prof. dr. H.B. (Bart) van der Worp

prof. dr. H.B. (Bart) van der Worp

Full Professor
prof. dr. H.B. (Bart) van der Worp
  • Neurologen

Research Programs



Bart van der Worp is a neurologist with a special interest in cerebrovascular diseases at the University Medical Center in Utrecht, the Netherlands. He has been (co-)Chief Investigator of the randomised stroke trials HAMLET, PAIS, COOLIST, VAST, APACHE-AF, and MR ASAP and is Chief Investigator of PRECIOUS. He is a member of the Dutch CONTRAST consortium which aims to identify and test new treatments for patients with acute ischaemic stroke or intracerebral haemorrhage. He is former President of the European Stroke Organisation.

Side Activities

2008 –          fellow of the European Stroke Organisation (ESO)

2011 – 2022 member of the Board of Directors of ESO

2011 – 2016 member of the Committee for Professional Interests (BBC) of the NVN

2013 – 2015 member of the Committee for Clinical trials of ESO

2013 – 2017 member of the Guideline Committee of ESO

2014 – 2016 vice-president ESO

2014 – 2021 member of the writing committee of the Dutch Stroke Guideline

2016 – 2018 president-elect ESO

2018 – 2020 president ESO

2019 – 2021 member of Committee on emergency prehospital care (45-minutennorm) of the Gezondheidsraad

2019 - 2020 consultant, Bayer

2020 – 2022 past president ESO

2020 – 2021 Chair module writing group ESO guideline on space-occupying oedema

2022 -          consultant, TargED

2022 -          national coordinator randomised trial, Bayer


Member of Data and Safety Monitoring Boards of randomised trials

2005 – 2007 Randomized sequential trial of valproic acid in amyotrophic lateral sclerosis

2009 – 2011 Intrathecal methylprednisolone for intractable postherpetic neuralgia: STIP study. (Steroids for Intractable Postherpetic Neuralgia)

2009 – 2011 A randomised sequential trial of Lithium In amyotrophic lateral sclerosis

2015 – 2021 TELSTAR: Treatment of electroencephalographic status epilepticus after cardiopulmonary resuscitation - a randomized controlled trial (Chair)

2018 – 2019 PHALS: A placebo-controlled double blind randomized trial to investigate the efficacy and safety of the combination of Penicillin G / Hydrocortisone treatment in ALS patients (Chair)

2018 –          RESSTORE: Regenerative Stem Cell Therapy for Stroke in Europe

2019 –          GRECO: Ghrelin treatment of comatose patients after cardiac arrest: A phase 2 clinical trial to estimate safety and efficacy of ghrelin to promote cerebral (Chair)

Research Output (226)

Effects of oral anticoagulation in people with atrial fibrillation after spontaneous intracranial haemorrhage (COCROACH):prospective, individual participant data meta-analysis of randomised trials

Al-Shahi Salman Rustam, Stephen Jacqueline, Tierney Jayne F., Lewis Steff C., Newby David E., Parry-Jones Adrian R., White Philip M., Connolly Stuart J., Benavente Oscar R., Dowlatshahi Dar, Cordonnier Charlotte, Viscoli Catherine M., Sheth Kevin N., Kamel Hooman, Veltkamp Roland, Larsen Kristin T., Hofmeijer Jeannette, Kerkhoff Henk, Schreuder Floris H.B.M., Shoamanesh Ashkan, Klijn Catharina J.M., van der Worp H. Bart, Klug Didier, Casolla Barbara, Puy Laurent, Coffee Morgane, Kuchcinski Grégory, Labreuche Julien, van Nieuwenhuizen Koen M., Algra Ale, van Gelder Isabelle C., Kappelle L. Jaap, Rinkel Gabriel J.E., Schutgens Roger E.G., Khatri Pooja, Conwit Robin, Falcone Guido, Elm Jordan, Anderson Craig S., Song Lili, Pandian Jeyaraj, Hart Robert G., Sharma Mukul, Aref Hany, Tarhuni Wadea, Fabregas Joan Marti, Diener Hans Christoph, Endres Matthias, Lemmens Robin, Kwon Sun U., Dec 2023, In: The Lancet Neurology. 22 , p. 1140-1149 10 p.

