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dr. J.H.W. (Jeanette) Leusen

Associate Professor

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Research Output (112)

Breast Milk Prefusion F Immunoglobulin G as a Correlate of Protection Against Respiratory Syncytial Virus Acute Respiratory Illness

Mazur Natalie I., Horsley Nicole M., Englund Janet A., Nederend Maaike, Magaret Amalia, Kumar Azad, Jacobino Shamir R., de Haan Cornelis A.M., Khatry Subarna K., LeClerq Steven C., Steinhoff Mark C., Tielsch James M., Katz Joanne, Graham Barney S., Bont Louis J., Leusen Jeanette H.W., Chu Helen Y. 10 aug 2018, In: Journal of Infectious Diseases. 219 , p. 59-67 9 p.

Neutrophils Kill Antibody-Opsonized Cancer Cells by Trogoptosis

Matlung Hanke L., Babes Liane, Zhao Xi Wen, van Houdt Michel, Treffers Louise W., van Rees Dieke J., Franke Katka, Schornagel Karin, Verkuijlen Paul, Janssen Hans, Halonen Pasi, Lieftink Cor, Beijersbergen Roderick L., Leusen Jeanette H.W., Boelens Jaap J., Kuhnle Ingrid, van der Werff Ten Bosch Jutte, Seeger Karl, Rutella Sergio, Pagliara Daria, Matozaki Takashi, Suzuki Eiji, Menke-van der Houven van Oordt Catharina Willemien, van Bruggen Robin, Roos Dirk, van Lier Rene A.W., Kuijpers Taco W., Kubes Paul, van den Berg Timo K. 26 jun 2018, In: Cell Reports. 23 , p. 3946-3959.e6

Effector mechanisms of IgA antibodies against CD20 include recruitment of myeloid cells for antibody-dependent cell-mediated cytotoxicity and complement-dependent cytotoxicity

Lohse Stefan, Loew Sebastian, Kretschmer Anna, Jansen J H Marco, Meyer Saskia, Ten Broeke Toine, Rösner Thies, Dechant Michael, Derer Stefanie, Klausz Katja, Kellner Christian, Schwanbeck Ralf, French Ruth R, Tipton Thomas R W, Cragg Mark S, Schewe Denis M, Peipp Matthias, Leusen Jeanette H W, Valerius Thomas mei 2018, In: British Journal of Haematology. 181 , p. 413-417

Reformatting palivizumab and motavizumab from IgG to human IgA impairs their efficacy against RSV infection in vitro and in vivo

Jacobino Shamir R., Nederend Maaike, Reijneveld J. Frederiek, Augustijn Daan, Jansen J. H.Marco, Meeldijk Jan, Reiding Karli R., Wuhrer Manfred, Coenjaerts Frank E.J., Hack C. Erik, Bont Louis J., Leusen Jeanette H.W. apr 2018, In: mAbs. 10 , p. 453-462 10 p.

FcαRI Dynamics Are Regulated by GSK-3 and PKCζ During Cytokine Mediated Inside-Out Signaling

Ten Broeke Toine, Honing Henk, Brandsma Arianne M., Jacobino Shamir, Bakema Jantine E., Kanters Deon, van der Linden Jan A.M., Bracke Madelon, Koenderman Leo, Leusen Jeanette H.W. 1 jan 2018, In: Frontiers in Immunology. 9 1 p.

Single nucleotide polymorphisms of the high affinity IgG receptor FcγRI reduce immune complex binding and downstream effector functions

Brandsma Arianne M., Ten Broeke Toine, Van Dueren Den Hollander Evelien, Caniels Thomas G., Kardol-Hoefnagel Tineke, Kuball Jürgen, Leusen Jeanette H.W. 16 aug 2017, In: Journal of Immunology. 199 , p. 2432-2439 8 p.

DC subset-specific induction of T cell responses upon antigen uptake via Fcγ receptors in vivo

Lehmann Christian H K, Baranska Anna, Heidkamp Gordon F, Heger Lukas, Neubert Kirsten, Lühr Jennifer J, Hoffmann Alana, Reimer Katharina C, Brückner Christin, Beck Simone, Seeling Michaela, Kießling Melissa, Soulat Didier, Krug Anne B, Ravetch Jeffrey V, Leusen Jeanette H W, Nimmerjahn Falk, Dudziak Diana 7 apr 2017, In: Journal of Experimental Medicine. 214 , p. 1509-1528 20 p.

Human amniotic fluid antibodies protect the neonate against respiratory syncytial virus infection

Jacobino Shamir R., Nederend Maaike, Hennus Marije, Houben Michiel L. , Ngwuta Joan O., Viveen Marco, Coenjaerts Frank E.J., Hack C. Erik, van Neerven R. J Joost, Graham Barney S., Bont Louis, Leusen Jeanette H W nov 2016, In: Journal of Allergy and Clinical Immunology. 138 , p. 1477–1480.e5

Clarifying the Confusion between Cytokine and Fc Receptor "Common Gamma Chain"

Brandsma Arianne M, Hogarth P Mark, Nimmerjahn Falk, Leusen Jeanette H W 16 aug 2016, In: Immunity. 45 , p. 225-226 2 p.

The Therapeutic CD38 Monoclonal Antibody Daratumumab Induces Programmed Cell Death via Fcγ Receptor-Mediated Cross-Linking

Overdijk Marije B, Jansen J H Marco, Nederend Maaike, Lammerts van Bueren Jeroen J, Groen Richard W J, Parren Paul W H I, Leusen Jeanette H W, Boross Peter 1 aug 2016, In: Journal of Immunology. 197 , p. 807-813 7 p.

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