dr. T.P.C. van Doormaal

dr. T.P.C. van Doormaal

Associate Professor - medical
dr. T.P.C. van Doormaal
  • Neurochirurgen

Research Programs



My research focusses on the bench to bedside development of devices that improve outcome of patients with a neurosurgical disease. 

I started my research carreer as a PhD in the group of Prof CAF Tulleken and Prof A van der Zwan at the UMC Utrecht, and I co-invented several ways to make a bypass in the brain. These techniques were ultimately used to treat patients.

After my PhD, during my neurosurgical trianing, I invented and co-developed a new sealant (in the media it is referred to as 'plaster') to prevent cerebrospinal fluid leakage after brain surgery.  I did all developents under public private flag together with Polyganics BV, and the intellectual property (IP) was transferred from UMC Utrecht to this company to make the technique available for patients. The device (formally called 'Liqoseal') is now standard of care in Europe and under research in the USA.

A few years ago I started to do research with Augmented Reality to inform patients, train residents and provide active guidance during brain surgery. The IP I developed was tranferred to a UMC Utrecht spinoff called 'Augmedit'. I combine my function as a neurosurgeon, nowadays both in the UMC Utrecht and the University Medical Center in Zurich, Switserland, with being Chief Medical Officer of this company. My research group in the UMCU works closely together with Augmedit, the Prinsess Maxima Center and University Medical Center Zurich to design optimal software to inform patients, train residents and to ultimately prevent complications during brainsurgery. 

Side Activities

Consultant Polyganics BV, Groningen, The Netherlands

Chief Medical Officer Augmedit bv, Amsterdam, The Netherlands

Neurosurgeon University Medical Center Zurich, Switserland

Research Output (62)

Clinical potential of automated convolutional neural network-based hematoma volumetry after aneurysmal subarachnoid hemorrhage

Thomson Bart R., Gürlek Firat, Buzzi Raphael M., Schwendinger Nina, Keller Emanuela, Regli Luca, van Doormaal Tristan PC, Schaer Dominik J., Hugelshofer Michael, Akeret Kevin Nov 2023, In: Journal of Stroke and Cerebrovascular Diseases. 32

Application of virtual and mixed reality for 3D visualization in intracranial aneurysm surgery planning:a systematic review

Colombo Elisa, Lutters Bart, Kos Tessa, van Doormaal Tristan 27 Sep 2023, In: Frontiers in surgery. 10 8 p.

Effect of Intraoperative Mixed-Reality use on Nonsurgical Team Members in the Neurosurgical Operating Room: An Explorative Study

Kos Tessa, Haaksman Sabrina, Regli Luca , van Doormaal TPC, Colombo Elisa 23 Sep 2023, In: World Neurosurgery. 180 , p. e219-e225 7 p.

Comparing the influence of mixed reality, a 3D viewer, and MRI on the spatial understanding of brain tumours

Fick T., Meulstee J. W., Köllen M. H., Van Doormaal J. A.M., Van Doormaal T. P.C., Hoving E. W. 4 Aug 2023, In: Frontiers in Virtual Reality. 4 , p. 1-9

Risk Factors and Management of Incisional Cerebrospinal Fluid Leakage after Craniotomy:A Retrospective International Multicenter Study

Kinaci Ahmet, Slot Emma M.H., Kollen Mare, Germans Menno R., Amin-Hanjani Sepideh, Carlson Andrew P., Majeed Kashif, Depauw Paul R.A.M., Robe Pierre A., Regli Luca, Charbel Fady T., van Doormaal Tristan P.C. 1 Jun 2023, In: Neurosurgery. 92 , p. 1177-1182 6 p.

Incisional CSF leakage after intradural cranial surgery in children:incidence, risk factors, and complications

Slot Emma M.H., van Doormaal Tristan P.C., van Baarsen Kirsten M., Krayenbühl Niklaus, Regli Luca, Germans Menno R., Hoving Eelco W. Apr 2023, In: Journal of Neurosurgery: Pediatrics. 31 , p. 313-320 8 p.

Cerebrospinal fluid leakage after intradural spinal surgery in children

Slot Emma M.H., van Doormaal Tristan P.C., van Baarsen Kirsten M., Krayenbühl Niklaus, Regli Luca, Germans Menno R., Hoving Eelco W. Apr 2023, In: Child's Nervous System. 39 , p. 1013-1019 7 p.

Mixed Reality in Modern Surgical and Interventional Practice: Narrative Review of the Literature

Vervoorn Mats, Wulfse Maaike, van Doormaal T.P.C., Ruurda Jelle, van der Kaaij NP, de Heer Linda 2023, In: JMIR Serious Games. 11

Development of the SAFETEA Scores for Predicting Risks of Complications of Preventive Endovascular or Microneurosurgical Intracranial Aneurysm Occlusion

Algra Annemijn M., Greving Jacoba P., De Winkel Jordi, Kurtelius Arttu, Laban Kamil, Verbaan Dagmar, Van Den Berg René, Vandertop William, Lindgren Antti, Krings Timo, Woo Peter Y.M., Wong George K.C., Roozenbeek Bob, Van Es Adriaan C.G.M., Dammers Ruben, Etminan Nima, Boogaarts Hieronymus, Van Doormaal Tristan, Van Der Zwan Albert, Van Der Schaaf Irene C., Rinkel Gabriël J.E., Vergouwen Mervyn D.I. 2 Sep 2022, In: Neurology. 99 , p. E1725-E1737

All research output

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