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prof. dr. A.D.R. (Alwin) Huitema

prof. dr. A.D.R. (Alwin) Huitema

Full Professor

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Research Output (286)

Renal function-based versus standard dosing of pemetrexed:a randomized controlled trial

de Rouw Nikki, Boosman René J., Burgers Jacobus A., Huitema Alwin D.R., Dingemans Anne Marie C., Derijks Hieronymus J., Burger David M., Piet Berber, Hendriks Lizza E.L., Biesma Bonne, Pruis Melinda A., Dumoulin Daphne W., Croes Sander, Mathijssen Ron H.J., van den Heuvel Michel M., ter Heine Rob Jan 2023, In: Cancer Chemotherapy and Pharmacology. 91 , p. 33-42 10 p.

Therapeutic drug monitoring guided dosing versus standard dosing of alectinib in advanced ALK positive non-small cell lung cancer patients:Study protocol for an international, multicenter phase IV randomized controlled trial (ADAPT ALEC)

Meertens Marinda, Muntinghe-Wagenaar M. Benthe, Sikkema Barend J., Lopez-Yurda Marta, Retèl Valesca P., Paats Marthe S., Ter Heine Rob, Schuuring Ed, Timens Wim, Touw Daan J., van Boven Job F.M., de Langen Adrianus J., Hashemi Sayed M.S., Hendriks Lizza E.L., Croes Sander, van den Heuvel Michel M., Dingemans Anne Marie C., Mathijssen Ron H.J., Smit Egbert F., Huitema Alwin D.R., Steeghs Neeltje, van der Wekken Anthonie J. 2023, In: Frontiers in oncology. 13 9 p.

Klinische farmacologie van cytotoxische geneesmiddelen bij pasgeborenen en zuigelingen

Nijstad Laura, Lalmohamed Arief, Zwaan C.M., Huitema AD 2023, In: Nederlands Tijdschrift voor Oncologie. 20 , p. 17-24

Optimizing carboplatin dosing by an improved prediction of carboplatin clearance using a CT-enhanced estimate of renal function

Molenaar-Kuijsten L, Pieters T T, Veldhuis W B, Moeskops P, Rijkhorst E J, Dorlo T P C, Beijnen J H, Steeghs N, Rookmaaker M B, Huitema A D R 2023, In: British Journal of Clinical Pharmacology. 89 , p. 3016-3025 10 p.

Practical Recommendations for the Manipulation of Kinase Inhibitor Formulations to Age-Appropriate Dosage Forms

Bernsen Emma C, Hogenes Valery J, Nuijen Bastiaan, Hanff Lidwien M, Huitema Alwin D R, Diekstra Meta H M 17 Dec 2022, In: Pharmaceutics. 14

Genetic variants found in paediatric oncology patients with severe chemotherapy-induced toxicity:A case series

Bernsen E C, Hanff L M, Haveman L M, Tops Bbj, van der Lee M, Swen J J, Huitema Adr, Diekstra Mhm 4 Dec 2022, In: Journal of Oncology Pharmacy Practice. 29 , p. 1237-1245 9 p.

Overestimation of the effect of (fos)aprepitant on intravenous dexamethasone pharmacokinetics requires adaptation of the guidelines for children with chemotherapy-induced nausea and vomiting

Nijstad A Laura, de Vos-Kerkhof Evelien, Enters-Weijnen Catherine F, van de Wetering Marianne D, Tissing Wim J E, Tibben Matthijs M, Rosing Hilde, Lalmohamed Arief, Huitema Alwin D R, Zwaan C Michel Dec 2022, In: Supportive Care in Cancer. 30 , p. 9991-9999 9 p.

Pharmacokinetics and Pharmacodynamics of PARP Inhibitors in Oncology

Bruin Maaike A C, Sonke Gabe S, Beijnen Jos H, Huitema Alwin D R Dec 2022, In: Clinical Pharmacokinetics. 61 , p. 1649-1675 27 p.

Idiopathic hyperammonemic encephalopathy secondary to gemcitabine-cisplatin treatment

Verkerk Karlijn, Otten Hans-Martin, Huitema Alwin D R Nov 2022, In: Cancer Chemotherapy and Pharmacology. 90 , p. 417-419 3 p.

Semi-mechanistic Modeling of Hypoxanthine, Xanthine, and Uric Acid Metabolism in Asphyxiated Neonates

Chu Wan-Yu, Allegaert Karel, Dorlo Thomas P C, Huitema Alwin D R, Nov 2022, In: Clinical Pharmacokinetics. 61 , p. 1545-1558 14 p.

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