prof. dr. R. (Richard) van Hillegersberg

prof. dr. R. (Richard) van Hillegersberg

Full Professor
prof. dr. R. (Richard) van Hillegersberg
  • Department of Surgical Oncology

Research Programs

Strategic Program Cancer



Richard van Hillegersberg attended medical school in Rotterdam, the Netherlands. In 1993 he received his PhD with honor at the Department of Surgery, Erasmus MC in Rotterdam. From 1994-2000, he was trained in General Surgery in Rotterdam. From 2001-2002 he was fellow of Surgical Oncology in the Academic Medical Center and Antoni van Leeuwenhoek Netherlands Cancer Center Amsterdam. Since 2003 he is appointed as staff surgeon at the University Medical Center Utrecht. From 2009 he is a full professor of gastrointestinal oncology. Research is focused on Upper GI minimally invasive and robotic surgery, surgical imaging and genetic profiling. He has authored over 15 chapters in textbooks concerning robotic forgut surgery and over 500 articles in international peer-reviewed journals. From 2018 he is chairman of the Educational committee of the European Society for Diseases for the Esophagus (ESDE) and member of the education committee of ISDE, he is associate editor of Diseases of the Esophagus and Digestive Surgery, founder and chairman of the Upper GI International Robotic Association (UGIRA).

Side Activities

Member board and educational committee Europen Society Diseases of the Esophagus (ESDE)

Member Council European Digestive Surgery

Member Scientific Committee United European Gastroenterology (UEG)

Member Committee Dutch Guidelines oesophageal cancer

Member board Dutch UpperGI Cancer Audit (DUCA)

Associate editor Digestive Surgery

Associate editor Diseases of the Esophagus

Proctor Upper GI robotic Surgery Intuitive Surgical (paid)

Fellowship and Awards

2014-present. Principle investigator. Cost effectiveness of laparoscopic gastrectomy  as an alternative to open gastrectomy for gastric cancer (LOGICA trial). NCT02248519. ZonMw (837002502) Eu 400.000

2014-present. Principle investigator. Esophagectomy for Patients With Esophageal Cancer and Cervical Lymph Node Metastases (NODE trial). NCT02426879

2017-present. Intuitive Clinical Research Grant for the project “The International Registry for Robot-assisteted Minimally Invasive Esophagectomy” (RAMIE). Unrestricted Grant $ 50.000

2017-present. International Database collaboration Robotic esophagectomy, Intuitive Surgical, Unrestricted Grant. Eu 50.000

 2017-present. Coordinating Investigator of International Centers. Surgery for adenocarcinoma of the gastroesophageal junction (GEJ) type II: transthoracic esophagectomy vs. transhiatal extended gastrectomy (CARDIA trial). Analyzing in a multicenter international setting the optimal surgical strategy for tumors at the oesophago-gastric junction. This trial is now recruiting in collaboration with The University of Koln. Deutsches Register Klinischer Studien. DRKS-number: 00016923. Federal Ministry for Education and Research. Bundesministerium für Bildung und Forschung (BMBF) (grant number 01KG1816). Eu 1.940.000

2018-present. G.J.Meijer. Preoperative Image-guided Identification of Response to Neoadjuvant Chemoradiotherapy in Esophageal Cancer (PRIDE). NCT03474341. KWF (10291) Eu 890.260

2020-present Principal investigator. Paravertabral catheter versus epidural anagesia in minimally invasive esophageal resection : a RCT (PEPMEN trail). ZonMw (852002004) Eu 392.650

Research Output (506)

Hospital Variation in Feeding Jejunostomy Policy for Minimally Invasive Esophagectomy:A Nationwide Cohort Study

Visser Maurits R, Straatman Jennifer, Voeten Daan M, Gisbertz Suzanne S, Ruurda Jelle P, Luyer Misha D P, van der Sluis Pieter C, van der Peet Donald L, van Berge Henegouwen Mark I, van Hillegersberg Richard, Jan 2023, In: Nutrients. 15

Identifying a core symptom set triggering radiological and endoscopic investigations for suspected recurrent esophago-gastric cancer:a modified Delphi consensus process

Chidambaram Swathikan, Patel Nikhil M., Sounderajah Viknesh, Alfieri Rita, Bonavina Luigi, Cheong Edward, Cockbain Andy, D'Journo Xavier Benoit, Ferri Lorenzo, Griffiths Ewen A., Grimminger Peter, Gronnier Caroline, Gutschow Christian, Hedberg Jakob, Kauppila Joonas H., Lagarde Sjoerd, Low Donald, Nafteux Philippe, Nieuwenhuijzen Grard, Nilsson Magnus, Rosati Riccardo, Schroeder Wolfgang, Smithers B. Mark, van Berge Henegouwen Mark I., van Hillegesberg Richard, Watson David I., Vohra Ravinder, Maynard Nick, Markar Sheraz R. 31 Dec 2022, In: Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus. 36

