dr. A. (Arief) Lalmohamed

dr. A. (Arief) Lalmohamed

Research Staff Other
dr. A. (Arief) Lalmohamed
  • Clinical Pharmacy



Arief Lalmohamed (1986) obtained his Master of Science in Pharmacy in 2010 (cum laude) at Utrecht University. He was awarded a personal NWO Mosaic grant (€ 200,000) and completed his PhD in 2014 (cum laude) at the Division of Pharmacoepidemiology and Clinical Pharmacology at Utrecht University ('Complications of hip and knee replacement surgery: a pharmacoepidemiologic approach'), in close collaboration with the Medicines and Healthcare Products Regulatory Agency (MHRA, UK), Aarhus University (Denmark) and Oxford University (UK). During his PhD, Arief was trained as a clinical pharmacologist (University Medical Center Utrecht) and an epidemiologist (University Medical Center Utrecht & McGill University Canada). In 2017, he completed his training as a clinical pharmacist at the hospital pharmacy of University Medical Center Utrecht.

Since 2016, he is head of the Clinical Drug Trials department of Pharmacy (UMC Utrecht) and is responsible for clinical pharmacological and specialized pharmeutical input in yearly 300+ clinical drug trials. In 2021, he was appointed as associate professor of pharmacoepidemiology and supervises six PhD students. He is member of the Medical Ethical Research Committee (METC) and has reviewed over 100 clinical study protocols.

He has a keen interest in education and holds a teaching position at the School of Pharmacy (Utrecht University) since 2017. He is chair of the MSc Oncology course, has co-developed the interprofessional learning platform at UMC Utrecht / Utrecht University, holds a Basic Teaching Certificate (BKO) and is actively involved in several postgraduate courses. He was nominated for several teaching and best MSc Pharmacy course awards. 

His research is focused on clinical pharmacoepidemiology, in particular real world safety and efficacy of licensed drugs and drug repurposing (i.e., identifying novel therapeutic uses for licensed drugs) within the clinical fields of 'Infection and Immunity' and 'Cancer'. He is (co)author of >50 publications in international peer reviewed scientific journals. Examples include chemotherapy dose individualization in stem cell transplantations and safety / efficacy of drugs in immuno(oncological) diseases. 

Research Output (89)

Busulfan target exposure attainment in children undergoing allogeneic hematopoietic cell transplantation:a single day versus a multiday therapeutic drug monitoring regimen

Bognàr T Tim, Kingma J S Jurjen, Smeijsters E H Erin, van der Elst K C M Kim, de Kanter C T M Klaartje, Lindemans C A Caroline, Egberts A C G Toine, Bartelink I H Imke, Lalmohamed A Arief Jul 2023, In: Bone Marrow Transplantation. 58 , p. 762-768 7 p.

Klinische farmacologie van cytotoxische geneesmiddelen bij pasgeborenen en zuigelingen

Nijstad Laura, Lalmohamed Arief, Zwaan C.M., Huitema AD 2023, In: Nederlands Tijdschrift voor Oncologie. 20 , p. 17-24

Overestimation of the effect of (fos)aprepitant on intravenous dexamethasone pharmacokinetics requires adaptation of the guidelines for children with chemotherapy-induced nausea and vomiting

Nijstad A Laura, de Vos-Kerkhof Evelien, Enters-Weijnen Catherine F, van de Wetering Marianne D, Tissing Wim J E, Tibben Matthijs M, Rosing Hilde, Lalmohamed Arief, Huitema Alwin D R, Zwaan C Michel Dec 2022, In: Supportive Care in Cancer. 30 , p. 9991-9999 9 p.

A Population Pharmacokinetic Modelling Approach to Unravel the Complex Pharmacokinetics of Vincristine in Children

Nijstad A Laura, Chu Wan-Yu, de Vos-Kerkhof Evelien, Enters-Weijnen Catherine F, van de Velde Mirjam E, Kaspers Gertjan J L, Barnett Shelby, Veal Gareth J, Lalmohamed Arief, Zwaan C Michel, Huitema Alwin D R Oct 2022, In: Pharmaceutical Research. 39 , p. 2487-2495 9 p.

Systemic glucocorticoid use during ICU admission and symptoms of posttraumatic stress disorder in intensive care unit survivors

van Gelder Thomas G, Lalmohamed Arief, van Diem-Zaal Irene J, Egberts Toine C G, Slooter Arjen J C 13 May 2022, In: Intensive Care Medicine. 48 , p. 762-764 3 p.

Bacillus Calmette-Guérin vaccine to reduce healthcare worker absenteeism in COVID-19 pandemic, a randomized controlled trial

Doesschate Thijs Ten, van der Vaart Thomas W, Debisarun Priya A, Taks Esther, Moorlag Simone J C F M, Paternotte Nienke, Boersma Wim G, Kuiper Vincent P, Roukens Anna H E, Rijnders Bart J A, Voss Andreas, Veerman Karin M, Kerckhoffs Angele P M, Oever Jaap Ten, van Crevel Reinout, van Nieuwkoop Cees, Lalmohamed Arief, van de Wijgert Janneke H H M, Netea Mihai G, Bonten Marc J M, van Werkhoven Cornelis W 28 Apr 2022, In: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases. 28 , p. 1278-1285 8 p.

A simple extemporaneous oral suspension of aprepitant yields sufficient pharmacokinetic exposure in children

Nijstad A Laura, de Vos-Kerkhof Evelien, Enters-Weijnen Catherine F, van de Wetering Marianne D, Tissing Wim J E, Hanff Lidwien M, Lange Rogier, Tibben Matthijs M, Rosing Hilde, Lalmohamed Arief, Zwaan C Michel, Huitema Alwin D R 4 Apr 2022, In: Journal of Oncology Pharmacy Practice. 29 , p. 899-904 6 p.

Association Between the Magnitude of Intravenous Busulfan Exposure and Development of Hepatic Veno-Occlusive Disease in Children and Young Adults Undergoing Myeloablative Allogeneic Hematopoietic Cell Transplantation

Bognàr Tim, Bartelink Imke H, Egberts Toine C G, Rademaker Carin M A, Versluys A Birgitta, Slatter Mary A, Kletzel Morris, Nath Christa E, Cuvelier Geoffrey D E, Savic Rada M, Dvorak Christopher, Long-Boyle Janel R, Cowan Morton J, Bittencourt Henrique, Bredius Robbert G M, Güngör Tayfun, Shaw Peter J, Ansari Marc, Hassan Moustapha, Krajinovic Maja, Hempel Georg, Marktel Sarah, Chiesa Robert, Théoret Yves, Lund Troy, Orchard Paul J, Wynn Robert F, Boelens Jaap Jan, Lalmohamed Arief Apr 2022, In: Transplantation and Cellular Therapy. 28 , p. 196-202 7 p.

Monitoring of Adverse Drug Reaction-Related Parameters in Children, Youth, and Young Adults Prescribed Antipsychotic Drugs by General Practitioners

Minjon Lenneke, van den Ban Els, Bazelier Marloes T, Lalmohamed Arief, Egberts Toine C G, Heerdink Eibert R 7 Oct 2021, In: Journal of Child and Adolescent Psychopharmacology. 32 , p. 36-44 9 p.

Mortality, causes of death and influence of medication use in patients with systemic lupus erythematosus vs matched controls

Bultink Irene E.M., De Vries Frank, Van Vollenhoven Ronald F., Lalmohamed Arief 5 Jan 2021, In: Rheumatology (United Kingdom). 60 , p. 207-216 10 p.

All research output

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