Continuous Theta-Burst Stimulation of the Contralesional Primary Motor Cortex for Promotion of Upper Limb Recovery After Stroke:A Randomized Controlled Trial

Vink Jord J.T., van Lieshout Eline C.C., Otte Willem M., van Eijk Ruben P.A., Kouwenhoven Mirjam, Neggers Sebastiaan F.W., van der Worp H. Bart, Visser-Meily Johanna M.A., Dijkhuizen Rick M. 1 Aug 2023, In: Stroke. 54 , p. 1962-1971 10 p.

Antithrombotic Treatment in Patients With Hemophilia:an EHA-ISTH-EAHAD-ESO Clinical Practice Guidance

Schutgens Roger E.G., Jimenez-Yuste Victor, Escobar Miguel, Falanga Anna, Gigante Bruna, Klamroth Robert, Lassila Riitta, Leebeek Frank W.G., Makris Michael, Owaidah Tarek, Sholzberg Michelle, Tiede Andreas, Werring David J., Van Der Worp H. Bart, Windyga Jerzy, Castaman Giancarlo 5 Jun 2023, In: Hemasphere. 7 , p. 1-21

Prognostic Value of Thrombus Volume and Interaction With First-Line Endovascular Treatment Device Choice

Van Voorst Henk et al. 1 Apr 2023, In: Stroke. 54 , p. 1056-1065 10 p.

Assessment of aortic and cerebral haemodynamics and vascular brain injury with 3 and 7 T magnetic resonance imaging in patients with aortic coarctation

Meijs Timion A., Van Tuijl Rick J., Van Den Brink Hilde, Weaver Nick A., Siero Jeroen C.W., Van Der Worp H. Bart, Braun Kees P.J., Leiner Tim, De Jong Pim A., Zwanenburg Jaco J.M., Doevendans Pieter A., Voskuil Michiel, Grotenhuis Heynric B. 11 Jan 2023, In: European heart journal open. 3 10 p.

Sexual dimorphism in peripheral blood cell characteristics linked to recanalization success of endovascular thrombectomy in acute ischemic stroke

Overmars L Malin, van Solinge Wouter W, Ruijter Hester M den, van der Worp H Bart, Van Es Bram, Hulsbergen-Veelken Cornelia A R, Biessels Geert Jan, Exalto Lieza G, Haitjema Saskia 2023, In: Journal of thrombosis and thrombolysis. 56 , p. 614-625 12 p.

Prehospital transdermal glyceryl trinitrate in patients with presumed acute stroke (MR ASAP):an ambulance-based, multicentre, randomised, open-label, blinded endpoint, phase 3 trial

van den Berg Sophie A, Uniken Venema Simone M, Reinink Hendrik, Hofmeijer Jeannette, Schonewille Wouter J, Miedema Irene, Fransen Puck S S, O Pruissen D Martijn, Raaijmakers Theodora W M, van Dijk Gert W, de Leeuw Frank-Erik, van Vliet Jorine A, Kwa Vincent I H, Kerkhoff Henk, van 't Net Alex, Boomars Rene, Siegers Arjen, Lok Tycho, Caminada Klaartje, Esteve Cuevas Laura M, Visser Marieke C, Zwetsloot Casper P, Boomsma Jooske M F, Schipper Mirjam H, van Eijkelenburg Roeland P J, Berkhemer Olvert A, Nieboer Daan, Lingsma Hester F, Emmer Bart J, van Oostenbrugge Robert J, van der Lugt Aad, Roos Yvo B W E M, Majoie Charles B L M, Dippel Diederik W J, Nederkoorn Paul J, van der Worp H Bart, Nov 2022, In: The Lancet. Neurology. 21 , p. 971-981 11 p.

Time Since Stroke Onset, Quantitative Collateral Score, and Functional Outcome After Endovascular Treatment for Acute Ischemic Stroke

Uniken Venema Simone M, Wolff Lennard, van den Berg Sophie A, Reinink Hendrik, Luijten Sven P R, Lingsma Hester F, Marquering Henk A, Boers Anna M M, Bot Joost, Hammer Sebastiaan, Nederkoorn Paul J, Roos Yvo B W E M, Majoie Charles B L M, Dankbaar Jan Willem, van der Lugt Aad, van der Worp H Bart, 11 Oct 2022, In: Neurology. 99 , p. e1609-e1618

Cerebral Collateral Circulation in the Era of Reperfusion Therapies for Acute Ischemic Stroke

Uniken Venema Simone M, Dankbaar Jan Willem, van der Lugt Aad, Dippel Diederik W J, van der Worp H Bart Oct 2022, In: Stroke. 53 , p. 3222-3234 13 p.

All research output

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