 2010 and chairs the section applied & tumor-immunology within the laboratory of translation immunology. Since 2013 he is chairing the Department of Hematology (adults). His clinical activities are focusing on treating patients with hematological malignancies including stem cell transplantation. His clinical-translational efforts and patient care are driven by his role as Director of the Bone Marrow Transplantation Program at the University Medical Center Utrecht, as well as active membership of the leukemia working party and stem cell working party of HOVON. His current laboratory activities are focusing on the understanding of innate immune cells and their receptors to recognize malignant cells and virally infected cells as well as the genetic engineering of a transplant.

Side Activities

Board activities

  • EBMT Chair Legal and Regulatory Affairs Committee
  • HOVON General board 
  • KWF adviesraad  
  • Wetenschappelijke raad KIKA 

Translational Valorisation

  •  Cofounder and shareholder of Gadeta      

Memberships

  • ASH
  • CIMT Regulatory Research Group
  • EBMT
  • EHA Member
  • HOVON Leukemia working party
  • HOVON SCT working party 

External positions

  • Scientific advisor, GADETA, 2018 → 2020
  • Scientific Advisory Board, JAZZ pharmaceuticals, 11 Sep 2016
  • Scientific cofounder and CSO, GADETA, 2015 → 2018
  • Shareholder, GADETA, 2015 → …
  • Grant Support, speaker and joint patent application, Miltenyi Biotec, 2015 → …
  • Grant and Scientific advisory board, Novartis, 2015 → …

Fellowship and Awards

American Association of Cancer Research-GlaxoSmithKline Scholar in Cancer Research Award (2001)
Stipendiat der Deutschen Krebshilfe (2005-2007)
Team Science recognition award of the „Society for Immunotherapy of Cancer“ to Jürgen Kuball and the University of Washington, USA (2010)
VIDI-Laureate ZonMW, The Netherlands (2010)
KWF project Transit (534.100 euro) (2014)

Research Output (172)

Efficient lentiviral transduction method to gene modify cord blood CD8<sup>+</sup> T cells for cancer therapy applications

Lo Presti Vania, Cornel Annelisa M., Plantinga Maud, Dünnebach Ester, Kuball Jurgen, Boelens Jaap Jan, Nierkens Stefan, van Til Niek P. 11 jun 2021, In: Molecular Therapy - Methods and Clinical Development. 21 , p. 357-368 12 p.

Allogeneic Stem Cell Transplantation Platforms With Ex Vivo and In Vivo Immune Manipulations:Count and Adjust

de Witte Moniek, Daenen Laura G M, van der Wagen Lotte, van Rhenen Anna, Raymakers Reiner, Westinga Kasper, Kuball Jürgen jun 2021, In: HemaSphere. 5 12 p.

Allogeneic hematopoietic cell transplantation with cord blood versus mismatched unrelated donor with post-transplant cyclophosphamide in acute myeloid leukemia

Dholaria Bhagirathbhai, Labopin Myriam, Sanz Jaime, Ruggeri Annalisa, Cornelissen Jan, Labussière-Wallet Hélène, Blaise Didier, Forcade Edouard, Chevallier Patrice, Grassi Anna, Zubarovskaya Ludmila, Kuball Jürgen, Ceballos Patrice, Ciceri Fabio, Baron Frederic, Savani Bipin N, Nagler Arnon, Mohty Mohamad 3 mei 2021, In: Journal of hematology & oncology. 14

Addition of lenalidomide to intensive treatment in younger and middle-aged adults with newly diagnosed AML:the HOVON-SAKK-132 trial

Löwenberg Bob, Pabst Thomas, Maertens Johan, Gradowska Patrycja, Biemond Bart J, Spertini Olivier, Vellenga Edo, Griskevicius Laimonas, Tick Lidwine W, Jongen-Lavrencic Mojca, van Marwijk Kooy Marinus, Vekemans Marie-Christiane, van der Velden Walter J F M, Beverloo Berna, Michaux Lucienne, Graux Carlos, Deeren Dries, de Weerdt Okke, van Esser Joost W J, Bargetzi Mario, Klein Saskia K, Gadisseur Alain, Westerweel Peter E, Veelken Hendrik, Gregor Michael, Silzle Tobias, van Lammeren-Venema Daniëlle, Moors Ine, Breems Dimitri A, Hoogendoorn Mels, Legdeur Marie-Cecile J C, Fischer Thomas, Kuball Juergen, Cornelissen Jan, Porkka Kimmo, Juliusson Gunnar, Meyer Peter, Höglund Martin, Gjertsen Bjorn T, Janssen Jeroen J W M, Huls Gerwin, Passweg Jakob, Cloos Jacqueline, Valk Peter J M, van Elssen Catharina H M J, Manz Markus G, Floisand Yngvar, Ossenkoppele Gert J 23 feb 2021, In: Blood Advances. 5 , p. 1110-1121 12 p.