Cost-effectiveness of Laparoscopic vs Open Gastrectomy for Gastric Cancer:An Economic Evaluation Alongside a Randomized Clinical Trial

van der Veen Arjen, van der Meulen Miriam P, Seesing Maarten F J, Brenkman Hylke J F, Haverkamp Leonie, Luyer Misha D P, Nieuwenhuijzen Grard A P, Stoot Jan H M B, Tegels Juul J W, Wijnhoven Bas P L, Lagarde Sjoerd M, de Steur Wobbe O, Hartgrink Henk H, Kouwenhoven Ewout A, Wassenaar Eelco B, Draaisma Werner A, Gisbertz Suzanne S, van der Peet Donald L, van Laarhoven Hanneke W M, Frederix Geert W J, Ruurda Jelle P, van Hillegersberg Richard, 28 Dec 2022, In: JAMA Surgery. 158 , p. 120-128 9 p.

Liver oligometastatic disease in synchronous metastatic gastric cancer patients:a nationwide population-based cohort study

Kroese Tiuri E, Takahashi Yuko, Lordick Florian, van Rossum Peter S N, Ruurda Jelle P, Lagarde Sjoerd M, van Hillegersberg Richard, Verhoeven Rob H A, van Laarhoven Hanneke W M 15 Nov 2022, In: European Journal of Cancer. 179 , p. 65-75 11 p.

Stereotactic radiotherapy or metastasectomy for oligometastatic esophagogastric cancer:A nationwide population-based cohort study

Kroese Tiuri E, Jorritsma Nikita K N, van Laarhoven Hanneke W M, Verhoeven Rob H A, Mook Stella, Haj Mohammad Nadia, Ruurda Jelle P, van Rossum Peter S N, van Hillegersberg Richard Nov 2022, In: Clinical and translational radiation oncology. 37 , p. 109-115 7 p.

Physical functioning and physical activity after gastrointestinal or bladder oncological surgery:An observational cohort study

Bor Petra, de Leeuwerk Marijke Elizabeth, Valkenet Karin, van Hillegersberg Richard, Veenhof Cindy Nov 2022, In: European Journal of Cancer Care. 31 , p. 1-8

Team dynamics and clinician's experience influence decision-making during Upper-GI multidisciplinary team meetings:A multiple case study

Luijten J C H B M, Westerman M J, Nieuwenhuijzen G A P, Walraven J E W, Sosef M N, Beerepoot L V, van Hillegersberg R, Muller K, Hoekstra R, Bergman J J G H M, Siersema P D, van Laarhoven H W M, Rosman C, Brom L, Vissers P A J, Verhoeven R H A Oct 2022, In: Frontiers in oncology. 12 , p. 1-12

Pattern of lymph node metastases in gastric cancer:a side-study of the multicenter LOGICA-trial

de Jongh Cas, Triemstra Lianne, van der Veen Arjen, Brosens Lodewijk A A, Luyer Misha D P, Stoot Jan H M B, Ruurda Jelle P, van Hillegersberg Richard, 14 Sep 2022, In: Gastric Cancer. 25 , p. 1060-1072 13 p.

The influence of anastomotic techniques on postoperative anastomotic complications:Results of the Oesophago-Gastric Anastomosis Audit

Kamarajah S. K., Evans R. P.T., Nepogodiev D., Hodson J., Bundred J., Gockel I., Gossage J. A., Isik A., Kidane B., Mahendran H. A., Negoi I., Okonta K. E., Sayyed R. H., van Hillegersberg R., Vohra R., Wijnhoven B. P.L., Singh P., Griffiths E. A., Kamarajah S. K., Hodson J., Griffiths E. A., Alderson D., Bundred J., Evans R. P.T., Gossage J., Griffiths E. A., Jefferies B., Kamarajah S. K., McKay S., Mohamed I., Nepogodiev D., Siaw-Acheampong K., Singh P., van Hillegersberg R., Vohra R., van Hillegersberg R., Read M., Tan J. H., Matthijsen R., Ruurda J. P., van der Sluis P. C., de Maat M., Martínez E. T., Yildirim R., Wong V., Cox M., Mehta S., Kumar S., Athanasiou A., Singh A., Sep 2022, In: Journal of Thoracic and Cardiovascular Surgery. 164 , p. 674-684.e5

Computer-aided anatomy recognition in intrathoracic and -abdominal surgery:a systematic review

den Boer R B, de Jongh C, Huijbers W T E, Jaspers T J M, Pluim J P W, van Hillegersberg R, Van Eijnatten M, Ruurda J P 4 Aug 2022, In: Surgical endoscopy. 36 , p. 8737-8752 16 p.

All research output

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