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dr. G.J.T. Zwartkruis

dr. G.J.T. Zwartkruis

Associate Professor

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Research Output (55)

Biochemistry of the Rap-Specific Guanine Nucleotide Exchange Factors PDZ-GEF1 and -2.

Kuiperij H.B., Rehmann H., Zwartkruis G.J.T. 2006, In: Methods in Enzymology. 407 , p. 174-186 13 p.

HRap1 B-retro: a novel human processed rap1B gene blurs the picture?

Zemojtel T, Penzkofer T., Duchniewicz M, Zwartkruis G.J.T. 2006, In: Leukemia. 20 , p. 145-146 2 p.

Rap1A-deficient T and B cells show impaired integrin-mediated cell adhesion.

Duchniewicz M, Zemojtel T, Kolanczyk M., Grossmann S., Scheele J.S., Zwartkruis G.J.T. 2006, In: Molecular and Cellular Biology. 26 , p. 643-653 11 p.

Requirement of the Caenorhabditis elegans RapGEF pxf-1 and rap-1 for epithelial integrity

Pellis-Van Berkel W., Verheijen M. H.G., Cuppen E., Asahina M., De Rooij J., Jansen G., Plasterk R. H.A., Bos J. L., Zwartkruis F. J.T. 1 Jan 2005, In: Molecular Biology of the Cell. 16 , p. 106-116 11 p.

Activation of FoxO transcription factors contributes to the antiproliferative effect of cAMP

Kuiperij H.B., van der Horst A.A., Raaijmakers J.H., Weijzen S., Medema R.H., Bos J.L., Burgering B.M.T., Zwartkruis G.J.T. 2005, In: Oncogene. 24 , p. 2087-2095 9 p.

Amino acids mediate mTOR/raptor signaling through activation of class 3 phosphatidylinositol 30H-kinase

Nobukuni T., Joaquin M., Roccio M., Dann S.G., Kim S.Y., Gulati P., Byfield M.P., Backer J.M., Natt F., Bos J.L., Zwartkruis G.J.T., Thomas G. 2005, In: Proceedings of the National Academy of Sciences of the United States of America. 102 , p. 14238-14243 6 p.

Regulation of the small GTPase Rheb by amino acids

Roccio M., Bos J.L., Zwartkruis G.J.T. 2005, In: Oncogene. 25 , p. 657-64 8 p.

Rap1 signaling is required for suppression of Ras-generated reactive oxygen species and protection against oxidative stress in T lymphocytes

Remans P.H., Gringhuis S.I., van Laar J.M., Sanders M.E., Papendrecht-van der Voort E.A., Zwartkruis G.J.T., Levarht E.W., Rosas Rosas M., Coffer P.J, Breedveld F.C., Bos J.L., Tak P.P., Verweij C.L., Reedquist K.A. 15 Jul 2004, In: Journal of Immunology. 173 , p. 920-931 12 p.

Detecting cAMP-induced Epac activation by fluorescence resonance energy transfer: Epac as a novel cAMP indicator

Ponsioen B., Zhao J., Riedl J.A., Zwartkruis G.J.T., van der Krogt G., Zaccolo M., Moolenaar W.H., Bos J.L., Jalink K.P. 2004, In: EMBO Reports. 12 , p. 1176-1180 5 p.

Rap1 regulates E-cadherin-mediated cell-cell adhesion.

Price L.S., Hajdo-Milasinovic A, Zhao J., Zwartkruis G.J.T., Collard J.G., Bos J.L. 2004, In: Journal of Biological Chemistry. 279 , p. 35127-35132 6 p.

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