dr. ir. E. (Ewoud) Schuit

dr. ir. E. (Ewoud) Schuit

Assistant Professor
dr. ir. E. (Ewoud) Schuit
  • Department of Epidemiology
  • Julius Center Research Program Methodology



Currently I mainly focus on the evaluation of healthcare innovations, but also the innovation of evaluation of healthcare innovations. I do this as a core member of The Healthcare Innovation Center (THINC., a center that is part of the Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, and that aims to assess the efficacy, usability, cost-effectiveness, and impact after implementation of healthcare innovations, therby enabling to fasttrack promising innovations and to halt innovativons that may not be that useful afterall.

My other scientific work on the one hand includes empirical studies aimed at enhancing personalized management, mainly by using (network) meta-analysis and prognostic modeling. I have conducted and am involved in several large international individual participant data (IPD) meta-analyses in the focus is generally on subgroup effects, and I've reviewed, developed and validated numerous clinical prediction models. On the other hand my work focuses on methodology for prediction research and IPD (network) meta-analysis, with again a focus on subgroup analysis to identify individuals that may benefit from treatment more than others. Additionally I serve as a methodologist/consultant in the Dutch Consortium for Healthcare Evaluation and Research in Obstetrics and Gynaecology (

Research Output (141)

When is it impractical to ask informed consent?:A systematic review

Laurijssen Sara Jm, van der Graaf Rieke, van Dijk Wouter B, Schuit Ewoud, Groenwold Rolf Hh, Grobbee Diederick E, de Vries Martine C 1 Jul 2022, In: Clinical Trials. 19 , p. 545-560 16 p.

2,109 randomized oncology trials map continuous, meager improvements in progression-free and overall survival over 50 years

Parish Austin J, Alina-Cristea Ioana, Schuit Ewoud, Ioannidis John P A 28 Jun 2022, In: Journal of Clinical Epidemiology. 150 , p. 106-115 10 p.

Model-Based Selection for Proton Therapy in Breast Cancer:Development of the National Indication Protocol for Proton Therapy and First Clinical Experiences

Boersma L J, Sattler M G A, Maduro J H, Bijker N, Essers M, van Gestel C M J, Klaver Y L B, Petoukhova A L, Rodrigues M F, Russell N S, van der Schaaf A, Verhoeven K, van Vulpen M, Schuit E, Langendijk J A Apr 2022, In: Clinical Oncology. 34 , p. 247-257 11 p.

Genetically Determined Reproductive Aging and Coronary Heart Disease: A Bidirectional 2-sample Mendelian Randomization:A Bidirectional 2-sample Mendelian Randomization

Dam Veerle, Onland-Moret N Charlotte, Burgess Stephen, Chirlaque Maria-Dolores, Peters Sanne A E, Schuit Ewoud, Tikk Kaja, Weiderpass Elisabete, Oliver-Williams Clare, Wood Angela M, Tjønneland Anne, Dahm Christina C, Overvad Kim, Boutron-Ruault Marie-Christine, Schulze Matthias B, Trichopoulou Antonia, Ferrari Pietro, Masala Giovanna, Krogh Vittorio, Tumino Rosario, Matullo Giuseppe, Panico Salvatore, Boer Jolanda M A, Verschuren W M Monique, Waaseth Marit, Sánchez Pérez Maria José, Amiano Pilar, Imaz Liher, Moreno-Iribas Conchi, Melander Olle, Harlid Sophia, Nordendahl Maria, Wennberg Patrik, Key Timothy J, Riboli Elio, Santiuste Carmen, Kaaks Rudolf, Katzke Verena, Langenberg Claudia, Wareham Nicholas J, Schunkert Heribert, Erdmann Jeanette, Willenborg Christina, Hengstenberg Christian, Kleber Marcus E, Delgado Graciela, März Winfried, Kanoni Stavroula, Dedoussis George, Deloukas Panos, Nikpay Majid, McPherson Ruth, Scholz Markus, Teren Andrej, Butterworth Adam S, van der Schouw Yvonne T 20 Mar 2022, In: The Journal of clinical endocrinology and metabolism. 107 , p. e2952-e2961 10 p.

Krankenhauskosten und gesundheitsbezogene Lebensqualität bei Patienten mit Delir:ein Scoping-Review

van Lieshout Chris, Schuit Ewoud, Hermes Carsten, Kerrigan Matthew, Frederix Geert W J 11 Mar 2022, In: Zeitschrift fur Evidenz, Fortbildung und Qualitat im Gesundheitswesen. 169 , p. 28-38 11 p.

Detection of SARS-CoV-2 infection in the general population by three prevailing rapid antigen tests:cross-sectional diagnostic accuracy study

Venekamp Roderick P, Veldhuijzen Irene K, Moons Karel G M, van den Bijllaardt Wouter, Pas Suzan D, Lodder Esther B, Molenkamp Richard, Igloi Zsofi, Wijers Constantijn, Dos Santos Claudy Oliveira, Debast Sylvia B, Bruins Marjan J, Polad Khaled, Nagel-Imming Carla R S, Han Wanda G H, van de Wijgert Janneke H H M, van den Hof Susan, Schuit Ewoud 24 Feb 2022, In: BMC Medicine. 20

Performance of binary prediction models in high-correlation low-dimensional settings:a comparison of methods

Leeuwenberg Artuur M, van Smeden Maarten, Langendijk Johannes A, van der Schaaf Arjen, Mauer Murielle E, Moons Karel G M, Reitsma Johannes B, Schuit Ewoud 11 Jan 2022, In: Diagnostic and Prognostic Research. 6

Guidelines and quality criteria for artificial intelligence-based prediction models in healthcare:a scoping review

de Hond Anne A.H., Leeuwenberg Artuur M., Hooft Lotty, Kant Ilse M.J., Nijman Steven W.J., van Os Hendrikus J.A., Aardoom Jiska J., Debray Thomas P.A., Schuit Ewoud, van Smeden Maarten, Reitsma Johannes B., Steyerberg Ewout W., Chavannes Niels H., Moons Karel G.M. 10 Jan 2022, In: NPJ DIGITAL MEDICINE. 5

Accuracy of approximations to recover incompletely reported logistic regression models depended on other available information

Takada Toshihiko, Hoogland Jeroen, van Lieshout Chris, Schuit Ewoud, Collins Gary S, Moons Karel G M, Reitsma Johannes B 1 Dec 2021, In: Journal of Clinical Epidemiology. 143 , p. 81-90 10 p.

Added Value of Cognition in the Prediction of Survival in Low and High Grade Glioma

van Kessel Emma, Schuit Ewoud, Huenges Wajer Irene M C, Ruis Carla, De Vos Filip Y F L, Verhoeff Joost J C, Seute Tatjana, van Zandvoort Martine J E, Robe Pierre A, Snijders Tom J 18 Nov 2021, In: Frontiers in Neurology. 12 , p. 1-11

All research output

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