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prof. dr. J.H.W. (Jeanette) Leusen

prof. dr. J.H.W. (Jeanette) Leusen

Full Professor

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Research Output (138)

Myeloid checkpoint blockade improves killing of T-acute lymphoblastic leukemia cells by an IgA2 variant of daratumumab

Baumann Niklas, Arndt Christian, Petersen Judith, Lustig Marta, Rösner Thies, Klausz Katja, Kellner Christian, Bultmann Miriam, Bastian Lorenz, Vogiatzi Fotini, Leusen Jeanette H W, Burger Renate, Schewe Denis M, Peipp Matthias, Valerius Thomas 16 Aug 2022, In: Frontiers in Immunology. 13

Targeting Myeloid Checkpoint Molecules in Combination With Antibody Therapy:A Novel Anti-Cancer Strategy With IgA Antibodies?

Chan Chilam, Lustig Marta, Baumann Niklas, Valerius Thomas, van Tetering Geert, Leusen Jeanette H W 5 Jul 2022, In: Frontiers in Immunology. 13 , p. 1-21

Fc gamma receptor is not required for in vivo processing of radio- and drug-conjugates of the dead tumor cell-targeting monoclonal antibody, APOMAB (R)

Staudacher Alexander H, Liapis Vasilios, Wittwer Nicole L, Tieu William, Lam Hiu Chun, Leusen Jeanette, Brown Michael P 11 May 2022, In: Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie. 151 , p. 1-10

Analysing the protection from respiratory tract infections and allergic diseases early in life by human milk components:the PRIMA birth cohort

van Stigt Arthur H., Oude Rengerink Katrien, Bloemenkamp Kitty W.M., de Waal Wouter, Prevaes Sabine M.P.J., Le Thuy My, van Wijk Femke, Nederend Maaike, Hellinga Anneke H., Lammers Christianne S., den Hartog Gerco, van Herwijnen Martijn J.C., Garssen Johan, Knippels Léon M.J., Verhagen Lilly M., de Theije Caroline G.M., Lopez-Rincon Alejandro, Leusen Jeanette H.W., Van't Land Belinda, Bont Louis, 14 Feb 2022, In: BMC Infectious Diseases. 22

Anti-C2 Antibody ARGX-117 Inhibits Complement in a Disease Model for Multifocal Motor Neuropathy

Budding Kevin, Johansen Lill Eva, Van de Walle Inge, Dijkxhoorn Kim, de Zeeuw Elisabeth, Bloemenkamp Lauri M., Bos Jeroen W., Jansen Marc D., Curial Chantall A.D., Silence Karen, de Haard Hans, Blanchetot Christophe, Van de Ven Liesbeth, Leusen Jeanette H.W., Pasterkamp R. Jeroen, van den Berg Leonard H., Hack C. Erik, Boross Peter, van der Pol W. Ludo 1 Jan 2022, In: Neurology® neuroimmunology & neuroinflammation. 9 , p. 1-11

Targeting the high affinity receptor, FcγRI, in autoimmune disease, neuropathy, and cancer

Holtrop Tosca, Budding Kevin, Brandsma Arianne M, Leusen Jeanette H W 2022, In: Immunotherapy Advances. 2

Comparing CAR and TCR engineered T cell performance as a function of tumor cell exposure

Wachsmann Tassilo L A, Wouters Anne K, Remst Dennis F G, Hagedoorn Renate S, Meeuwsen Miranda H, van Diest Eline, Leusen Jeanette, Kuball Jürgen, Falkenburg J H Frederik, Heemskerk Mirjam H M 2022, In: OncoImmunology. 11

Anti-GD2 IgA kills tumors by neutrophils without antibody-associated pain in the preclinical treatment of high-risk neuroblastoma

Evers Mitchell, Stip Marjolein, Keller Kaylee, Willemen Hanneke, Nederend Maaike, Jansen Marco, Chan Chilam, Budding Kevin, Nierkens Stefan, Valerius Thomas, Meyer-Wentrup Friederike, Eijkelkamp Niels, Leusen Jeanette 29 Oct 2021, In: Journal for ImmunoTherapy of Cancer. 9 , p. 1-14

The selection of variable regions affects effector mechanisms of IgA antibodies against CD20

Evers Mitchell, Rösner Thies, Duenkel Anna, Jansen J H Marco Marco, Baumann Niklas, Ten Broeke Toine, Nederend Maaike, Eichholz Klara, Klausz Katja, Reiding Karli, Schewe Denis M M, Kellner Christian, Peipp Matthias, Leusen Jeanette H W, Valerius Thomas 15 Sep 2021, In: Blood Advances. 5 , p. 3807-3820 14 p.

Novel oncolytic adenovirus expressing enhanced cross-hybrid IgGA Fc PD-L1 inhibitor activates multiple immune effector populations leading to enhanced tumor killing in vitro, in vivo and with patient-derived tumor organoids

Hamdan Firas, Ylösmäki Erkko, Chiaro Jacopo, Giannoula Yvonne, Long Maeve, Fusciello Manlio, Feola Sara, Martins Beatriz, Feodoroff Michaela, Antignani Gabriella, Russo Salvatore, Kari Otto, Lee Moon, Järvinen Petrus, Nisen Harry, Kreutzman Anna, Leusen Jeanette, Mustjoki Satu, McWilliams Thomas G, Grönholm Mikaela, Cerullo Vincenzo 6 Aug 2021, In: Journal for ImmunoTherapy of Cancer. 9

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