W.L. de Laat

Persoonlijke prijzen, subsidies en onderscheidingen

• VIDI career grant (2000)
• ERC Starting Grant (2008)
• EMBO onderzoeker(2008)

Afdelingen / poliklinieken

Key Publications:

• Simonis M, Kooren J, de Laat W. (2007). An evaluation of 3C-based methods to capture DNA interactions. Nature Methods 4:895-901.
• Simonis, M., Klous, P., Splinter, E., Moshkin, Y., Willemsen, R., de Wit, E.,van Steensel, B., de Laat, W. (2006). Nuclear organization of active and inactive chromatin domains uncovered by chromosome conformationcapture-on-chip (4C). Nature Genetics 38:1348-1354.
• Splinter, E., Heath, H., Kooren, J., Palstra, R.J., Klous, P., Grosveld, F., Galjart, N., de Laat, W. (2006). CTCF mediates long-range chromatin looping and local histone modification in the beta-globin locus. Genes &Development 20: 2349-2354.
• Palstra R-J., Tolhuis B., Splinter E., Nijmeijer R., Grosveld F., de Laat W.(2003). The b-globin nuclear compartment in development and erythroid differentiation. Nature Genetics 35, 190-194.
• Tolhuis B., Palstra R-J, Splinter E., Grosveld F., de Laat W. (2002). Looping and interaction between hypersensitive sites in the active b-globinlocus. Molecular Cell 10: 1453-1465