dr. ir. M. (Martijn) Froeling

dr. ir. M. (Martijn) Froeling

Assistant Professor
dr. ir. M. (Martijn) Froeling
  • Precision Imaging Group

Research Programs



Martijn Froeling has done his master’s (July 2009) in Biomedical Engineering at the Eindhoven University of Technology and Performed his PdD studies on Diffusion Tensor Imaging of the human forearm at the Amsterdam University Medical Center and the Eindhoven University of Technology under the supervision of Prof. Dr. Ir. Klaas Nicolay, Prof. Dr. Ir. Gustav Strijkers and Prof. Dr. Ir. Aart Nederveen. Since his Ph.D. (Oktober 2012) he has continued his work on quantitative MRI in various organs such as the brain, peripheral nerves, muscle, kidney, and heart. Since July 2012 he works at the High Field group of the University Medical Center focussing on coil and hardware development for 7T systems and multi-nuclei imaging and clinical studies into neuromuscular diseases. Throughout his career, he has developed and maintained QMRITools for Mathematica, a toolbox for quantitative analysis of magnetic resonance imaging data of muscle, nerve, and heart. In 2021, he was awarded an NWO Vidi grant. In this project, he will study the relation between muscle architecture, microstructure, and function using multi-parametric quantitative MRI. This grant has been the basis for the muscle atlas project, a repository of quantitative MRI muscle data and methods.

Research Output (118)

Leisure time physical activity is associated with improved diastolic heart function and is partly mediated by unsupervised quantified metabolic health

Klarenberg Hugo, van der Velde Jeroen Hpm, Peeters Carel Fw, Dekkers Ilona A, de Mutsert R, Jukema J Wouter, Rosendaal Frits R, Leiner Tim, Froeling Martijn, Jorstad Harald, Boekholdt S Matthijs, Strijkers Gustav J, Lamb Hildo J 6 Feb 2024, In: BMJ open sport & exercise medicine. 10 12 p.

Monitoring Nusinersen Treatment Effects in Children with Spinal Muscular Atrophy with Quantitative Muscle MRI

Otto Louise A.M., Froeling M., Van Eijk Ruben P.A., Wadman Renske I., Cuppen Inge, Van Der Woude Danny R., Bartels Bart, Asselman Fay Lynn, Hendrikse Jeroen, Van Der Pol W. Ludo 2 Jan 2024, In: Journal of Neuromuscular Diseases. 11 , p. 91-101 11 p.

Muscle diffusion MRI reveals autophagic buildup in a mouse model for Pompe disease

Rohm Marlena, Russo Gabriele, Helluy Xavier, Froeling Martijn, Umathum Vincent, Südkamp Nicolina, Manahan-Vaughan Denise, Rehmann Robert, Forsting Johannes, Jacobsen Frank, Roos Andreas, Shin Yoon, Schänzer Anne, Vorgerd Matthias, Schlaffke Lara 20 Dec 2023, In: Scientific Reports. 13 , p. 1-12 12 p.

A three-dimensional Magnetic Resonance Spin Tomography in Time-domain protocol for high-resolution multiparametric quantitative magnetic resonance imaging

Liu Hongyan, van der Heide Oscar, Versteeg Edwin, Froeling Martijn, Fuderer Miha, Xu Fei, van den Berg Cornelis A T, Sbrizzi Alessandro 19 Oct 2023, In: NMR in Biomedicine. 37

In vivo phosphorus magnetic resonance spectroscopic imaging of the whole human liver at 7 T using a phosphorus whole-body transmit coil and 16-channel receive array:Repeatability and effects of principal component analysis-based denoising

van den Wildenberg Lieke, Gursan Ayhan, Seelen Leonard W.F., van der Velden Tijl A., Gosselink Mark W.J.M., Froeling Martijn, van der Kemp Wybe J.M., Klomp Dennis W.J., Prompers Jeanine J. May 2023, In: NMR in Biomedicine. 36

Diffusion tensor imaging and quantitative T2 mapping to monitor muscle recovery following hamstring injury

Monte Jithsa R., Hooijmans Melissa T., Froeling Martijn, Oudeman Jos, Tol Johannes L., Strijkers Gustav J., Nederveen Aart J., Maas Mario 2023, In: NMR in Biomedicine. 36

A 3-slice cardiac quantitative native and post-contrast T1 and T2 MRI protocol requiring only four BHs using a 72-channel receive array coil

Klarenberg Hugo, Gosselink Mark, Siddiqui Fasiha, Coolen Bram F, Nederveen Aart J, Leiner Tim, Lamb Hildo J, Boekholdt S Matthijs, Strijkers Gustav J, Froeling Martijn 2023, In: Frontiers in Cardiovascular Medicine. 10

Effect of two eccentric hamstring exercises on muscle architectural characteristics assessed with diffusion tensor MRI

Suskens Jozef J M, Secondulfo Laura, Kiliç Özgür, Hooijmans Melissa T, Reurink Gustaaf, Froeling Martijn, Nederveen Aart J, Strijkers Gustav J, Tol Johannes L 13 Dec 2022, In: Scandinavian Journal of Medicine & Science in Sports. 33 , p. 393-406 14 p.

Diffusion-weighted MRI with deep learning for visualizing treatment results of MR-guided HIFU ablation of uterine fibroids

Slotman Derk J, Bartels Lambertus W, Zijlstra Aylene, Verpalen Inez M, van Osch Jochen A C, Nijholt Ingrid M, Heijman Edwin, van 't Veer-Ten Kate Miranda, de Boer Erwin, van den Hoed Rolf D, Froeling Martijn, Boomsma Martijn F 6 Dec 2022, In: European Radiology. 33 , p. 4178-4188 11 p.

Quantitative muscle MRI captures early muscle degeneration in calpainopathy

Forsting Johannes, Rohm Marlena, Froeling Martijn, Güttsches Anne-Katrin, Südkamp Nicolina, Roos Andreas, Vorgerd Matthias, Schlaffke Lara, Rehmann Robert 16 Nov 2022, In: Scientific Reports. 12

All research output

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