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prof. dr. W.L. (Wouter) de Laat

prof. dr. W.L. (Wouter) de Laat

Full Professor

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Research Output (91)

Enhancers reside in a unique epigenetic environment during early zebrafish development

Kaaij Lucas J T, Mokry Michal, Zhou Meng, Musheev Michael, Geeven Geert, Melquiond Adrien S J, de Jesus Domingues António M., de Laat Wouter, Niehrs Christof, Smith Andrew D., Ketting René F. 5 Jul 2016, In: Genome Biology. 17

The second decade of 3C technologies:Detailed insights into nuclear organization

Denker Annette, De Laat Wouter 15 Jun 2016, In: Genes and Development. 30 , p. 1357-1382 26 p.

Discovery and validation of sub-threshold genome-wide association study loci using epigenomic signatures

Wang Xinchen, Tucker Nathan R., Rizki Gizem, Mills Robert, Krijger Peter Hugo Lodewijk, de Wit Elzo, Subramanian Vidya, Bartell Eric, Nguyen Xinh Xinh, Ye Jiangchuan, Leyton-Mange Jordan, Dolmatova Elena V., Harst Pim Van Der, Laat Wouter De, Ellinor Patrick T., Newton-Cheh Christopher, Milan David J., Kellis Manolis, Boyer Laurie A. 10 May 2016, In: eLife. 2016

Cell-of-origin-specific 3D genome structure acquired during somatic cell reprogramming

Krijger Peter Hugo Lodewijk, Di Stefano Bruno, de Wit Elzo, Limone Francesco, Van Oevelen Chris, De Laat Wouter, Graf Thomas 5 May 2016, In: Cell Stem Cell. 18 , p. 597-610 14 p.

Epigenomic annotation of gene regulatory alterations during evolution of the primate brain

Vermunt Marit W., Tan Sander C., Castelijns Bas, Geeven Geert, Reinink Peter, de Bruijn Ewart, Kondova Ivanela, Persengiev Stephan, Bontrop Ronald, Cuppen Edwin, de laat Wouter, Creyghton Menno P., Mar 2016, In: Nature Neuroscience. 19 , p. 494-503 13 p.

Erratum to: Dynamics of gene silencing during X inactivation using allele-specific RNA-seq [Genome Biol. 2015;16:149]

Marks Hendrik, Kerstens Hindrik H D, Barakat Tahsin Stefan, Splinter Erik, Dirks René A M, van Mierlo Guido, Joshi Onkar, Wang Shuang Yin, Babak Tomas, Albers Cornelis A., Kalkan Tüzer, Smith Austin, Jouneau Alice, de Laat Wouter, Gribnau Joost, Stunnenberg Hendrik G. 5 Feb 2016, In: Genome Biology. 17

Cause and Consequence of Tethering a SubTAD to Different Nuclear Compartments

Wijchers Patrick J., Krijger Peter H L, Geeven Geert, Zhu Yun, Denker Annette, Verstegen Marjon J A M, Valdes-Quezada Christian, Vermeulen Carlo, Janssen Mark, Teunissen Hans, Anink-Groenen Lisette C M, Verschure Pernette J., de Laat Wouter 4 Feb 2016, In: Molecular Cell. 61 , p. 461-473 13 p.

A p53-bound enhancer region controls a long intergenic noncoding RNA required for p53 stress response

Melo C A, Léveillé N, Rooijers K, Wijchers P J, Geeven G, Tal A, Melo S A, de Laat W, Agami R 18 Jan 2016, In: Oncogene. 35 , p. 4399–4406

CTCF Binding Polarity Determines Chromatin Looping

de Wit Elzo, Vos Erica S M, Holwerda Sjoerd J B, Valdes-Quezada Christian, Verstegen Marjon J A M, Teunissen Hans, Splinter Erik, Wijchers Patrick J, Krijger Peter H L, de Laat Wouter 19 Nov 2015, In: Molecular Cell. 60 , p. 676-84 9 p.

Transcription of Mammalian cis-Regulatory Elements Is Restrained by Actively Enforced Early Termination

Austenaa Liv M I, Barozzi Iros, Simonatto Marta, Masella Silvia, Della Chiara Giulia, Ghisletti Serena, Curina Alessia, de Wit Elzo, Bouwman Britta A M, de Pretis Stefano, Piccolo Viviana, Termanini Alberto, Prosperini Elena, Pelizzola Mattia, de Laat Wouter, Natoli Gioacchino 5 Nov 2015, In: Molecular Cell. 60 , p. 460-474 15 p.

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