prof. dr. G. Pasterkamp
prof. dr. G. Pasterkamp
- Central Diagnostic Laboratory
Research Programs
Biography
Biography
Gerard Pasterkamp, MD, is professor Experimental Cardiology and quarter maker of the Circulatory Health Research Center, UMC Utrecht. His research interests are in the field of cardiovascular biology and more specifically innovation in biomarkers. His research interests are in the field of cardiovascular biology and innovation in biomarkers and drug targets. The research group houses the largest atherosclerotic plaque biobank worldwide: Athero Express including >4000 patients. This biobank has generated new insights into determinants of plaque destabilisation. The laboratory also invests in the excavation of genetic determinants of atherosclerotic plaque characteristics. He coordinates national and EU based consortia with the aim to unravel biomarkers and mechanisms of atherosclerotic disease. His translational profile is noted in the private public consortia he is involved in. He is supervising three public private grants that have been rewarded with the aim to develop novel biomarkers and imaging technology to detect cardiac ischemia and endothelial dysfunction. In 2018 he obtained a LeDucq grant together with Prof G Owens (Virginia University) on the role of smooth muscle cell plasticity in the atherosclerotic plaque.
Side Activities
Editorial scientific board ATVB, Cardiovascular research, Atherosclerosis, Eur J Cardiovascular Pharmacology
Board member of Dutch Atherosclerosis Society
Review board LS7 EU-ERC advanced grants and Finnish Academy of Sciences
Research Output (653)
Kavousi Maryam et al. 28 Sep 2023, In: Nature Genetics. 55 , p. 1651-1664 14 p.
Benavente Ernest Diez, Karnewar Santosh, Buono Michele, Mili Eloi, Hartman Robin J G, Kapteijn Daniek, Slenders Lotte, Daniels Mark, Aherrahrou Redouane, Reinberger Tobias, Mol Barend M, de Borst Gert J, de Kleijn Dominique P V, Prange Koen H M, Depuydt Marie A C, de Winther Menno P J, Kuiper Johan, Björkegren Johan L M, Erdmann Jeanette, Civelek Mete, Mokry Michal, Owens Gary K, Pasterkamp Gerard, den Ruijter Hester M 17 Aug 2023, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 43 , p. 1836-1850 15 p.
Buono Michele F, Benavente Ernest Diez, Daniels Mark, Mol Barend M, Mekke Joost M, de Borst Gert J, de Kleijn Dominique P V, van der Laan Sander W, Pasterkamp Gerard, Onland-Moret Charlotte, Mokry Michal, den Ruijter Hester M 5 Jul 2023, In: Biology of Sex Differences. 14 12 p.
Graham Sarah E, Clarke Shoa L, Wu Kuan-Han H, Kanoni Stavroula, Zajac Greg J M, Ramdas Shweta, Surakka Ida, Ntalla Ioanna, Vedantam Sailaja, Winkler Thomas W, Locke Adam E, Marouli Eirini, Hwang Mi Yeong, Han Sohee, Narita Akira, Choudhury Ananyo, Bentley Amy R, Ekoru Kenneth, Verma Anurag, Trivedi Bhavi, Martin Hilary C, Hunt Karen A, Hui Qin, Klarin Derek, Zhu Xiang, Thorleifsson Gudmar, Helgadottir Anna, Gudbjartsson Daniel F, Holm Hilma, Olafsson Isleifur, Akiyama Masato, Sakaue Saori, Terao Chikashi, Kanai Masahiro, Zhou Wei, Brumpton Ben M, Rasheed Humaira, Ruotsalainen Sanni E, Havulinna Aki S, van der Laan Sander W, van Setten Jessica, de Kleijn Dominique, de Borst Gert J, Asselbergs Folkert W, Kraaijeveld Adriaan O, Beulens Joline W J, Pasterkamp Gerard, Hoefer Imo E, van der Harst Pim, Holmes Michael V, 26 May 2023, In: Nature. 618 , p. E19-E20
Prapiadou Savvina, Živković Luka, Thorand Barbara, George Marc J, van der Laan Sander W, Malik Rainer, Herder Christian, Koenig Wolfgang, Ueland Thor, Kleveland Ola, Aukrust Pal, Gullestad Lars, Bernhagen Jürgen, Pasterkamp Gerard, Peters Annette, Hingorani Aroon D, Rosand Jonathan, Dichgans Martin, Anderson Christopher D, Georgakis Marios K 28 Mar 2023,
Song Yipei, Cisternino Francesco, Mekke Joost M, de Borst Gert J, de Kleijn Dominique P V, Pasterkamp Gerard, Vink Aryan, Glastonbury Craig A, van der Laan Sander W, Miller Clint L 15 Mar 2023, In: Scientific Reports. 13
Benavente Ernest Diez, Karnewar Santosh, Buono Michele, Mili Eloi, Hartman Robin J G, Kapteijn Daniek, Slenders Lotte, Daniels Mark, Aherrahrou Redouane, Reinberger Tobias, Mol Barend M, de Borst Gert J, de Kleijn Dominique P V, Prange Koen H M, Depuydt Marie A C, de Winther Menno P J, Kuiper Johan, Bj Rkegren Johan L M, Erdmann Jeanette, Civelek Mete, Mokry Michal, Owens Gary K, Pasterkamp Gerard, den Ruijter Hester M 9 Feb 2023,
Kanoni Stavroula et al. 27 Dec 2022, In: Genome Biology. 23 , p. 1-42
Karamanavi Elisavet, McVey David G, van der Laan Sander W, Stanczyk Paulina J, Morris Gavin E, Wang Yifan, Yang Wei, Chan Kenneth, Poston Robin N, Luo Jun, Zhou Xinmiao, Gong Peng, Jones Peter D, Cao Junjun, Kostogrys Renata B, Webb Tom R, Pasterkamp Gerard, Yu Haojie, Xiao Qingzhong, Greer Peter A, Stringer Emma J, Samani Nilesh J, Ye Shu 2 Dec 2022, In: Circulation research. 131 , p. 1004-1017 14 p.
Mokry Michal, Boltjes Arjan, Slenders Lotte, Bel-Bordes Gemma, Cui Kai, Brouwer Eli, Mekke Joost M., Depuydt Marie A. C., Timmerman Nathalie, Waissi Farahnaz, Verwer Maarten C., Turner Adam W., Khan Mohammad Daud, Hodonsky Chani J., Diez Benavente Ernest, Hartman Robin J. G., van den Dungen Noortje A. M., Lansu Nico, Nagyova Emilia, Prange Koen H. M., Kovacic Jason C., Björkegren Johan L. M., Pavlos Eleftherios, Andreakos Evangelos, Schunkert Heribert, Owens Gary K., Monaco Claudia, Finn Aloke V., Virmani Renu, Leeper Nicholas J., de Winther Menno P. J., Kuiper Johan, de Borst Gert J., Stroes Erik S. G., Civelek Mete, de Kleijn Dominique P. V., den Ruijter Hester M., Asselbergs Folkert W., van der Laan Sander W., Miller Clint L., Pasterkamp Gerard Dec 2022, In: Nature Cardiovascular Research. 1 , p. 1140-1155 16 p.