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prof. dr. A.D.R. (Alwin) Huitema

prof. dr. A.D.R. (Alwin) Huitema

Full Professor

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Research Output (286)

A Population Pharmacokinetic Modelling Approach to Unravel the Complex Pharmacokinetics of Vincristine in Children

Nijstad A Laura, Chu Wan-Yu, de Vos-Kerkhof Evelien, Enters-Weijnen Catherine F, van de Velde Mirjam E, Kaspers Gertjan J L, Barnett Shelby, Veal Gareth J, Lalmohamed Arief, Zwaan C Michel, Huitema Alwin D R Oct 2022, In: Pharmaceutical Research. 39 , p. 2487-2495 9 p.

The influence of body mass index on the tolerability and effectiveness of full-weight-based paclitaxel chemotherapy in women with early-stage breast cancer

Lin Lishi, Soesan Marcel, van Balen Dorieke E M, Beijnen Jos H, Huitema Alwin D R Oct 2022, In: Breast Cancer Research and Treatment. 195 , p. 325-331 7 p.

Exposure–Response Analysis of Osimertinib in EGFR Mutation Positive Non-Small Cell Lung Cancer Patients in a Real-Life Setting

Boosman René J., Jebbink Merel, Veldhuis Wouter B., Groenland Stefanie L., van Veggel Bianca A.M.H., Moeskops Pim, de Langen Adrianus J., Beijnen Jos H., Smit Egbert F., Huitema Alwin D.R., Steeghs Neeltje Oct 2022, In: Pharmaceutical Research. 39 , p. 2507-2514 8 p.

Feasibility of therapeutic drug monitoring of sorafenib in patients with liver or thyroid cancer

Guchelaar Niels A D, van Eerden Ruben A G, Groenland Stefanie L, Doorn Leni van, Desar Ingrid M E, Eskens Ferry A L M, Steeghs Neeltje, van Erp Nielka P, Huitema Alwin D R, Mathijssen Ron H J, Koolen Stijn L W, Sep 2022, In: Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie. 153

An easy, fast, and efficient assay for the quantification of peptide Hepcidin-25 in serum and plasma with LC-MS/MS

Punt Arjen M, Wieman Joëlle C, van der Elst Kim Cm, Huitema Alwin Dr, Lentjes Eef Gwm Sep 2022, In: Annals of Clinical Biochemistry. 59 , p. 330-337 8 p.

Predictiveness of the Human-CYP3A4-Transgenic Mouse Model (Cyp3aXAV) for Human Drug Exposure of CYP3A4-Metabolized Drugs

Damoiseaux David, Li Wenlong, Martínez-Chávez Alejandra, Beijnen Jos H, Schinkel Alfred H, Huitema Alwin D R, Dorlo Thomas P C 13 Jul 2022, In: Pharmaceuticals. 15

A highly sensitive bioanalytical method for the quantification of vinblastine, vincristine, vinorelbine and 4-O-deacetylvinorelbine in human plasma using LC-MS/MS

van der Heijden L T, Gebretensae A, Thijssen B, van Andel L, Nijstad A L, Wang Y, Rosing H, Huitema A D R, Beijnen J H 5 Jun 2022, In: Journal of Pharmaceutical and Biomedical Analysis. 215 , p. 1-8

Deep learning body-composition analysis of clinically acquired CT-scans estimates creatinine excretion with high accuracy in patients and healthy individuals

Pieters Tobias T., Veldhuis W. B., Moeskops P., de Vos B. D., Verhaar M. C., Haitjema S., Huitema A. D.R., Rookmaaker M. B. 30 May 2022, In: Scientific Reports. 12

Efficacy and toxicity of vemurafenib and cobimetinib in relation to plasma concentrations, after administration via feeding tube in patients with BRAF-mutated thyroid cancer:a case series and review of literature

van Berge Henegouwen J M, van der Wijngaart H, Zeverijn L J, Hoes L R, Meertens M, Huitema A D R, Devriese L A, Labots M, Verheul H M W, Voest E E, Gelderblom H 22 May 2022, In: Cancer Chemotherapy and Pharmacology. 90 , p. 97-104 8 p.

Is age just a number?:A population pharmacokinetic study of gemcitabine

Boosman René J, Crombag Marie-Rose B S, van Erp Nielka P, Beijnen Jos H, Steeghs Neeltje, Huitema Alwin D R May 2022, In: Cancer Chemotherapy and Pharmacology. 89 , p. 697-705 9 p.

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