prof. dr. B.W. (Bas) Raaymakers

prof. dr. B.W. (Bas) Raaymakers

Full Professor
prof. dr. B.W. (Bas) Raaymakers
  • Experimental Clinical Physics Radiotherapy

Research Programs




Bas Raaymakers is working to improve cancer therapy by investigating, as well as developing, new high precision radiotherapy.
Together with prof Jan Lagendijk but also with industrial partners Elekta and Philips he designed and built a hybrid MRI accelerator to facilitate high precision, soft-tissue based image guidance for radiotherapy. This enables better radiotherapy via dose escalation while decreasing toxicity.
At the same time, the translation of this new technology to the clinic is pursued. For instance fast, on-line treatment planning, so that the patient is treated based on the latest state of the anatomy. This improves the current radiotherapy practice and at the same time is a requirement for smooth clinical introduction of the MRI accelerator.
Clinical work flow and procedures for different tumour sites are under investigation. Two major categories can be distinguished: The first is improving the existing radiotherapy patient treatments, so better conform the dose distribution to the tumour shape to minimise harm to the surroundings. The second is enabling radiotherapy as an alternative for surgery for patients currently not eligible for radiotherapy, e.g. highly mobile tumours in the kidney. The motion is too large to safely administer dose with conventional radiotherapy technology, with the on-line MRI guidance the motion uncertainty can be mitigated and radiation can be safely administered, offering a completely non-invasive treatment.

Side Activities


Member of International Advisory Committee of Physics in Medicine and Biology (unpaid)




Fellowship and Awards

VENI grant in 2003, Technical feasibility of the MRI accelerator

Research Output (217)

Experimental validation of multi-fraction online adaptations in magnetic resonance guided radiotherapy

van den Dobbelsteen Madelon, Hackett Sara L., van Asselen Bram, Oolbekkink Stijn, Wolthaus Jochem W.H., de Vries J. H.Wilfred, Raaymakers Bas W. Oct 2023, In: Physics and Imaging in Radiation Oncology. 28 7 p.

Gating and intrafraction drift correction on a 1.5 T MR-Linac:Clinical dosimetric benefits for upper abdominal tumors

Grimbergen Guus, Hackett Sara L, van Ommen Fasco, van Lier Astrid L H M W, Borman Pim T S, Meijers Lieke T C, de Groot-van Breugel Eline N, de Boer Johannes C J, Raaymakers Bas W, Intven Martijn P W, Meijer Gert J 30 Sep 2023, In: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 189

Integration of operator-validated contours in deformable image registration for dose accumulation in radiotherapy

Bosma Lando S, Ries Mario, Denis de Senneville Baudouin, Raaymakers Bas W, Zachiu Cornel Jul 2023, In: Physics and Imaging in Radiation Oncology. 27 7 p.

Feasibility of online radial magnetic resonance imaging for adaptive radiotherapy of pancreatic tumors

Grimbergen Guus, Eijkelenkamp Hidde, van Vulpen Jonna K, van de Ven Saskia, Raaymakers Bas W, Intven Martijn P W, Meijer Gert J Apr 2023, In: Physics and Imaging in Radiation Oncology. 26 , p. 1-6

Technical Note:Intensity-based quality assurance criteria for deformable image registration in image-guided radiotherapy

Bosma L S, Zachiu C, de Senneville B Denis, Raaymakers B W, Ries M 18 Mar 2023, In: Medical Physics. 50 , p. 5715-5722 8 p.

Performance of the HYPERSCINT scintillation dosimetry research platform for the 1.5 T MR-linac

Uijtewaal Prescilla, Côté Benjamin, Foppen Thomas, de Vries Wilfred, Woodings Simon, Borman Pim, Lambert-Girard Simon, Therriault-Proulx François, Raaymakers Bas, Fast Martin 21 Feb 2023, In: Physics in medicine and biology. 68 , p. 1-11

Feasibility of delivered dose reconstruction for MR-guided SBRT of pancreatic tumors with fast, real-time 3D cine MRI

Grimbergen Guus, Pötgens Giulia G., Eijkelenkamp Hidde, Raaymakers Bas W., Intven Martijn P.W., Meijer Gert J. 2 Feb 2023, In: Radiotherapy and Oncology. 182

ESTRO Breur lecture 2022:Real-time MRI-guided radiotherapy: The next generation standard?

Lagendijk Jan J W, Raaymakers Bas W, Intven Martijn P W, van der Voort van Zyp Jochem R N Nov 2022, In: Radiotherapy & Oncology. 176 , p. 244-248 5 p.

Dosimetric evaluation of off-axis fields and angular transmission for the 1.5 T MR-linac

van den Dobbelsteen M., Hackett S. L., de Vries J. H.W., van Asselen B., Oolbekkink S., Woodings S. J., Raaymakers B. W. 21 Oct 2022, In: Physics in medicine and biology. 67

Robust deep learning-based forward dose calculations for VMAT on the 1.5T MR-Linac

Tsekas Georgios, Bol Gijsbert H, Raaymakers Bas W 5 Oct 2022, In: Physics in medicine and biology. 67 , p. 1-8

All research output

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