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dr. G.J.T. Zwartkruis

dr. G.J.T. Zwartkruis

Associate Professor

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Research Output (55)

Insulin acativation of Rheb, a mediator of mTOR/S6K/4E-BP signaling is inhibited by TSC1 and 2

Garami A., Zwartkruis G.J.T., Nobukuni T., Joaquin M., Roccio M., Stocker H., Kozma S.C., Hafen E., Bos J.L., Thomas G. 2003, In: Molecular Cell. 11 , p. 1457-1466 10 p.

The small GTPase Rap1 is activated by turbulence and is involved in integrin alphaIIb ß3-mediated cell adhesion in human megakaryocytes

de Bruyn K.M.T., Zwartkruis G.J.T., de Rooij Johan, Akkerman J.W.N., Bos J.L. 2003, In: Journal of Biological Chemistry. 278 , p. 22412-22417 6 p.

Characterisation of PDZ-GEFs, a family of guanine nucleotide exchange factors specific for Rap1 and Rap2

Kuiperij H.B., de Rooij J., Rehmann H., van Triest M., Wittinghofer A., Bos J.L., Zwartkruis G.J.T. 2003, In: Biochimica et Biophysica Acta-Molecular Cell Research. 1593 , p. 141-149 9 p.

The role of Rap1 in integrin-mediated cell adhesion

Bos J.L., de Bruyn K.M.T., Enserink J.M., Kuiperij H.B., Rangarajan S., Rehmann H., Riedl J.A., de Rooij J., van Mansfeld A.D.M., Zwartkruis G.J.T. 2003, In: Biochemical Society Transactions. 31 , p. 83-86 4 p.

Activation of the small G Protein Rap 1 in dog thyroid cells by both cAMP-dependent and -independent pathways

Dremier S., Vandeput F., Zwartkruis G.J.T., Bos J.L., Dumont J.E., Maenhaut C. 2000, In: Biochemical and Biophysical Research Communications. 267 , p. 7-11 5 p.

The small GTPases Rap1 mediates CD31-induced integrin adhesion

Reequist K.A., Ross E., Koop E.A., Wolthuis R.M.F., Zwartkruis G.J.T., van Kooyk Y., Salmon M., Buckley C.D., Bos J.L. 2000, In: Journal of Cell Biology. 148 , p. 1151-1158 8 p.

Differential fMetLeuPhe- and PAF-induced signaling toward Ral activation in primary human neutrophils

M'Rabet L., Coffer P.J, Wolthuis R.M.F., Zwartkruis G.J.T., Koenderman L., Bos J.L. 1999, In: Journal of Biological Chemistry. 274 , p. 21847-21852 6 p.

Ras and Rap1: Two highly related small GTPases with distinct function

Zwartkruis G.J.T., Bos J.L. 1999, In: Experimental Cell Research. 253 , p. 157-165 9 p.

Signal Transduction: Rapsody in G proteins

Bos J.L., Zwartkruis G.J.T. 1999, In: Nature. 400 , p. 820-821 2 p.

Extracellular signal-regulated activation of Rap1 fails to interfere in Ras effector signalling

Zwartkruis G.J.T., Wolthuis R.M.F., Nabben N.M.J.M., Franke B., Bos J.L. 1998, In: EMBO Journal. 17 , p. 5905-5912 8 p.

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