Cell-density independent increased lymphocyte production and loss rates post-autologous HSCT

Baliu Piqué Mariona, van Hoeven Vera, Drylewicz Julia, van der Wagen Lotte E, Janssen Anke, Otto Sigrid A, van Zelm Menno C, de Boer Rob J, Kuball Jürgen Jhe, Borghans Jose Am, Tesselaar Kiki 4 feb 2021, In: eLife. 10 22 p.

Inferior Outcome of Addition of the Aminopeptidase Inhibitor Tosedostat to Standard Intensive Treatment for Elderly Patients with AML and High Risk MDS

Janssen Jeroen, Löwenberg Bob, Manz Markus, Bargetzi Mario, Biemond Bart, Borne Peter von dem, Breems Dimitri, Brouwer Rolf, Chalandon Yves, Deeren Dries, Efthymiou Anna, Gjertsen Bjørn-Tore, Graux Carlos, Gregor Michael, Heim Dominik, Hess Urs, Hoogendoorn Mels, Jaspers Aurelie, Jie Asiong, Jongen-Lavrencic Mojca, Klein Saskia, Klift Marjolein van der, Kuball Jürgen, Lammeren-Venema Danielle van, Legdeur Marie-Cecile, Loosdrecht Arjan van de, Maertens Johan, Kooy Marinus van Marwijk, Moors Ine, Nijziel Marten, Obbergh Florence van, Oosterveld Margriet, Pabst Thomas, Poel Marjolein van der, Sinnige Harm, Spertini Olivier, Terpstra Wim, Tick Lidwine, Velden Walter van der, Vekemans Marie-Christiane, Vellenga Edo, Weerdt Okke de, Westerweel Peter, Stüssi Georg, Norden Yvette van, Ossenkoppele Gert 2 feb 2021, In: Cancers. 13 11 p.

Defining the Role of Donor Lymphocyte Infusion in High-Risk Hematologic Malignancies

Schmid Christoph, Kuball Jürgen, Bug Gesine 12 jan 2021, In: Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 39 , p. 397-418 22 p.

αβ T-cell graft depletion for allogeneic HSCT in adults with hematological malignancies

De Witte Moniek A., Janssen Anke, Nijssen Klaartje, Karaiskaki Froso, Swanenberg Luuk, van Rhenen Anna, Admiraal Rick, van der Wagen Lotte, Minnema Monique C., Petersen Eefke, Raymakers Reinier A.P., Westinga Kasper, Straetemans Trudy, Halkes Constantijn J.M., Boelens Jaap Jan, Kuball Jurgen 12 jan 2021, In: Blood Advances. 5 , p. 240-249 10 p.

International Forum on Transfusion Practices in Haematopoietic Stem-Cell Transplantation:Summary

Solves Pilar, Lozano Miquel, Zhiburt Eugene, Anguita Velasco Javier, Maria Pérez-Corral Ana, Monsalvo-Saornil Silvia, Yamazaki Sho, Okazaki Hitoshi, Selleng Kathleen, Aurich Konstanze, Krüger William, Buser Andreas, Holbro Andreas, Infanti Laura, Stehle Gregor, Pierelli Luca, Matteocci Antonella, Rigacci Luigi, De Vooght Karen M.K., Kuball Jurgen H.E., Fielding Katherine L., Westerman David A., Wood Erica M., Cohn Claudia S., Johnson Andrew, Koh Mickey B.C., Qadir Dara, Cserti-Gazdewich Christine, Daguindau Etienne, Angelot-Delettre Fanny, Tiberghien Pierre, Wendel-Neto Silvano, Fachini Roberta Maria, Morton Suzy, Craddock Charles, Lumley Matthew, Antoniewicz-Papis Jolanta, Hałaburda Kazimierz, Łętowska Magdalena, Dunbar Nancy 2021, In: Vox Sanguinis. 116 , p. 609-612 4 p.

Editorial: gamma delta T Cells in Cancer:γδ T Cells in Cancer

Coffelt Seth B., Kabelitz Dieter, Silva-Santos Bruno, Kuball Jurgen, Born Willi, Bank Ilan 20 nov 2020, In: Frontiers in Immunology. 11 , p. 1-3

All research output

Thank you for your review!

Has this information helped you?

Please tell us why, so that we can improve our website.

Working at UMC Utrecht

Contact

Emergency?

Directions

Appointments

Practical

umcutrecht.nl maakt gebruik van cookies

Deze website maakt gebruik van cookies Deze website toont video’s van o.a. YouTube. Dergelijke partijen plaatsen cookies (third party cookies). Als u deze cookies niet wilt kunt u dat hier aangeven. Wij plaatsen zelf ook cookies om onze site te verbeteren.

Lees meer over het cookiebeleid

Akkoord Nee, liever niet